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Domcet Tablet
Domperidone (10mg)+ Paracetamol (325mg)
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Domcet Tablet is a prescription medicine used in the treatment of migraine. It prevents pain signals to reach the brain to reduce pain. It also blocks certain substances in the brain that trigger nausea or vomiting during migraine headaches.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)
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General Information
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Product introduction
Domcet Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effect is dryness in mouth. This is temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about these side effects. Migraine attacks can be managed by identifying migraine-causing triggers which may be red wine, caffeine withdrawal, stress, and skipped meals, etc. You can identify personal triggers by maintaining a diary of what you are doing, what you are eating, and any stressful activity happened before migraine attack.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
The most common side effect is dryness in mouth. This is temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about these side effects. Migraine attacks can be managed by identifying migraine-causing triggers which may be red wine, caffeine withdrawal, stress, and skipped meals, etc. You can identify personal triggers by maintaining a diary of what you are doing, what you are eating, and any stressful activity happened before migraine attack.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Uses of Domcet Tablet
Benefits of Domcet Tablet
Treatment of Migraine
Domcet Tablet is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
Domcet Tablet is a combination of medicines that helps prevent migraine by changing the way that your nerves receive pain signals. It also blocks the action of chemicals in the body that can make you feel or be sick. This treats as well as prevents nausea or vomiting effectively. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.
Side effects of Domcet Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Domcet
- Dryness in mouth
How to use Domcet Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Domcet Tablet is to be taken on an empty stomach.
How Domcet Tablet works
Domcet Tablet is a combination of two medicines: Domperidone and Paracetamol. Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.
All substitutes for Domcet Tablet
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Domcet Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Inform your doctor if you are taking any pain relief medicine.
- Domcet Tablet can only decrease the number and severity of attacks but may not completely stop them.
- Some tips that may help avoid a migraine attack:
- Have your meals at the same time every day.
- Avoid bright lights and extreme temperatures.
- Avoid loud music and noisy places.
- Avoid chocolates, cheese, processed food, alcohol, and smoking.
- Get sufficient sleep and avoid stress.
- Domcet Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Inform your doctor if you are taking any pain relief medicine.
- Domcet Tablet can only decrease the number and severity of attacks but may not completely stop them.
- Some tips that may help avoid a migraine attack:
- Have your meals at the same time every day.
- Avoid bright lights and extreme temperatures.
- Avoid loud music and noisy places.
- Avoid chocolates, cheese, processed food, alcohol, and smoking.
- Get sufficient sleep and avoid stress.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Domcet Tablet

Pregnancy
CONSULT YOUR DOCTOR
The safety of Domcet Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CAUTION
Domcet Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
UNSAFE
Domcet Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Domcet Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
UNSAFE
Domcet Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Domcet Tablet is not recommended in patients with severe liver disease and active liver disease.
However, the use of Domcet Tablet is not recommended in patients with severe liver disease and active liver disease.
Frequently asked questions
Domcet Tablet is a combination of two medicines: Domperidone and Paracetamol/Acetaminophen. Domperidone helps to control vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol/Acetaminophen is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.
No, taking a higher than the recommended dose of Domcet Tablet can increase the risks of side effects and liver damage. If you are experiencing increased severity of symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
No, there is no report of any patient getting addicted to Domcet Tablet.
Yes, Domcet Tablet can cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
References

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User feedback
Once A Day
59%
Twice A Day
25%
Thrice A Day
14%
Alternate Day
1%
Four Times A Day
1%
Migraine
45%
Others
34%
Headache
21%
Average
40%
Excellent
32%
Poor
28%
No Side Effect
33%
Allergic reaction
33%
Dryness in mouth
33%
With food
60%
With or without food
33%
Empty stomach
7%
Average
57%
Not Expensive
24%
Expensive
19%
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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Domcet Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Domcet Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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