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D-Signoflam Transgel 1
D-Signoflam Transgel 2
D-Signoflam Transgel 3
D-Signoflam Transgel 4
D-Signoflam Transgel 5
D-Signoflam Transgel 6
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D-Signoflam Transgel is a pain-relieving medicine. It is used to treat various conditions such as joint pain, neck pain, sprains, spasms, and others. It works by blocking the release of certain chemicals that cause pain and inflammation.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 09 Sep 2026 | 01:03 AM (IST)
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D-Signoflam Transgel 1
D-Signoflam Transgel 2
D-Signoflam Transgel 3
D-Signoflam Transgel 4
D-Signoflam Transgel 5
D-Signoflam Transgel 6

Product introduction

D-Signoflam Transgel is only for external use. Use it in the dose and duration as prescribed by your doctor. Follow the instructions carefully to get the most benefit. You can also read the package insert for instruction. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Apply it whenever it is needed or as per the doctor’s instruction.

It is generally safe with little or no side effects. However, in some people, it may cause application site reactions such as redness and swelling. These are usually mild and resolve with time. If they do not go away or bother you, you should remove your patch and contact your doctor.

Uses of D-Signoflam Gel

Benefits of D-Signoflam Gel

Pain relief
Pain can occur due to muscle strain, joint problems, sprains, or injuries, making daily activities difficult. D-Signoflam Transgel works on the affected area to reduce pain, swelling, and stiffness. It helps relax sore muscles, ease joint discomfort, and provide quick relief so that movement becomes more comfortable.

Side effects of D-Signoflam Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of D-Signoflam
  • Skin rash
  • Itching
  • Erythema (skin redness)

How to use D-Signoflam Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How D-Signoflam Gel works

D-Signoflam Transgel is a combination of three medicines: Diclofenac diethylamine, Methyl Salicylate, and Alcohol . Diclofenac diethylamine and Methyl Salicylate are non-steroidal anti-inflammatory drugs (NSAIDs) which work by blocking the release of chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling).

Quick tips

  • D-Signoflam Transgel is prescribed to get relief from pain.
  • Apply D-Signoflam Transgel 2-3 times daily or as prescribed by the doctor.
  • Remember to wash your hands after applying D-Signoflam Transgel, unless this is the area being treated.
  • Do not apply D-Signoflam Transgel to large areas of skin or near sensitive areas such as private parts or on broken or injured skin.
  • Avoid contact with the eyes, mouth, nose, and rinse thoroughly in case of accidental contact or seek medical help in case of swallowing.
  • Do not smoke or go near naked flames as D-Signoflam Transgel increases the risk of severe burns.
  • Consult your doctor if you get excessive skin irritation or other unwanted effects.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of D-Signoflam Transgel during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of D-Signoflam Transgel during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established
All

Frequently asked questions

D-Signoflam Transgel is a pain‑relieving medicine used to treat joint pain, neck pain, sprains, spasms, and other types of pain. It works by blocking the chemicals that cause pain and inflammation, and also provides a cooling effect to soothe the affected area.
No. Apply D-Signoflam Transgel only to clean, intact skin. Do not apply to wounds, open injuries, or diseased skin. Avoid the eyes, mouth, and other mucous membranes. Stop use if a skin rash develops.
Although rare, serious side effects of D-Signoflam Transgel can include hives, facial swelling (angioedema), or asthma symptoms. If these occur, stop use and seek medical help. Very rare photosensitivity reactions can also occur, so you should protect treated skin from excessive sunlight.
Non‑occlusive bandages may be used after applying D-Signoflam Transgel, but avoid airtight or occlusive dressings because they can increase absorption and the risk of side effects.
D-Signoflam Transgel is contraindicated in children and adolescents under 14 years of age. For those 14 years and older, follow the directions given by your doctor.
Yes. Local irritation (redness, itching, dermatitis) can occur after using D-Signoflam Transgel. Rarely, blistering or photosensitivity reactions happen. Minimize sun exposure on treated areas and discontinue if significant skin reactions appear.

Fact Box

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
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