Demfo 120mg Capsule

Dimethyl fumarate (120mg)

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Demfo 120mg Capsule is a medicine used in the treatment of multiple sclerosis (MS). It works by suppressing the inflammation and immune system that causes nerve damage in MS and helps reduce the worsening of the condition. However, it is not a cure for MS.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 22 May 2026 | 03:59 PM (IST)

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Gurgaon

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General Information

Contains

Dimethyl fumarate (120mg)

Marketer

Dr Reddy's Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Demfo 120mg Capsule should be taken as advised by the doctor. You may take it with food to avoid an upset stomach. You may need to get regular blood and urine tests to monitor your blood cells, and kidney and liver function during treatment with this medicine. Take it regularly to get the most benefit from it. To help you remember, take it at the same time each day and do not stop taking until you have completed your dose.

Some common side effects of this medicine include flushing, abdominal pain, diarrhea, nausea, vomiting, indigestion, gastritis, increased liver enzymes, and rash. If you experience any of these side effects that do not go away or get worse, let your doctor know. They may be able to suggest ways to prejudice or prevent them.

Before using this medicine, tell your doctor if you have low white blood cell counts or an infection. Let your doctor also know of all the medical conditions and about the medicines you are taking to make sure it is safe for you. Pregnant and breastfeeding women should consult their doctor first before using this medicine as it may cause harmful effects to the developing baby.

Uses of Demfo Capsule

Treatment of Multiple sclerosis (MS)

Benefits of Demfo Capsule

Treatment of Multiple sclerosis (MS)
Multiple sclerosis is a long-term condition in which the body’s immune system mistakenly attacks the protective covering of nerves, leading to problems with movement, vision, and coordination. Demfo 120mg Capsule helps lower the frequency of relapses and slows down the progression of nerve damage. This supports better control of MS symptoms and helps patients maintain daily functioning and quality of life.

Side effects of Demfo Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Demfo

Vomiting
Diarrhea
Nausea
Abdominal pain
Indigestion
Stomach inflammation
Increased liver enzymes
Rash
Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Demfo Capsule

Take this medicine in the dose and duration as advised by your doctor. Demfo 120mg Capsule should be taken with or after food.

How Demfo Capsule works

Demfo 120mg Capsule is an Nrf2 activator. It works by suppressing inflammation and immune response that cause nerve damage in multiple sclerosis.

All substitutes for Demfo 120mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Tecfidera 120mg Capsule

by Eisai Pharmaceuticals India Pvt Ltd

₹1355.86/capsule

1629% costlier

Quick tips

Demfo 120mg Capsule helps treat multiple sclerosis.
Take it with food to avoid an upset stomach.
Do not chew, crush or break the tablets as they have a special coating to help prevent irritation of your stomach.
Do not consume alcohol while taking this medicine as it may worsen the side effects.
Your doctor may get regular blood and urine tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Do not take Demfo 120mg Capsule if you are pregnant or breastfeeding. Use a reliable contraceptive method to prevent pregnancy.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Demfo 120mg Capsule.

Pregnancy

CONSULT YOUR DOCTOR

Demfo 120mg Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Demfo 120mg Capsule during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Demfo 120mg Capsule does not usually affect your ability to drive.

Kidney

CAUTION

Demfo 120mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Demfo 120mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Demfo 120mg Capsule used for?

Demfo 120mg Capsule is used to treat relapsing‑remitting multiple sclerosis (MS) in adults and children aged 13 years and older. It helps reduce the frequency of MS relapses and may slow disease progression.

Who should not take Demfo 120mg Capsule?

Individuals should not take Demfo 120mg Capsule if they are allergic to dimethyl fumarate or any ingredient in the medicine, or if they have suspected or confirmed progressive multifocal leukoencephalopathy (PML), a rare and serious brain infection.

What is PML, and how does Demfo 120mg Capsule relate to it?

Progressive multifocal leukoencephalopathy (PML) is a rare, potentially fatal brain infection caused by a virus. Cases have been reported in patients taking Demfo 120mg Capsule, especially those with low white blood cell counts (lymphopenia). Your doctor will monitor your blood counts regularly to reduce this risk.

Can Demfo 120mg Capsule cause low white blood cell counts?

Yes. Demfo 120mg Capsule can lower lymphocyte counts, which may increase infection risk. Your doctor will check your blood before starting treatment and every 3 months during therapy. Treatment may be stopped if your counts drop too low for more than 6 months.

What serious side effects of Demfo 120mg Capsule require immediate medical attention?

Serious side effects of Demfo 120mg Capsule include PML (new weakness, vision changes, confusion, personality changes), severe allergic reactions (swelling, breathing trouble, rash), or symptoms of liver problems (yellowing skin or eyes, severe stomach pain).

Are there any kidney or liver concerns with Demfo 120mg Capsule?

Yes. Demfo 120mg Capsule may cause kidney changes and liver enzyme elevations. Your doctor will check your kidney and liver function before you start and periodically during treatment. Use with caution if you have severe kidney or liver disease.

Can I get infections like shingles while taking Demfo 120mg Capsule?

Yes. Herpes zoster (shingles) infections have been reported while taking Demfo 120mg Capsule. Tell your doctor immediately if you develop painful blisters, rash, burning skin, or flu‑like symptoms, especially if you have low white blood cell counts.

Can Demfo 120mg Capsule cause flushing or stomach problems?

Yes. Flushing (redness, warmth) and gastrointestinal side effects (diarrhea, nausea, stomach pain) are very common, especially in the first month of Demfo 120mg Capsule treatment. Taking the medicine with food can help reduce these effects. Your doctor may temporarily lower the dose.

What is Fanconi syndrome, and can Demfo 120mg Capsule cause it?

Fanconi syndrome is a rare kidney disorder that has been reported with fumarate‑containing medicines such as Demfo 120mg Capsule. Symptoms include increased urination, thirst, muscle weakness, or bone pain. Contact your doctor if you notice these signs, so testing can be done.

Fact Box

Chemical Class

Fatty acid esters

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Oral Immunomodulators (Multiple Sclerosis)

References

Tecfidera. Dimethyl fumarate. [Accessed 24 Jan. 2019] (online) Available from:
Dimethyl fumarate. Cambridge: Biogen Idec Inc; 2013. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Dimethyl fumarate [Summary of Product Characteristics]. Badhoevedorp, The Netherlands: Biogen Netherlands B.V.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Vendor Details

Country of origin: India

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Demfo 120mg Capsule

Demfo 120mg Capsule

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Demfo Capsule

Benefits of Demfo Capsule

Side effects of Demfo Capsule

How to use Demfo Capsule

How Demfo Capsule works

All substitutes for Demfo 120mg Capsule

Tecfidera 120mg Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Demfo 120mg Capsule used for?

Who should not take Demfo 120mg Capsule?

What is PML, and how does Demfo 120mg Capsule relate to it?

Can Demfo 120mg Capsule cause low white blood cell counts?

What serious side effects of Demfo 120mg Capsule require immediate medical attention?

Are there any kidney or liver concerns with Demfo 120mg Capsule?

Can I get infections like shingles while taking Demfo 120mg Capsule?

Can Demfo 120mg Capsule cause flushing or stomach problems?

What is Fanconi syndrome, and can Demfo 120mg Capsule cause it?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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