Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combitram D Tablet may be taken with or without food, but it is better to take it at a fixed time.
Combitram D Tablet is a combination of three medicines: domperidone, paracetamol and tramadol. Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. Paracetamol is an analgesic (pain reliever) and anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause fever and pain. Tramadol is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.
Taking Domperidone+Paracetamol / Acetaminophen+Tramadol with alcohol can cause liver damage.
WEIGH RISKS VS BENEFITS
Combitram D Tablet may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Combitram D Tablet is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby. Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Do not drive unless you are feeling well. Combitram D Tablet may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
Combitram D Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combitram D Tablet may be needed. Please consult your doctor.
Combitram D Tablet should be used with caution in patients with liver disease. Dose adjustment of Combitram D Tablet may be needed. Please consult your doctor.