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Depran 5 Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 07 Apr 2026 | 02:54 PM (IST)
Depran 5 Tablet is a prescription medicine used to treat anxiety disorders. It is a combination medicine that calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It also works by increasing the level of a chemical messenger in the brain, which improves mood.
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General Information

Contains

Clonazepam (0.5mg)+ Escitalopram Oxalate (5mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 25°C
The content is shown in English
Depran 5 Tablet image
Depran 5 Tablet image
Depran 5 Tablet image
Depran 5 Tablet image
Depran 5 Tablet image
Depran 5 Tablet image

Product introduction

Depran 5 Tablet can be taken with or without food. However, it is advised to take it at the same time each day, as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor, as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly, as it may cause withdrawal symptoms.


Some common side effects of this medicine include delayed ejaculation, low sexual desire, vomiting, memory impairment, depression, and confusion. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may cause weight gain or weight loss, depending on person to person. To prevent weight gain, you can eat a balanced diet and exercise regularly. On the other hand, weight loss can be prevented by increasing food portions in your diet. It is important to inform your doctor if you develop any unusual mood changes, as it can cause suicidal thoughts.


Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Depran Tablet

Benefits of Depran Tablet

Treatment of Anxiety disorder
Depran 5 Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Generalised Anxiety Disorder. Depran 5 Tablet will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

Side effects of Depran Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Depran
  • Delayed ejaculation
  • Confusion
  • Vomiting
  • Memory impairment
  • Nausea
  • Diarrhea
  • Uncoordinated body movements
  • Drowsiness
  • Tiredness
  • Anorgasmia (decreased orgasm)
  • Low sexual desire

How to use Depran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depran 5 Tablet may be taken with or without food.

How Depran Tablet works

Clonazepam and escitalopram have anxiety-lowering and mood-enhancing effects. Clonazepam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) that increases the levels of serotonin, a chemical messenger that improves mood.

Quick tips

  • Depran 5 Tablet is prescribed for the treatment of anxiety disorder.
  • You may feel that Depran 5 Tablet is not helping you straightaway. This is because it can take a few weeks before you feel the full benefit. It is important that you continue to take it, even if it takes a little while for your condition to improve.
  • If you develop any depressing or suicidal thoughts or ideas, you should let your doctor know about them as soon as possible.
  • You might experience low sexual desire after taking Depran 5 Tablet. Talk to your doctor if it troubles you.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Depran 5 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

UNSAFE
Depran 5 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Depran 5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Depran 5 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Depran 5 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Depran 5 Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Liver

Liver

UNSAFE
Depran 5 Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Depran 5 Tablet is a combination of two medicines: Clonazepam and Escitalopram. This combination is used to treat anxiety disorders. Clonazepam works by decreasing abnormal electrical activity in the brain. Escitalopram works by increasing the amount of serotonin, a natural substance in the brain that helps to improve mood.
Depran 5 Tablet may make you feel drowsy or you may fall asleep suddenly during your routine activities like watching television, talking, eating or riding in a car. You might not feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. Inform your doctor if you experience such symptoms.
No, taking higher than the recommended dose of Depran 5 Tablet can lead to increased chances of side effects and toxicity. If you are experiencing increased severity of your symptoms that is not relieved by the recommended doses, please consult your doctor for re-evaluation.
No, you should not stop taking Depran 5 Tablet even if you feel well. Continue taking your medicine as advised. Your doctor may lower your dose gradually if your symptoms are improving.
Keep Depran 5 Tablet in a container that is tightly closed and out of children's reach. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Unneeded medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

Fact Box

Habit Forming

Yes

Therapeutic Class

NEURO CNS

References

  1. Clonazepam. Boucherville, Québec: Sandoz Canada Inc.; 2018. [Accessed 23 Apr. 2019] (online) Available from:
  2. Escitalopram. Copenhagen, Denmark: H Lundbeck A/S; 2016. [Accessed 23 Apr. 2019] (online) Available from:
  3. DailyMed. Escitalopram Oxalate. [Accessed 23 Apr. 2019] (online) Available from:
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User feedback

Once A Day
80%
Once A Week
20%
Anxiety disorder
87%
Others
13%
Excellent
67%
Average
26%
Poor
7%
No Side Effect
60%
Uncoordinated body movements
10%
Vomiting
10%
Nausea
10%
Confusion
10%
With food
62%
With or without food
38%
Expensive
46%
Average
33%
Not Expensive
21%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

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