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Diprobate G Plus Cream

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 07 Jan 2026 | 03:32 PM (IST)
Diprobate G Plus Cream is used in the treatment of various types of skin infections. It prevents the growth of microorganisms that cause the infection. It also relieves the pain, irritation, and itchiness of the skin.
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Diprobate G Plus Cream image
Diprobate G Plus Cream image

Product introduction

Diprobate G Plus Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure the better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.

The most common side effects of this medicine are itching dryness, redness, and burning sensation at the application site. These are usually self-limiting. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.). Drink plenty of water and apply moisturizing cream or lotion to avoid of cope up with the side effects.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. If you are pregnant or breastfeeding, consult your doctor before using the medicine. If you are a known allergic to the medicine, you must refrain from using this medicine and discuss it with your doctor. Consult the doctor before receiving any cosmetic treatment.

Uses of Diprobate G Plus Cream

Benefits of Diprobate G Plus Cream

Treatment of Skin infections
Diprobate G Plus Cream helps treat and control skin infections caused by bacteria such as boils, impetigo (red sores on face), infection in the hair follicle, etc. It may also be used to prevent infections in small cuts, wounds, burns, or ulcers on your skin. Apply 2-3 times a day to get relief from itching, swelling, and redness caused by infection. You might see a change in your skin appearance in a week if used as prescribed by your doctor.

Side effects of Diprobate G Plus Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Diprobate G Plus
  • Application site reactions (burning, irritation, itching and redness)

How to use Diprobate G Plus Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Diprobate G Plus Cream works

Diprobate G Plus Cream is a combination of three medicines: Betamethasone and Gentamicin which treat skin infections. Betamethasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Gentamicin is an antibiotic which kills bacteria on the skin by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Zinc Sulfate is an antiseptic.

Quick tips

  • It may take several weeks to show its action. Keep using it as suggested by your doctor.
  • Wash your skin with a mild cleanser and pat it dry before applying Diprobate G Plus Cream.
  • Apply it as a thin layer onto a clean, dry, unbroken infected area of skin.
  • It may cause minor burning, stinging or irritation when applied. Inform your doctor if this does not go away.
  • Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas.
  • Use moisturizer regularly to overcome the skin dryness during the course of treatment.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Diprobate G Plus Cream is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Diprobate G Plus Cream may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Diprobate G Plus Cream is used in the treatment of various types of skin infections. It prevents the growth of microorganisms that cause the infection. It also relieves the pain, irritation, itchiness, etc. of the skin.
No, Diprobate G Plus Cream should not be used on open wounds, deep cuts, or broken skin, unless your doctor specifically advises it.
People should avoid using Diprobate G Plus Cream if they are allergic to betamethasone, gentamicin, zinc sulfate, or any ingredients. Also, inform your doctor if you have fungal, viral skin infections, or certain inflammatory conditions, like rosacea.
Prolonged use of Diprobate G Plus Cream may cause skin thinning, discoloration, or stretch marks, so use only as prescribed, and avoid applying to thin skin areas.
Use Diprobate G Plus Cream only for the time prescribed. Prolonged or excessive use increases the risk of side effects.
Yes, Diprobate G Plus Cream can worsen acne, perioral dermatitis, and rosacea. Inform your doctor if you have these conditions prior to use.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mepromax Life Sciences Pvt Ltd
Address: GIDC RESIDENTIAL PLOT NO. H/78 WADHWAN Surendranagar GJ 363035 IN

Vendor Details

Country of origin: India
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