Dep Tablet

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 21 Sep 2025 | 05:43 PM (IST)

Dep Tablet is a prescription medicine used to treat schizophrenia. It is a combination medicine that calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It also blocks the action of a chemical messenger in the brain that affects thoughts and mood.

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General Information

Contains

Chlordiazepoxide (10mg)+ Imipramine (25mg)+ Trihexyphenidyl (0.5mg)+ Trifluoperazine (1.5mg)

Marketer

Elite Pharma Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Dep Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop this medicine suddenly as it may cause withdrawal symptoms.

Some common side effects of this medicine include nausea, dryness in mouth, sedation, urinary retention, blurred vision, and confusion. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your drowsiness. This medicine can lead to weight gain and increase blood sugar levels. It is advisable to avoid high-calorie food, eat a healthy balanced diet and exercise regularly and monitor blood sugar regularly.

Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Dep Tablet

Schizophrenia

Benefits of Dep Tablet

Schizophrenia
Schizophrenia is a chronic and severe mental disorder that affects how a person thinks, feels, and behaves. It can cause symptoms such as delusions, hallucinations, disorganized speech, lack of motivation, and emotional flatness. Dep Tablet is used to manage schizophrenia by helping to stabilize mood, reduce psychotic symptoms, and improve overall mental function. It supports clearer thinking, emotional balance, and better participation in daily activities, contributing to improved quality of life for those affected.

Side effects of Dep Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dep

Nausea
Dryness in mouth
Sedation
Weight gain
Confusion
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Memory impairment
Urinary retention
Increased prolactin level in blood
Dizziness
Uncoordinated body movements
Slow heart rate
Depression
Tiredness
Blurred vision
Nervousness
Constipation

How to use Dep Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dep Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Dep Tablet works

Dep Tablet is a combination of four medicines: Chlordiazepoxide, Imipramine, Trihexyphenidyl and Trifluoperazine. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. Imipramine is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Trihexyphenidyl is an anticholinergic which works on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Quick tips

Dep Tablet is used for the treatment of schizophrenia.
It is better to take it at night as this medicine may produce drowsiness or sleepiness.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any antidepressants.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Dep Tablet may affect the levels of sugar in your blood.
This medicine can make your skin more sensitive to sunlight than usual. Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Dep Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Dep Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Dep Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Dep Tablet may cause side effects which could affect your ability to drive.
Dep Tablet make u feel dizzy, drowsy or can cause blurred vision. This may affect your driving ability.

Kidney

CAUTION

Dep Tablet should be used with caution in patients with kidney disease. Dose adjustment of Dep Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Dep Tablet should be used with caution in patients with liver disease. Dose adjustment of Dep Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is recommended while you are taking this medicine.

Fact Box

Habit Forming

Yes

Therapeutic Class

NEURO CNS

References

Trifluoperazine. Leeds, Yorkshire: Rosemont Pharmaceuticals Limited; 2008 [revised 27 Nov. 2018]. [Accessed 22 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Elite Pharma Pvt Ltd
Address: 1210/11/12, g i d c phase-iii, vatva, ahmedabad, gujarat 382445

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Dep Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Dep Tablet

Benefits of Dep Tablet

Side effects of Dep Tablet

How to use Dep Tablet

How Dep Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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