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DICLORIL MR 250MG/50MG/325MG TABLET

Navil Laboratories Pvt Ltd
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Composition FOR DICLORIL MR

Chlorzoxazone(250mg),Diclofenac(50mg),Paracetamol(325mg)

food interaction for DICLORIL MR

alcohol interaction for DICLORIL MR

pregnancy interaction for DICLORIL MR

lactation interaction for DICLORIL MR

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Dicloril mr 250mg/50mg/325mg tablet may cause excessive drowsiness and calmness with alcohol.
Taking diclofenac with alcohol can increase your risk of stomach bleeding.
UNSAFE
Dicloril mr 250mg/50mg/325mg tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR DICLORIL MR

Chlorzoxazone(250mg)

Uses

Chlorzoxazone is used for muscle relaxation.

How it works

Chlorzoxazone works by acting on the centers in the brain and spinal cord to relieve the muscle stiffness or spasm.

Common side effects

Nervousness, Ovarian hyperstimulation syndrome, Body ache, Dark colored urine, Dizziness, Drowsiness, Liver toxicity, Lightheadedness, Nausea.
Diclofenac(50mg)

Uses

Diclofenac is used in fever, headache, arthralgia, myalgia, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.

How it works

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Common side effects

Paracetamol(325mg)

Uses

Paracetamol is used in fever, headache, pain during menstruation, arthralgia, myalgia, dental pain and post operative pain.

How it works

Paracetamol blocks the release of certain chemical messengers in the brain that is responsible for pain and fever.

Common side effects

Allergic reaction, Liver damage.

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Expert advice FOR DICLORIL MR

  • Do not drive or operate machinery after taking chlorzoxazone.
  • Do not take chlorzoxazone, if you are taking sodium oxybate.
  • Do not consume alcohol while you are taking chlorzoxazone.
  • You should be aware that the urine color changes to orange to purple-red after taking chlorzoxazone, which is normal.
  • Consult your doctor if you develop serious liver complications after administering chlorzoxazone.

Frequently asked questions FOR DICLORIL MR

Chlorzoxazone

Q. Is chlorzoxazone an opiate/ narcotic/ steroid/ controlled substance/ addictive?
No. Chlorzoxazone is mephenesin like centrally acting muscle relaxant that is used to relieve muscle stiffness and pain. It is not a steroid, narcotic, addictive or controlled substance
Q. Does chlorzoxazone be used for recreational purposes?
No, chlorzoxazone or any other drug should not be used for recreational purpose. Use only when prescribed by the doctor
Q. Does chlorzoxazone have aspirin or codeine in it?
No. It does not contain aspirin or codeine
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Q. Does chlorzoxazone induce drowsiness/ weight gain?
It is not known to cause weight gain, but may cause drowsiness. If you experience any such side effects, consult your doctor
Q. Is chlorzoxazone like Vicodin?
No. Vicodin, which contains acetaminophen and hydrocodone, is used to relieve general pain. Chlorzoxazone is a muscle relaxant and different drug altogether
Q. Is chlorzoxazone the same as Soma?
No. Soma caontains carisoprodol, another mephenesin-like centrally acting muscle relaxant. However, it totally different from chlorzoxazone
Q. Can I take chlorzoxazone with tramadol, naproxen or ibuprofen?
No known interaction data is available for these drugs. However, it doesn't mean that the chlorzoxazone can be taken with tramadol, naproxen or ibuprofen. Always consult your doctor regarding the drug usage
Q. Can I take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen?
No. It is advisable not to take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen since interactions have been reported for this combination.

Diclofenac

Q. Is diclofenac a painkiller?
Yes, diclofenac is a painkiller. It is a nonsteroidal anti-inflammatory drug (NSAID) which is used for conditions like rheumatoid arthritis, osteoarthritis, low back pain, migraine attacks, acute gout, ankylosing spondylitis, Control of pain and inflammation in orthopedic, dental and other minor surgery and other painful conditions of bone and muscles. However, it is a prescription drug and should only be taken as per the advice of the doctor.
Q. Is diclofenac safe in asthma?
Diclofenac may worsen the symptoms of asthma in some patients already suffering from asthma. Talk to your doctor before taking diclofenac if you are suffering from asthma or you have a history of asthma.
Q. Is diclofenac banned in India?
No, diclofenac is not banned in India. However, it is a prescription drug and should be taken only when advised by your doctor.
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Q. Is diclofenac a controlled substance?
Diclofenac is not a controlled substance as it does not have the potential for abuse or addiction.
Q. Does diclofenac increase blood pressure?
Diclofenac does not have any effect on blood pressure in normal individuals. However, it can decrease the effect of medicines which are being given for treatment of high blood pressure (antihypertensives). Please consult your doctor before taking diclofenac if you are already suffering from high blood pressure and you are taking medicines for its treatment.
Q. Is diclofenac nephrotoxic (harmful to kidney)?
Diclofenac can interfere with normal kidney function can cause kidney damage when taken at larger doses for a longer duration. Patients should follow the advice of the doctor regarding the dose and duration for which diclofenac should be taken.
Q. Can I take diclofenac for sore throat?
No, diclofenac is not indicated for sore throat. It is a pain-killer.
Q. Can I take diclofenac for period pain?
No, diclofenac is not indicated for dysmenorrhea (pain during menstruation). It is a pain-killer given to reduce pain associated with muscles and bone.
Q. Can I take diclofenac for a toothache?
Diclofenac can be taken for dental pain (toothache). However, please consult your doctor as there could be an underlying infection or other problem which needs to be diagnosed before starting the treatment.
Q. Can I take diclofenac for a headache?
Diclofenac can be taken for headache. However, it is important to know the cause of headache before starting the treatment especially if the frequency is very high. Please consult your doctor.
Q. Can I take diclofenac for back pain?
Diclofenac can be taken for back pain as it can be used for pain involving muscles and bone. However, it is important to know the cause of back pain before starting the treatment. Please consult your doctor.
Q. Can I take diclofenac for neck pain?
Diclofenac can be taken for neck pain if it is related to muscle and bones. However, it should be taken only when advised by your doctor.
Q. Can I take diclofenac for stomach pain?
Diclofenac is not indicated for stomach pain. It is mainly indicated for relieving musculoskeletal pain, consult a doctor if you have stomach pain, as it could be due to some underlying condition which needs to be diagnosed, before taking any medicine, including a painkiller.
Q. Can I take diclofenac for gout?
Diclofenac can be taken to reduce pain in gout, especially when there is acute gout (sudden painful condition). However, its usefulness in chronic gout is limited. Consult your doctor for the right treatment of gout as the medicines should be taken only after it is diagnosed by a doctor.
Q. Can I take diclofenac for sciatica?
Diclofenac is indicated for the relief of pain in low back pain and sciatica. However, you should consult a doctor before taking the drug.
Q. Can I take diclofenac for muscle pain?
Diclofenac can be taken for muscle pain as it helps in reducing pain. It is a prescription drug and should only be taken if when advised by a doctor.
Q. Is diclofenac safe in pregnancy?
Diclofenac can cause harmful effects during pregnancy and to the growth of the fetus (unborn child). It is not recommended to be used during pregnancy. Consult your doctor regarding the use of the drug during pregnancy as you may need to discontinue the medicine or stop breastfeeding.
Q. Is diclofenac safe?
Diclofenac is safe to use if taken in prescribed doses for a prescribed duration as advised by your doctor.
Q. Is diclofenac a sulfa drug?
No, diclofenac is not a sulfa drug. It a non-steroidal anti-inflammatory drug (NSAID).
Q. Is diclofenac safe during breastfeeding?
Diclofenac is known to be passed in the breast milk in small amounts. So, it should not be taken during breastfeeding. Consult your doctor if you are breastfeeding and you have to take this medicine.
Q. Is diclofenac safe in diabetes?
Diclofenac is not known to affect blood sugar levels. However, in diabetics, the drug should be taken carefully as it can increase the risk of cardiovascular diseases also. Consult your doctor before taking diclofenac if you are a diabetic and you have to take it for a long time.
Q. Does diclofenac reduce menstrual flow?
Diclofenac is not known to reduce menstrual flow. If you are experiencing any change in the menstrual flow after taking diclofenac, please consult your doctor.
Q. Does diclofenac reduce fever?
Yes, diclofenac can reduce fever. However, diclofenac in its analgesic (pain-relieving) dose is not indicated for fever. Please consult your doctor for the proper diagnosis and right treatment for your fever.
Q. Does diclofenac induce sleep?
Diclofenac in rare cases can cause somnolence (increased desire to sleep). If you experience any disturbance in your sleep pattern while taking diclofenac, please consult your doctor.
Q. Does diclofenac expire?
Yes, diclofenac like any other medicine expires. It is not recommended to use the drug after its expiry date. Please check the pack before using the medicine.
Q. Does diclofenac cause weight gain?
Diclofenac is not seen to cause weight gain. It can, however, rarely cause edema (swelling) due to fluid retention. If you experience any noticeable change in weight while taking the drug, consult your doctor.
Q. Does diclofenac have aspirin in it?
No, diclofenac does not contain aspirin. They are different medicines belonging to the same class of nonsteroidal anti-inflammatory drugs (NSAIDs).
Q. Does diclofenac contain paracetamol?
No, diclofenac does not contain paracetamol. They are different medicines belonging to the same class of nonsteroidal anti-inflammatory drugs (NSAIDs).
Q. Does diclofenac contain ibuprofen?
No, diclofenac does not contain ibuprofen. They are different medicines belonging to the same class of nonsteroidal anti-inflammatory drugs (NSAIDs).
Q. Does diclofenac cause constipation?
Constipation is a very rare side effect with diclofenac. If you experience constipation while taking diclofenac, please consult your doctor.
Q. Can I take diclofenac with etoricoxib?
Both diclofenac and etoricoxib are the non-steroidal anti-inflammatory drug (NSAIDs) and can be given together. No interactions have been reported between the two. However, there are interactions reported between diclofenac and other NSAIDs. Please consult your doctor before taking the two medicines together.
Q. Can I take diclofenac with paracetamol?
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like paracetamol, it can increase the risk of stomach bleeding and ulceration. Consult your doctor before taking the two medicines together.
Q. Can I take diclofenac with naproxen?
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like naproxen, it can increase the risk of stomach bleeding and ulceration. Consult your doctor before taking the two medicines together.
Q. Can I take diclofenac with ibuprofen?
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like ibuprofen, it can increase the risk of stomach bleeding and ulceration. Consult your doctor before taking both the drugs together.
Q. Can I take diclofenac with hydrocodone?
No interactions have been clinically observed between diclofenac and hydrocodone. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take diclofenac with amoxicillin?
Diclofenac and amoxicillin are not known to have any clinically meaningful interactions when taken together. However, interactions may occur. Please consult your doctor before taking both the medications together.
Q. Can I take diclofenac with meloxicam?
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID), and when given along with other NSAIDs like meloxicam, it can increase the risk of stomach bleeding and ulceration. Consult your doctor before taking both the drugs together.

Paracetamol

Q. Can I take Paracetamol with vitamin B complex?
Yes, Paracetamolcan be taken with vitamin B-complex preparations. They have been used together in the treatment of acute and painful diseases affecting nerves like trigeminal neuralgias, post-operative pain, etc. Paracetamol helps to relieve pain and vitamin B-complex corrects the deficiency that might be causing your symptoms.
Q. Is Paracetamol use associated with Helicobacter pylori infection?
No, Paracetamol use is not associated with Helicobacter pylori infection. Painkiller drugs can increase the acid secretion in the stomach, aggravate the symptoms of this infection and the risk of stomach and the intestine ulcer. However, this risk is minimum with paracetamol as compared to other pain killers.
Q. Can I take Paracetamol with fexofenadine?
Yes, Paracetamol can be taken safely with fexofenadine. No drug-drug interactions or any harmful effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore-throat and other allergic or viral diseases. Fexofenadine helps to relieve sneezing, runny nose, itchy throat, or eyes and Paracetamol helps to relieve pain or fever.
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Q. Can I take paracetamol with warfarin?
Paracetamol is safe to use occasionally with warfarin as other painkillers like ibuprofen and aspirin can increase the risk of bleeding. However, on a long-term use, paracetamol can also increase the risk of bleeding. Talk to your doctor before taking them together as you may need to be monitored regularly.
Q. Can I take paracetamol with tamsulosin?
Paracetamol can be taken with Tamsulosin. No harmful side effects or other interactions have been seen when they are taken together. Tamsulosin is an alpha adrenergic receptor blocker used to treat symptoms of benign prostatic hyperplasia.
Q. Can I take Paracetamol with cetirizine?
Yes, Paracetamol can be taken safely with cetirizine. No drug-drug interactions or any harmful effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore throat and other allergic or viral diseases. Cetirizine helps to relieve sneezing, runny nose, itchy throat, or eyes and Paracetamol helps to relieve pain or fever.
Q. Can I take paracetamol with ibuprofen?
Yes, paracetamol can be taken with ibuprofen. Both help to relieve pain and fever and ibuprofen also decreases inflammation and swelling. However, both increase the acid secretion in the stomach and can cause acid reflux, heartburn, stomach, and intestinal ulcers and gut bleeding on long-term use.
Q. Does Paracetamol use cause weight loss?
Yes, Paracetamol can cause weight loss. This is a minor side effect seen on a regular use of Paracetamol. Other minor side effects include low blood pressure, and allergic reactions.<br>In case you have excessive weight loss without diet or exercise, talk to your doctor as this could be due some underlying condition that needs attention.
Q. Can I take paracetamol for the relief of my headache?
Yes, paracetamol has analgesic (pain-killer) action and it can be taken for the relief of mild to moderate headache. For severe headache and headache not getting relieved with paracetamol, do consult your physician.
Q. Can anyone be allergic to Paracetamol?
Yes, there have been reports of hypersensitivity and allergic reaction with the use of Paracetamol. Symptoms of an allergy include swelling of the face, mouth, and throat, shortness of breath, urticaria, red rash, and severe itching. Stop taking Paracetamol if you have such symptoms and immediately consult your doctor.
Q. Does paracetamol help in relieving a headache?
Yes, Paracetamol has analgesic (pain-killer) action and it is useful in relieving mild to moderate headache. For severe headache and headache not getting relieved with paracetamol, do consult your physician.
Q. How beneficial is to use Paracetamol with diclofenac?
Paracetamol and Diclofenac might be given together in case of fever and pain. Paracetamol has an early onset of action and it helps in relieving the symptoms till diclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.
Q. Can I take paracetamol for stomach pain?
No, paracetamol should not be taken for stomach pain. You must consult your physician for this as the relief of stomach pain can mask some underlying disease problem that needs attention.
Q. Can I take paracetamol with aceclofenac?
Paracetamol and Aceclofenac might be given together in case of fever and pain. Paracetamol has an early onset of action and it helps in relieving the symptoms till Aceclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.
Q. Does paracetamol treat sore-throat, flu or cold?
Paracetamol does not treat sore-throat, flu or cold but it can help in relieving fever and body aches associated with these conditions.
Q. Can I take paracetamol with codeine?
Paracetamol and codeine can be taken together. No drug-drug interactions or any harmful effects have been reported when they are used together. They are commonly given together for the relief of mild to moderate pain due to different reasons.
Q. Does paracetamol help a cough?
No, paracetamol does not help in the relief of cough but it can help in relieving associated fever and body aches.
Q. Why most cold or flu drugs contains paracetamol?
Paracetamol has both fever relieving and painkiller properties. Most people suffering from common cold or flu experience low-grade fever, muscle pain and overall feeling of tiredness. Paracetamol reduces these symptoms, so, it is commonly a part of cold or flu medicines.
Q. Does paracetamol contain alcohol?
No, paracetamol does not contain any alcohol.
Q. Can I take paracetamol with amoxicillin?
Paracetamol and amoxicillin can be taken together. Amoxicillin is an antibiotic and is used to treat bacterial infections. Paracetamol is given along with for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Does paracetamol have side effects?
Paracetamol is quite safe for short term use. It has side effects if taken in more than the dose advised. Immediately consult a doctor if there is nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice as it could be due to an overdose of paracetamol.
Q. Q. Is paracetamol safe to use?
Paracetamol is safe to use in the dose as advised by the doctor. Use in more than recommended doses can do serious harm.
Q. Is it safe to take paracetamol with erythromycin?
Paracetamol and Erythromycin can be taken together. Erythromycin is an antibiotic and is used to treat bacterial infections. Paracetamol is given along with for the relief of associated fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is paracetamol an antibiotic?
Paracetamol is not an antibiotic. It's an analgesic (pain-killer) and anti-pyretic (for the relief of fever) while an antibiotic is useful in the treatment of infections.
Q. Can I take paracetamol with metronidazole?
Paracetamol and Metronidazole can be taken together. No drug-drug interactions or any harmful effects have been reported when used together.
Q. Can I take paracetamol with homeopathic medicine?
Ask your doctor before taking paracetamol with homeopathic medicine as there is no data available on this.
Q. Is it safe to take Paracetamol with Tramadol?
Yes, Paracetamol can be taken with Tramadol. No drug-drug interactions have been reported when they are used together. They are used together for moderate to severe pain in various diseases and their use is associated with common side effects like nausea, dizziness, and sleepiness.
Q. Can I take Paracetamol with Azithromycin?
Paracetamol and Azithromycin can be taken together. Azithromycin is an antibiotic and is used to treat bacterial infections. Paracetamol is given along with for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I take paracetamol for period pains?
Yes, Paracetamol is a pain killer and can help in the relief of mild to moderate pain associated with periods also known as dysmenorrhoea (painful menstruation).
Q. Is it safe to take Paracetamol with Naproxen?
Yes, paracetamol can be taken with Naproxen. Both are painkillers and belong to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and are used to relieve pain and fever. However, long-term use affects the stomach lining and increase acid secretion which can lead to side effects like acid reflux, heartburn, stomach, and intestinal ulcers and bleeding.
Q. Can paracetamol make babies/ toddlers sleep when used for teething pain?
Paracetamol helps to relieve teething pain in infants and children but it does not make them sleep. The child may go to sleep once the pain is relieved.
Q. Can a patient with high blood pressure take paracetamol?
Occasional use of Paracetamol is safe in patients with high blood pressure. However, if it is to be taken for a long time, you must talk to your doctor. Paracetamol belongs to the group of painkillers called non-steroidal anti-inflammatory drugs (NSAIDs) and these drugs can decrease the action of medicines taken by the patient for control of high blood pressure.
Q. Does Paracetamol interact with vitamin C?
Vitamin C can be taken with Paracetamol. However, vitamin C increases the blood levels of other drugs similar to Paracetamol, so it is advised to talk to your doctor if you have to take both these medicines for a long-term.
Q. What happens if you take an overdose of Paracetamol?
Overdose of Paracetamol can cause potentially life-threatening liver damage, which is the most serious side effect. Early symptoms may include nausea, vomiting, profuse sweating, and general tiredness. Kidney damage, decreased platelet count and coma may also occur. Immediately consult a doctor or consult an emergency in the case of suspected overdosage.
Q. What is the difference between Paracetamol and Ibuprofen?
Both Paracetamol and ibuprofen help to relieve mild to moderate pain and fever. Ibuprofen also helps to decrease redness and swelling because of the anti-inflammatory action while Paracetamol has no anti-inflammatory action. But the use of Paracetamol is much safer as it causes fewer stomach upset, ulcers, and bleeding than Ibuprofen.
Q. Can I take Paracetamol with hyoscine?
Yes, Paracetamol and hyoscine can be taken together. Hyoscine is used to relieve pain and cramps of the stomach, gut, urinary bladder and urinary tract while Paracetamol is used to relieve mild to moderate pain of a headache, toothache, muscle pain, joint pain, and fever. Together they can be advised by a doctor for painful conditions of the gut and urinary tract.
Q. Can I take Paracetamol with erythromycin?
Paracetamol and Erythromycin can be taken together. Erythromycin is an antibiotic and is used to treat bacterial infections. Paracetamol is given along with for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can I use Paracetamol after the caesarean section?
Yes, Paracetamol can be taken after a caesarean section to relieve pain. It is a very safe drug for pain relief and has minimal side effects at low doses. A very small amount of drug passes into breast milk that should not affect your baby. Paracetamol use also helps to lower the dose of other painkillers.
Q. Can I take Paracetamol with Betahistine?
Paracetamol can be taken with Betahistine. There are no reported drug-drug interactions or harmful effects when they are used together.
Q. Q. Can I take Paracetamol with rabeprazole?
Paracetamol can be taken with Rabeprazole . Rabeprazole is used to prevent painkiller (NSAIDs) induced stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.

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Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)