Defenac MR Tablet

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Lupin Ltd

Composition for Defenac MR Tablet

iconPrescription Required

Primarily used for

Fever, Muscle relaxation, Headache
Potentiallyunsafewith
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Alcohol
56.25
₹5.62/Tablet
10 tablets in 1 strip
SOLD OUT

Medicine Overview of Defenac MR Tablet

uses

Uses of Diclofenac

Diclofenac is used in fever, headache, arthralgia, muscle pain, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.
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Side effects of Diclofenac

Common

Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.

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How to use Diclofenac

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defenac MR Tablet is to be taken with food.
This will help to avoid acidity and heartburn.

How Defenac MR Tablet works

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (redness and swelling), fever and pain.
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Uses of Chlorzoxazone

Chlorzoxazone is used for muscle relaxation
It relieves painful spasms of the skeletal muscles.
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Side effects of Chlorzoxazone

Common

Sleepiness, Dry mouth.

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How to use Chlorzoxazone

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defenac MR Tablet is to be taken with food.
This will help to avoid acidity and heartburn.

How Defenac MR Tablet works

Chlorzoxazone is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles.

In Depth Information on Defenac MR Tablet

Expert advice for Diclofenac

  • It should be taken with food or milk to avoid getting an upset stomach.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • Diclofenac can raise a risk of blood clots, heart attack, or a stroke.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Expert advice for Chlorzoxazone

  • Chlorzoxazone can increase the effects of other CNS depressants (alcohol, barbiturates) medicine.
  • Avoid consuming alcohol when taking the Chlorzoxazone, as it may cause excessive drowsiness and calmness.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Defenac MR Tablet related warnings
Special precautions for Defenac MR Tablet
Alcohol
CAUTION
Taking diclofenac with alcohol can increase your risk of stomach bleeding.
Pregnancy
WEIGH RISKS VS BENEFITS
Defenac MR Tablet is unsafe to use during pregnancy.

There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
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Lactation
No information is available on the use of Defenac MR Tablet
during lactation. Please consult your doctor.
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Driving
Defenac MR Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Defenac MR Tablet should be used with caution in patients wi
th kidney disease. Dose adjustment of Defenac MR Tablet may be needed. Please consult your doctor.
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Liver
CAUTION
Defenac MR Tablet should be used with caution in patients with liver disease. Dose adjustment of Defenac MR Tablet may be needed. Please consult your doctor.

Regular monitoring of liver function tests is recommended in patients with liver disease if this medicine is to be taken for a long time.
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Patient Concerns

Frequently asked questions about Defenac MR Tablet

Frequently asked questions about Diclofenac

Q. Can Diclofenac be used along with warfarin?
No. Using Diclofenac together with warfarin can increase the risk of serious bleeding from the stomach (Higher than users of either drug alone). Inform your doctor before starting these medications.
Q. Is Diclofenac a painkiller?
Yes. Diclofenac is a pain killer. In fact, it belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.
Q. Is Diclofenac a narcotic?
No, Diclofenac is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.
Q. Can I use Diclofenac along with vitamins?
Yes, Diclofenac can be taken with vitamins. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can Diclofenac be used for the treatment of hepatitis?
No, Diclofenac is not approved for the treatment of hepatitis. Hepatitis is a condition where the liver is inflamed. Diclofenac can, in fact, cause harm to the liver as a side effect.
Q. Can Diclofenac be used after C-section?
Yes, Diclofenac is a pain killer. C-section is the short name for Cesarean Section which is an operative procedure to deliver the baby through the mother's abdomen and uterus. Diclofenac can be used to treat the pain that may occur after the operation.
Q. Can I take Diclofenac along with misoprostol?
Yes. It can be taken together. Misoprostol protects the stomach from irritating gastric effects of Diclofenac. The combination of medication is used to treat arthritis in patients at high risk of getting stomach/intestinal ulcers and complications from the ulcers (such as bleeding).
Q. Can I take Diclofenac while I am on thyroxine?
Yes, Diclofenac can be taken with thyroxine. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Why Diclofenac should be stopped before surgery?
Since Diclofenac has been shown to have blood thinning effects, it can increase the risk of bleeding. Therefore, it is stopped before surgery to prevent excessive loss of blood.
Q. What are the contraindications for Diclofenac?
Diclofenac should not be used if there is an allergic reaction (hypersensitivity) to it, or other pain killers, active ulcer in the stomach, bleeding from the stomach, history of severe heart failure, liver failure, kidney failure and or heart attack.
Q. Can Diclofenac affect the chance of conceiving?
Yes. Diclofenac can sometime cause reversible infertility. Diclofenac by its mechanism of action, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Why does Diclofenac cause an ulcer?
Diclofenac can cause damage to the lining cells of the stomach by several mechanisms, including the irritant effect on the cells, breaking of the protective barrier properties of lining cells, suppression of prostaglandin production of the stomach, reduction of stomach mucosal blood flow and interference with the repair of superficial injury of the stomach lining.
Q. Why is Diclofenac contraindicated in asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory drugs (NSAID) like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Is Diclofenac good for back pain?
Yes, Diclofenac has been found to be effective to reduce back pain. Diclofenac is a pain killer that belongs to the NSAIDs (Non-Steroidal Anti-Inflammatory) class. Other NSAIDs have also been found to be useful in back pain eg. Ibuprofen and Naproxen.
Q. Can I use Diclofenac during my fever treatment?
Yes, Diclofenac can reduce fever. However, commonly used to reduce the pain, particularly that which is seen with Osteoarthritis, Rheumatoid Arthritis and Ankylosing spondylitis.
Q. Can I use Diclofenac to treat a sore throat?
Sore throat is mostly caused by bacteria so antibiotics are given to treat a sore throat whereas Diclofenac is a pain killer so it can be given in cases of throat pain associated with it but only under the prescription of a doctor.
Q. Can I use Diclofenac to treat urinary tract infections (UTI)?
Diclofenac can be used to treat the pain associated with urinary tract infection (UTI) but for complete treatment, a course of antibiotics will be required.
Q. Can Diclofenac cause sedation?
Diclofenac is not known to cause sedation. There have been rare, an isolated case report of sedation with the drug.
Q. Can I take Diclofenac for kidney stones?
Yes,Diclofenac can be used to relieve the pain due to kidney stones. However, there is also a risk of kidney damage with Diclofenac as its side effect. It is advised not to take Diclofenac for a prolonged time for this condition without adequate monitoring.
Q. Can I use Diclofenac for the treatment of arthritis?
Yes, Diclofenac is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis, and spondylitis.It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). .
Q. Can I use Diclofenac with diuretics?
No, Diclofenac should not be used with diuretics. Diclofenac reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can I use Diclofenac with mifepristone?
These drugs should not be used together as the effect of mifepristone may be lowered by Diclofenac. Mifepristone is used for medical abortion.
Q. Can I use Diclofenac with lithium?
No.These drugs should not be used together as Diclofenac increases the blood levels of lithium which may further increase the side effects.
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Frequently asked questions about Chlorzoxazone

Q. Is chlorzoxazone an opiate/ narcotic/ steroid/ controlled substance/ addictive?
No. Chlorzoxazone is mephenesin like centrally acting muscle relaxant that is used to relieve muscle stiffness and pain. It is not a steroid, narcotic, addictive or controlled substance
Q. Does chlorzoxazone be used for recreational purposes?
No, chlorzoxazone or any other drug should not be used for recreational purpose. Use only when prescribed by the doctor
Q. Does chlorzoxazone have aspirin or codeine in it?
No. It does not contain aspirin or codeine
Q. Does chlorzoxazone induce drowsiness/ weight gain?
It is not known to cause weight gain, but may cause drowsiness. If you experience any such side effects, consult your doctor
Q. Is chlorzoxazone like Vicodin?
No. Vicodin, which contains acetaminophen and hydrocodone, is used to relieve general pain. Chlorzoxazone is a muscle relaxant and different drug altogether
Q. Is chlorzoxazone the same as Soma?
No. Soma caontains carisoprodol, another mephenesin-like centrally acting muscle relaxant. However, it totally different from chlorzoxazone
Q. Can I take chlorzoxazone with tramadol, naproxen or ibuprofen?
No known interaction data is available for these drugs. However, it doesn't mean that the chlorzoxazone can be taken with tramadol, naproxen or ibuprofen. Always consult your doctor regarding the drug usage
Q. Can I take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen?
No. It is advisable not to take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen since interactions have been reported for this combination.
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