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food interaction for DOLOMED MR

alcohol interaction for DOLOMED MR

pregnancy interaction for DOLOMED MR

lactation interaction for DOLOMED MR

There is no data available. Please consult doctor before consuming the drug.
Dolomed mr tablet may cause excessive drowsiness and calmness with alcohol.
Taking Ibuprofen with alcohol increases the risk of stomach bleeding.
Dolomed mr tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Ibuprofen(400 mg)


Ibuprofen is used for the relief of mild to moderate pain including pain in the joints and muscles, backache, pain in the nerve (neuralgia), headache, migraine (one-sided headache), dental pain, body pain, pain during the menstrual cycle, pain during menstruation (dysmenorrhea), as well as to treat fever and symptoms of cold and influenza. 

How it works

Ibuprofen belongs to the group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It relieves pain by blocking production of a certain natural substance (prostaglandin) that is released in the body during pain.

Common side effects

Nervousness, Flatulence, Abdominal bloating, Constipation, Diarrhoea, Dizziness, Ringing in ear
Paracetamol(325 mg)


Paracetamol is used for the relief of mild to moderate pain in conditions such as headache (including migraine), toothache, ear pain, joint pain, pain during menstruation, fever, feverish colds, and flu.

How it works

Paracetamol belongs to class of medications called analgesics (painkiller) and antipyretics (fever reducing). Paracetamol reduces pain by increasing the pain threshold. It reduces fever by acting on the temperature-regulating region of brain, resulting in increased blood flow across the skin, sweating and heat loss.

Common side effects

Skin redness, Allergic reaction, Shortness of breath, Running nose, Nausea, Liver injury, Abnormal blood cell count, Facial swelling, Blisters on skin
Chlorzoxazone(250 mg)


Chlorzoxazone is used to relieve pain and stiffness caused by muscle strains and sprains. 

How it works

Chlorzoxazone is a centrally acting muscle relaxant that causes muscle relaxation and reduces muscle stiffness by blocking nerve impulses (or pain sensations) that are sent to the brain of the central nervous system.

Common side effects

Nervousness, Ovarian hyperstimulation syndrome, Body ache, Dark colored urine, Dizziness, Drowsiness, Liver toxicity, Lightheadedness, Nausea


2 Substitutes
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Expert advice for DOLOMED MR

Take the drug with a meal or snack to prevent upset stomach.
  • Do not take the drug with other blood thinners like aspirin unless your doctor suggests.
  • Ibuprofen can cause easy bruising or bleeding, consult your doctor if you show any such signs.
Consult your doctor if you develop blurred vision, ringing  or roaring in ears. Avoid taking alcohol, salicylates to prevent bleeding. Do not start or continue the ibuprofen tablets: If you are allergic (hypersensitive) to ibuprofen or any of the other ingredients of ibuprofen.
Doctor’s advice should be considered before taking ibuprofen tablets in case of any following disease conditions such as:
  • Severe liver or kidney problems.                     
  • Heart failure or other heart problems.                    
  • High cholesterol.                     
  • Stomach ulcer,
  • perforation or bleeding due to NSAIDs.                     
Systemic Lupus Erythematosus (a condition of the immune system affecting connective tissue resulting in joint pain, skin change and disorders of other organs).

Frequently asked questions for DOLOMED MR


Q. Is Brufen and ibuprofen the same?
Yes, ibuprofen is available under brand name ‘Brufen’.
Q. Is ibuprofen/ Brufen/ Ibugesic / Ibugesic plus safe?
Ibuprofen (also available as Brufen/Ibugesic /Ibugesic plus) is safe at the prescribed dose by the doctor. Patients should follow the advice of the doctor regarding its use.
Q. Is ibuprofen/Brufen banned in India?
No. It is available in India.
Q. Is ibuprofen/ Brufen / Ibugesic/ Ibugesic plus an antibiotic?
No. Ibuprofen is a nonsteroidal anti-inflammatory drug and not an antibiotic.
Q. Can I take ibuprofen for a hangover/ heartburn/ heart attack?
Ibuprofen is specifically used to relieve pain. Always consult your doctor regarding its use.
Q. Can I take ibuprofen with amoxicillin/ DayQuil/ tramadol/ NyQuil/ prednisone/ hydrocodone/ sudafed/ antibiotics/ codeine/ paracetamol/ panadol?
Taking other medicines may alter the effects of ibuprofen. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does ibuprofen/ Brufen make you sleepy?
No. Patients should follow the advice of the doctor regarding its use.
Q. Does ibuprofen/ Brufen stop your period?
At normal prescribed doses, it doesn’t stop period. It is used to relieve from pain during period (menstruation). However, at high doses – about 800 mg dose three times a day, it can stop your period. However, it depends on a lot of factors. Patients should follow the advice of the doctor regarding its use.
Q. Does ibuprofen/Brufen reduce swelling /get you high /thin the blood?
No. However, consult your doctor if you experience any of these side effects.
Q. Does ibuprofen contain paracetamol/aspirin/ caffeine/ codeine?
No. Ibuprofen does not contain paracetamol/aspirin/caffeine/codeine.
Q. Is Brufen/ Ibugesic a painkiller/ anti-inflammatory/ good for toothache/ used for fever/ used for cramps/ used for flu/ used for cold/ used for stomach ache/ used for headache/ used for gall bladder pain/use for muscle soreness/use for sore throat/used for back pain/used for concussion/ used for inflammation?
Brufen or Ibugesic are trade names of ibuprofen, which is a nonsteroidal anti-inflammatory drug and used as painkiller for toothache, headache, back pain, gall bladder pain and cramps. It has inflammatory property, so used for inflammation, concussion, muscle soreness, sore throat. It is used for fever and flu. It is used with antihistamines for cold. Its better avoided for stomach pain.
Q. Does Brufen cause constipation?
It may cause constipation
Q. Does Brufen stop bleeding?
It is used to stop abnormal vaginal bleeding. However, consult your doctor if you experience such type of effects.


Q. Is paracetamol safe/ banned/ available in India?
Paracetamol (also known as acetaminophen, crocin, dolo, calpol, pacimol) is an over-the-counter drug available in India. It is generally safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is paracetamol a painkiller/ used for cold?
Paracetamol is used to relieve mild to moderate pain associated with cold and flu, as well as fever.
Q. Does paracetamol make you drowsy / sleepy? 
Paracetamol does not cause drowsiness. However, paracetamol is available in combination with cough and cold medicines (eg. cetirizine, chlorpheniramine), which may cause drowsiness or sleepiness.
Q. Is paracetamol an NSAID/ antibiotic?
Paracetamol is a anti-pyretic (anti-fever), anti -inflammatory drug, which belongs to the category of non-steroidal anti-inflammatory drug (NSAID). However, unlike other NSAIDS, paracetamol can relieve only mild to moderate pain.
It is not an antibiotic.
Q. Can I take crocin with cetirizine/ aceclofenac/ amoxicillin/ codeine/ tramadol/ warfarin/ erythromycin/ antibiotics?
Yes, paracetamol (available as crocin) can be taken with all of these drugs. Caution is advised when crocin is to be used with warfarin. However, always consult your doctor regarding combined use of crocin with any other drug.
Q. Can I take crocin with ibuprofen/naproxen/other NSAID?
Paracetamol (available as crocin) is available over-the-counter in combination with ibuprofen/naproxen/other NSAID. However, always consult your doctor regarding combined use of crocin with any other drug.
Q. Does paracetamol cause death?
Paracetamol on overdose can severely damage the liver and cause death. No more than 4 grams should be consumed in one day. Always consult your doctor regarding use of paracetamol.
Q. Can calpol make babies/ toddlers sleep/ help in teething pain?
Calpol can relieve pain in infants and children; it does not make them sleep.


Q. Is chlorzoxazone an opiate/ narcotic/ steroid/ controlled substance/ addictive?
No. Chlorzoxazone is mephenesin like centrally acting muscle relaxant that is used to relieve muscle stiffness and pain. It is not a steroid, narcotic, addictive or controlled substance.
Q. Does chlorzoxazone be used for recreational purposes?
No, chlorzoxazone or any other drug should not be used for recreational purpose. Use only when prescribed by the doctor.
Q. Does chlorzoxazone have aspirin or codeine in it?
No. It does not contain aspirin or codeine.
Q. Does chlorzoxazone induce drowsiness/ weight gain?
It is not known to cause weight gain, but may cause drowsiness. If you experience any such side effects, consult your doctor.
Q. Is chlorzoxazone like Vicodin?
No. Vicodin, which contains acetaminophen and hydrocodone, is used to relieve general pain. Chlorzoxazone is a muscle relaxant and different drug altogether.
Q. Is chlorzoxazone the same as Soma?
No. Soma caontains carisoprodol, another mephenesin-like centrally acting muscle relaxant. However, it totally different from chlorzoxazone.
Q. Can I take chlorzoxazone with tramadol, naproxen or ibuprofen?
No known interaction data is available for these drugs. However, it doesn’t mean that the chlorzoxazone can be taken with tramadol, naproxen or ibuprofen. Always consult your doctor regarding the drug usage.
Q. Can I take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen?
No. It is advisable not to take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen since interactions have been reported for this combination.


Content on this page was last updated on 25 March, 2016, by Dr. Varun Gupta (MD Pharmacology)