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Combipara TR Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 01 Dec 2025 | 12:39 AM (IST)
Combipara TR Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.
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General Information

Contains

Aceclofenac (100mg)+ Paracetamol (325mg)+ Tramadol (37.5mg)

Marketer

Delcure Life Sciences

Storage

Store below 30°C
The content is shown in English
Combipara TR Tablet image
Combipara TR Tablet image

Product introduction

Combipara TR Tablet should be taken with or without food. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, diarrhea, stomach pain, loss of appetite, flatulence, and headache. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help you with ways to reduce or prevent the side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Combipara TR Tablet

Benefits of Combipara TR Tablet

Pain relief
Combipara TR Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondolytis. It also helps to manage short term symptoms such as muscle and back pain, toothache, or pain in the ear and throat if taken when the first sign of pain occurs. It works by reducing substances in the body that causes pain and swelling. Combipara TR Tablet also reduces fever associated with various painful conditions within 1-2 hour of taking a dose.

Side effects of Combipara TR Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Combipara TR
  • Nausea
  • Vomiting
  • Stomach pain
  • Indigestion
  • Loss of appetite
  • Dryness in mouth
  • Dizziness
  • Sleepiness
  • Heartburn

How to use Combipara TR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combipara TR Tablet may be taken with or without food.

How Combipara TR Tablet works

Combipara TR Tablet is a combination of three medicines: Aceclofenac, Paracetamol and Tramadol. Paracetamol is an analgesic (pain reliever) as well as an antipyretic (fever reducer). Aceclofenac is a non-steroidal antiinflammatory drug (NSAID). Together, both of them work by blocking the release of certain chemical messengers in the brain that cause pain. Tramadol is an opioid analgesic ( very strong pain reliever) which works by blocking transmission of pain signals to the brain to lower the pain perception.

Quick tips

  • Combipara TR Tablet is used to reduce pain and swelling in various conditions.
  • Take it with food to avoid getting an upset stomach.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
  • Inform your doctor if you have liver or kidney disease, as dose adjustment might be required.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Combipara TR Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Combipara TR Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Combipara TR Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Combipara TR Tablet may cause side effects that could affect your ability to drive.
Combipara TR Tablet may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
Kidney

Kidney

CAUTION
Combipara TR Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Combipara TR Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Combipara TR Tablet is used to relieve moderate to severe pain caused by conditions such as arthritis, muscle pain, injuries, post-surgical pain, etc.
Individuals should avoid taking Combipara TR Tablet if they have allergies to any of its components, active stomach ulcers or bleeding, severe liver or kidney disease, heart failure, epilepsy, or a history of asthma or allergic reactions to painkillers. It is also not recommended for pregnant or breastfeeding women without a doctor’s supervision.
Serious side effects of Combipara TR Tablet include allergic reactions, such as rash, swelling, difficulty breathing, severe stomach pain, black or bloody stools, or unusual bleeding. Seek medical help immediately if you notice these symptoms.
Combipara TR Tablet is usually prescribed for adults and children over 12 years under strict medical supervision. Elderly patients may be more sensitive to side effects, such as dizziness, and should be monitored closely.
Combipara TR Tablet is generally prescribed for short-term use, often not more than 5 days, to avoid risks of dependence and serious side effects. Always follow your doctor’s instructions on duration, and do not stop or change your dose without consulting your doctor.

Fact Box

Habit Forming

Yes

Therapeutic Class

PAIN ANALGESICS

References

  1. Wewege MA, Bagg MK, Jones MD, et al. Comparative effectiveness and safety of analgesic medicines for adults with acute non-specific low back pain: systematic review and network meta-analysis. BMJ. 2023 Mar 22;380:e072962. [Accessed 24 Nov. 2025]. Available from:
  2. Cao Z, Han K, Lu H, et al. Paracetamol Combination Therapy for Back Pain and Osteoarthritis: A Systematic Review and Meta-Analyses. Drugs. 2024 Aug;84(8):953-967. [Accessed 24 Nov. 2025]. Available from:
  3. Banerjee S, Butcher R. Pharmacological Interventions for Chronic Pain in Pediatric Patients: A Review of Guidelines [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2020 May 5. [Accessed 24 Nov. 2025]. Available from:
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User feedback

Twice A Day
67%
Once A Day
33%
Pain relief
100%
Excellent
100%
No Side Effect
100%
With food
100%
Not Expensive
67%
Average
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Delcure Life Sciences
Address: Kerom 3rd Floor Plot No A112, Near State Bank of India Road No 22, Wagle Industrial Estate Thane (W) Pin: 400604

Vendor Details

Country of origin: India

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