Definate LF Syrup is a combination medicine that is prescribed to treat malaria. It fights against the infection by preventing the growth of the parasites inside the body.
Definate LF Syrup is a prescription medicine. It is to be taken with food and take it at a fixed time regularly. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. A missed dose should be taken as soon as you remember. The course of the treatment should be completed for better efficacy.
Some common side effects of this medicine are headaches, loss of appetite, weakness, pain in muscles, and joint pain. You may also feel dizzy, thus it is advised not to drive or operate machinery. To overcome dizziness you should drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately.
Before taking this medicine, you should tell your doctor if you are taking any medication for any health conditions. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine.
Malaria is a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes. Definate LF Syrup is an antimalarial medicine and is used to treat malaria. It kills the infection-causing parasite and stops the further spread of the infection in the body. Do not use this medicine for treating any other condition without consulting your doctor.
Side effects of Definate LF Syrup
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Definate LF
Muscle pain
Joint pain
Headache
Loss of appetite
Dizziness
Weakness
How to use Definate LF Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Definate LF Syrup should be taken with or after food.
How Definate LF Syrup works
Definate LF Syrup is a combination of two antiparasitic medicines: Arteether and Lumefantrine, which treats malaria. These medicines work by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Definate LF Syrup. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Definate LF Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Definate LF Syrup during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Definate LF Syrup may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Definate LF Syrup should be used with caution in patients with severe kidney disease. Dose adjustment may be needed. No dose adjustment is recommended in patients with severe kidney disease.
Liver
CAUTION
Definate LF Syrup should be used with caution in patients with severe liver disease. Dose adjustment may be needed. No dose adjustment is recommended in patients with severe liver disease.
What if you forget to take Definate LF Syrup?
If you miss a dose of Definate LF Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Take Definate LF Syrup with a high-fat meal (like milk or curd-based food) to improve absorption and enhance effectiveness.
Complete the full course exactly as prescribed, even if symptoms improve early, to fully clear the malaria infection.
Avoid taking Definate LF Syrup with grapefruit or grapefruit juice, as it may interfere with how the medicine works in your body.
If you feel dizzy or weak, rest and stay hydrated, as these can be common early effects while your body fights malaria.
If you vomit within 1 hour of taking the tablets, take another dose.
Let your doctor know if you have any history of heart rhythm problems, as this medicine may affect heart activity
Fact Box
Habit Forming
No
Therapeutic Class
ANTI MALARIALS
Patient concerns
I took acetate-sp and definate tablets on advise of my regular doctor I had a little swollen knee doctor told it may be due to squat I had ligament operated 8 years back after taking tablets I got excessive sweating and dizzy feeling a bit faster heart bits is it side effects of tablets
Dr. Akshat Goel
Orthopaedics
It may be because of Deflazacort tablets Please apply Ice Packs to the affected knee every 4 hours to reduce swelling and Take Tab Flotrip-forte thrice daily for next 5 days. Continue Aceclofenac tablets if pain persists
Today is third day and I am taking dolo 650 and azithromycin 500 from last two days. Still in the morning fever is around 100.9. Any tests are required? Please suggest.
I have fever since last four days, I was prescribed zifi 200 and zerodol p by my doctor, but I started getting rashes, reactions, so the doctor stopped the meds, and said to have crocin only, now fourth day is over, fever comes down after having crocin then comes back again. Body ache, and headache is there, fever reaches 103, 103.8 easily every morning, have pain in my eyes also. Had zathrin 250 in the morning and at night today with crocin, my doctor suggested it on phone. What do I have? And why am I not getting better? What medication should I take?
Definate LF Syrup is used to treat uncomplicated malaria caused by Plasmodium falciparum. This medicine helps quickly reduce the number of malaria parasites in the blood.
Should I take Definate LF Syrup with food?
Yes, you should take Definate LF Syrup with food. Definate LF Syrup works better when taken with food or a milky drink, as it improves the absorption of the medicine.
Who should not take Definate LF Syrup?
Individuals should not take Definate LF Syrup if they are allergic to artemether, lumefantrine, or any ingredients present in Definate LF Syrup. It should also be avoided in people with heart rhythm problems or those taking other medicines that affect heart rhythm (QT-prolonging drugs). Use is not recommended in cases of severe kidney or liver disease. Definate LF Syrup should not be used during the first trimester of pregnancy. It is also contraindicated with strong medications that affect CYP3A4, such as rifampin, phenytoin, or St. John’s wort.
Can Definate LF Syrup affect my heart?
Yes, Definate LF Syrup can affect heart rhythm by prolonging the QT interval. If you have heart conditions or take other QT-prolonging medicines, talk to your doctor before using this medication.
What are the serious side effects of Definate LF Syrup?
The serious side effects of Definate LF Syrup may include irregular heartbeat, allergic reactions (rash, swelling, difficulty breathing), liver problems, and/or seizures or confusion (rare). Reach out to your doctor right away if you notice any of these symptoms.
What should I do if I vomit after taking Definate LF Syrup?
If you vomit within 1 to 2 hours of taking Definate LF Syrup, you should repeat the dose. If you vomit again, your doctor might need to switch to another antimalarial treatment.
What warning signs should I watch for during Definate LF Syrup treatment?
During Definate LF Syrup treatment, seek immediate medical attention if you experience severe dizziness or fainting, irregular heartbeat, severe nausea/vomiting, dark urine, yellowing of skin/eyes, unusual bleeding or bruising, and severe headache with confusion.
How do I know if Definate LF Syrup is working?
You can tell Definate LF Syrup is effective if you notice improvements such as reduced fever within 24 to 48 hours, symptoms (chills, body aches) lessen, appetite improves, energy levels increase, etc. Even if you feel better, complete the full course of treatment as prescribed to ensure the infection is fully treated.
What precautions should I take during Definate LF Syrup treatment?
Important precautions during Definate LF Syrup treatment include avoiding driving if you feel dizzy, staying hydrated, completing the full course, reporting unusual symptoms, avoiding strenuous activity, and getting adequate rest.
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References
Lumefantrine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Mar. 2015]. [Accessed 30 Mar. 2019] (online) Available from:
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