Side Effects of Coxter 2E are Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Teary eyes, Increased liver enzymes, Jaundice, Visual impairment, Increased uric acid level in blood, Gout, Peripheral neuropathy (tingling and numbness of feet and hand).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coxter 2E Tablet is to be taken empty stomach. Avoid Coxter 2E Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Coxter 2E Tablet is a combination of three medicines: Rifampicin, isoniazid and ethambutol which treat tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce, while isoniazid prevents these bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.
Coxter 2E Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
WEIGH RISKS VS BENEFITS
Coxter 2E Tablet may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Coxter 2E Tablet is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Do not drive unless you are feeling well. Coxter 2E Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Coxter 2E Tablet should be used with caution in patients with kidney disease. Dose adjustment of Coxter 2E Tablet may be needed. Please consult your doctor. Kidney function tests are advisable before the start of this medicine.
Coxter 2E Tablet should be used with caution in patients with liver disease. Dose adjustment of Coxter 2E Tablet may be needed. Please consult your doctor.
Q. What is the most important information I should know about the Coxter 2e?
Take the proper course of medicine that has been prescribed for you even if you begin to feel better. Avoid alcohol while taking this medicine as it increases the risk of damage to your liver during treatment. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.
Q. Which is the best time to take Coxter 2e?
Take the Coxter 2e exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.
Q. Can the use of Coxter 2e makes birth control pills ineffective?
Yes, Coxter 2e can make birth control pills less effective. Ask the doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking Rifampicin+Isoniazid.
Q. Is tuberculosis a curable disease?
Yes, tuberculosis (TB) is a curable disease and usually with 6–9 months of treatment. Drug-resistant forms of TB are also curable, but more difficult to treat. Treatment for drug-resistant TB can last up to 2 years and require medications that can cause serious side-effects.
Q. Can I drive while I am taking the Coxter 2e?
No, Coxter 2e may cause visual disturbances that can impair your ability to drive and to use machines, as it has ethambutol in it.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 8th Mar 2017.