


Dolorin Tablet
Caffeine (50mg)+ Domperidone (10mg)+ Paracetamol (650mg)
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Dolorin Tablet is a prescription medicine used in the treatment of migraine. It blocks certain substances in the brain that trigger nausea or vomiting during migraine headaches.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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General Information
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Product introduction
Dolorin Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are dryness in mouth, increased heart rate, and restlessness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. Migraine attacks can be managed by identifying migraine-causing triggers which may be red wine, caffeine withdrawal, stress, and skipped meals, etc. You can identify personal triggers by maintaining a diary of what you are doing, what you are eating, and any stressful activity happened before migraine attack.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. While taking this medicine to try to avoid caffeine-containing food like chocolate, coffee, energy drinks, green tea, black tea, dark chocolate, etc.
The most common side effects are dryness in mouth, increased heart rate, and restlessness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. Migraine attacks can be managed by identifying migraine-causing triggers which may be red wine, caffeine withdrawal, stress, and skipped meals, etc. You can identify personal triggers by maintaining a diary of what you are doing, what you are eating, and any stressful activity happened before migraine attack.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. While taking this medicine to try to avoid caffeine-containing food like chocolate, coffee, energy drinks, green tea, black tea, dark chocolate, etc.
Uses of Dolorin Tablet
Benefits of Dolorin Tablet
Migraine
Dolorin Tablet is a combination of medicines that treat and prevent migraine headaches. It changes the electrical activity in the brain, blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. It also contains caffeine that stimulates your brain to uplift your mood and give you a feeling of well being by improving your energy levels. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.
Dolorin Tablet is a combination of medicines that treat and prevent migraine headaches. It changes the electrical activity in the brain, blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. It also contains caffeine that stimulates your brain to uplift your mood and give you a feeling of well being by improving your energy levels. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.
Side effects of Dolorin Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dolorin
- Dryness in mouth
- Increased heart rate
- Restlessness
How to use Dolorin Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dolorin Tablet may be taken with or without food.
Avoid Dolorin Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.
Avoid Dolorin Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.
How Dolorin Tablet works
Dolorin Tablet is a combination of three medicines: caffeine, domperidone and paracetamol. Caffeine narrows the blood vessels in the brain to reduce headache. It also increases the effectiveness of paracetamol. Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. Paracetamol is an analgesic (pain reliever) and anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that causes fever and pain.
Quick tips
- Dolorin Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
- A number of things can trigger migraines in some people. These can include some foods (for example, cheese, chocolate, and red wine), worry, bright sunlight, too much or too little sleep, and skipping meals. Keep a track of what triggers your migraine and try to avoid that.
- Inform your doctor if you are taking any other pain relief medicine.
- Try to keep your follow-up appointments with your doctor. Dolorin Tablet will only be prescribed for short-term use -- it must not be taken for more than five consecutive days.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Dolorin Tablet

Pregnancy
CONSULT YOUR DOCTOR
The safety of Dolorin Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CAUTION
Dolorin Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
UNSAFE
Dolorin Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Dolorin Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Dolorin Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Dolorin Tablet is not recommended in patients with severe liver disease and active liver disease.
However, the use of Dolorin Tablet is not recommended in patients with severe liver disease and active liver disease.
Fact Box
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Embiotic Laboratories Pvt Ltd
Address: 20C, Ist Phase, Kumbalgodu Industrial Area, Mysore Road, Kumbalgodu, 1st Phase, Bengaluru, Karnataka 560074.
Address: 20C, Ist Phase, Kumbalgodu Industrial Area, Mysore Road, Kumbalgodu, 1st Phase, Bengaluru, Karnataka 560074.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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