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Composition for DEFENAC MR


food interaction for DEFENAC MR

alcohol interaction for DEFENAC MR

pregnancy interaction for DEFENAC MR

lactation interaction for DEFENAC MR

There is no data available. Please consult doctor before consuming the drug.
Defenac mr tablet may cause excessive drowsiness and calmness with alcohol.
Taking diclofenac with alcohol can increase your risk of stomach bleeding.
Defenac mr tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.




Diclofenac is used in the treatment of painful conditions of joints, lower back pain, sprains or bone fractures, inflammation of joints (frozen shoulder, gout), pain and swelling following skeletal muscle, dental and other minor surgeries. It is also used in treatment of migraine.

How it works

Diclofenac belongs to group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of a certain chemical substance in the body that causes pain, fever, and inflammation.

Common side effects

Epigastric pain, Renal dysfunction, Stomach ulcer, Bleeding, Toxic epidermal necrolysis, Itching


Chlorzoxazone is used to relieve pain and stiffness caused by muscle strains and sprains. 

How it works

Chlorzoxazone is a centrally acting muscle relaxant that causes muscle relaxation and reduces muscle stiffness by blocking nerve impulses (or pain sensations) that are sent to the brain of the central nervous system.

Common side effects

Nervousness, Ovarian hyperstimulation syndrome, Body ache, Dark colored urine, Dizziness, Drowsiness, Liver toxicity, Lightheadedness, Nausea


No substitutes found

Expert advice for DEFENAC MR

  • Diclofenac should be taken with food or immediately after meals.
  • Take the medicine with food to avoid stomach upset.
  • Do not take antacids withh magnesium as they can interact with the drug.
  • Do not take diclofenac, If  you are allergic to diclofenac.
  • Do not drink alcohol while takig this drug.
  • Do not drive or use any tools or machines, if you feel dizzy, tired, have a headache or get blurred vision after taking diclofenac.

Frequently asked questions for DEFENAC MR


Q. Is diclofenac safe?
Diclofenac (also available as voveran, dynapar) is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is diclofenac nephrotoxic?
Diclofenac can interfere with normal kidney function when taken at larger doses for a longer duration. Patients should follow the advice of the doctor regarding its uses.
Q. Is diclofenac safe in asthma?
Diclofenac may worsen the symptoms of asthma in some patients already suffering from asthma. Talk to your doctor before taking diclofenac in asthma.
Q. Is diclofenac banned in India?
Diclofenac is available over-the-counter and it is not banned in India.
Q. Is diclofenac a blood thinner / controlled substance?
Diclofenac is a pain relieving medication and it does not significantly affect the function of platelets in blood; hence it is not a blood thinner. It is not a controlled substance as it does not have the potential for abuse or addiction.
Q. Does diclofenac increase blood pressure?
Diclofenac does not have any effect on blood pressure in normal individuals. However, consult your doctor before taking diclofenac if you are already suffering from high blood pressure or any other heart disease.
Q. Does diclofenac induce sleep?
Diclofenac does not induce sleep.


Q. Is chlorzoxazone an opiate/ narcotic/ steroid/ controlled substance/ addictive?
No. Chlorzoxazone is mephenesin like centrally acting muscle relaxant that is used to relieve muscle stiffness and pain. It is not a steroid, narcotic, addictive or controlled substance.
Q. Does chlorzoxazone be used for recreational purposes?
No, chlorzoxazone or any other drug should not be used for recreational purpose. Use only when prescribed by the doctor.
Q. Does chlorzoxazone have aspirin or codeine in it?
No. It does not contain aspirin or codeine.
Q. Does chlorzoxazone induce drowsiness/ weight gain?
It is not known to cause weight gain, but may cause drowsiness. If you experience any such side effects, consult your doctor.
Q. Is chlorzoxazone like Vicodin?
No. Vicodin, which contains acetaminophen and hydrocodone, is used to relieve general pain. Chlorzoxazone is a muscle relaxant and different drug altogether.
Q. Is chlorzoxazone the same as Soma?
No. Soma caontains carisoprodol, another mephenesin-like centrally acting muscle relaxant. However, it totally different from chlorzoxazone.
Q. Can I take chlorzoxazone with tramadol, naproxen or ibuprofen?
No known interaction data is available for these drugs. However, it doesn’t mean that the chlorzoxazone can be taken with tramadol, naproxen or ibuprofen. Always consult your doctor regarding the drug usage.
Q. Can I take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen?
No. It is advisable not to take chlorzoxazone with hydrocodone/ citalopram/ acetaminophen since interactions have been reported for this combination.


Content on this page was last updated on 03 October, 2014, by Dr. Varun Gupta (MD Pharmacology)