






Diplene AF Cream
Clobetasol (0.05% w/w)+ Chlorocresol (0.1% w/w)
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Diplene AF Cream is a combination medicine that is used to treat various types of skin infections. It minimizes symptoms of inflammation such as redness, irritation, swelling, and itching of the skin.
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 27 Sep 2026 | 01:03 AM (IST)
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 27 Sep 2026 | 01:03 AM (IST)
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General Information
Contains
Clobetasol (0.05% w/w)+ Chlorocresol (0.1% w/w)
Marketer
Fulford India Ltd
Storage
Store below 25°C
The content is shown in English







Product introduction
Diplene AF Cream is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.
The most common side effect of this medicine includes itching, dryness, redness, and burning sensation at the application site. These are usually self-limiting. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.).
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution.
The most common side effect of this medicine includes itching, dryness, redness, and burning sensation at the application site. These are usually self-limiting. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.).
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution.
Uses of Diplene AF Cream
Benefits of Diplene AF Cream
Treatment of Skin infections
Diplene AF Cream gives relief from various discomfort associated with skin infections such as redness, swelling, pain, itching, and irritation. Its antiseptic property helps prevent infections in small cuts, wounds, burns, or ulcers on your skin. You may notice your skin starting to get better within 4-5 days. Keep using Diplene AF Cream for as long as it is prescribed.
Diplene AF Cream gives relief from various discomfort associated with skin infections such as redness, swelling, pain, itching, and irritation. Its antiseptic property helps prevent infections in small cuts, wounds, burns, or ulcers on your skin. You may notice your skin starting to get better within 4-5 days. Keep using Diplene AF Cream for as long as it is prescribed.
Side effects of Diplene AF Cream
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Diplene AF
- Burning sensation
- Stinging sensation
- Itching
How to use Diplene AF Cream
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Diplene AF Cream works
Diplene AF Cream is a combination of two medicines: Clobetasol and Chlorocresol. Clobetasol is a steroid medicine. It blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Chlorocresol is a preservative.
Quick tips
- It may take several weeks to show its action. Keep using it as suggested by your doctor.
- Wash your skin with a mild cleanser and pat it dry before applying Diplene AF Cream.
- Apply it as a thin layer onto clean, dry, unbroken skin affected by an infection.
- It may cause minor burning, stinging or irritation when applied. Inform your doctor if this does not go away.
- Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
The safety of Diplene AF Cream during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Diplene AF Cream during breastfeeding is not available. Please consult your doctor.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established
Fact Box
Habit Forming
No
Therapeutic Class
DERMA
References
- Clobetasol. Uxbridge, Middlesex: GlaxoSmithKline UK; 1993 [revised 18 Oct. 2017]. [Accessed 04 Apr. 2019] (online) Available from:
- ScienceDirect. Chlorocresol. [Accessed 03 Apr. 2019] (online) Available from:
- Clobetasol. Melville, New York: Fougera Pharmaceuticals Inc.; 1994. [revised Nov. 2012] [Accessed 04 Apr. 2019] (online) Available from:
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User feedback
Once A Day
78%
Twice A Day
20%
Twice A Week
2%
Skin infections
74%
Skin disorders
16%
Others
11%
Excellent
52%
Average
37%
Poor
11%
No Side Effect
100%
With or without food
57%
With food
29%
Empty stomach
14%
Average
52%
Expensive
33%
Not Expensive
14%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Fulford India Ltd
Address: Plot No. -810, Sector - 3 , Industrial Area , Pthampur Dist. Dhar - 454 775 (M.P.) India
Address: Plot No. -810, Sector - 3 , Industrial Area , Pthampur Dist. Dhar - 454 775 (M.P.) India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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