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Combipara-SP Tablet is a combination medicine that relieves muscle, joint, and postoperative pain. It relieves pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 09 Apr 2026 | 09:26 PM (IST)
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General Information

Contains

Aceclofenac (100mg)+ Paracetamol (325mg)+ Serratiopeptidase (15mg)

Marketer

Delcure Life Sciences

Storage

Store below 30°C
The content is shown in English
Combipara-SP Tablet image
Combipara-SP Tablet image
Combipara-SP Tablet image
Combipara-SP Tablet image
Combipara-SP Tablet image
Combipara-SP Tablet image
Combipara-SP Tablet image

Product introduction

Combipara-SP Tablet should be taken at the dose and duration advised by your doctor. It should be taken with food or milk to prevent stomach upset. Taking the medicine regularly at the correct times increases its effectiveness. It is important to continue taking it until your doctor tells you it is safe to stop.


Common side effects of Combipara-SP Tablet include nausea, vomiting, stomach pain, indigestion, heartburn, increased liver enzymes, dizziness, drowsiness, and diarrhea. Your doctor may regularly monitor your kidney function, liver function, and blood component levels if you take this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.


Take it as prescribed to get the most benefit. Do not take more or longer than needed, as that can be dangerous. In general, you should take the lowest dose that works for the shortest possible time. This will help you go about your daily activities more efficiently and have a better, more active quality of life. Combipara-SP Tablet is not recommended if you are pregnant or breastfeeding.

Uses of Combipara-SP Tablet

  • Pain relief : Combipara-SP Tablet helps relieve acute pain in conditions such as muscle injuries, joint pain, dental pain, or pain after surgery.

Benefits of Combipara-SP Tablet

Pain relief
Pain and inflammation can occur due to injury or conditions affecting the joints and muscles. Combipara-SP Tablet helps reduce pain, inflammation, and swelling while supporting the healing process. This relieves discomfort in conditions such as arthritis, muscle pain, and post-injury swelling. It improves movement and supports faster recovery.

Side effects of Combipara-SP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Combipara-SP
  • Vomiting
  • Stomach pain
  • Indigestion
  • Heartburn
  • Loss of appetite
  • Diarrhea
  • Dizziness
  • Increased liver enzymes
  • Drowsiness
  • Nausea

How to use Combipara-SP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combipara-SP Tablet should be taken with or after food.

How Combipara-SP Tablet works

Combipara-SP Tablet is a combination of three medicines: Aceclofenac, Paracetamol, and Serratiopeptidase. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the body that cause pain and fever. Serratiopeptidase is an enzyme that works by breaking down abnormal proteins at the site of inflammation and helps support healing.

All substitutes for Combipara-SP Tablet

For information purposes only. Consult a doctor before taking any medicine.

Alcinac Forte 100mg/325mg/15mg Tablet

by Leeford Healthcare Ltd
₹4.88/tablet
45% cheaper
<h3 class=bodySemiBold>Alcinac Forte 100mg/325mg/15mg Tablet</h3>

Acimol-Forte Tablet

by Leeford Healthcare Ltd
₹6.13/tablet
31% cheaper
<h3 class=bodySemiBold>Acimol-Forte Tablet</h3>

Movexx SP Tablet

by Cipla Ltd
₹7.35/tablet
17% cheaper
<h3 class=bodySemiBold>Movexx SP Tablet</h3>

Nicip ASP 100mg/325mg/15mg Tablet

by Cipla Ltd
₹7.35/tablet
17% cheaper
<h3 class=bodySemiBold>Nicip ASP 100mg/325mg/15mg Tablet</h3>

acemiz-S Tablet

by Lupin Ltd
₹8.83/tablet
same price
<h3 class=bodySemiBold>acemiz-S Tablet</h3>

Quick tips

  • Take Combipara-SP Tablet after food to reduce stomach irritation.
  • Do not take Combipara-SP Tablet with other medicines containing paracetamol (acetaminophen), such as some cold or fever medicines, unless advised by your doctor.
  • Avoid combining Combipara-SP Tablet with other NSAID painkillers unless your doctor recommends it.
  • Avoid alcohol while taking Combipara-SP Tablet, as it may increase stomach irritation and the risk of liver damage.
  • Combipara-SP Tablet may cause dizziness or drowsiness, so avoid driving or operating machinery until you know how it affects you.
  • Stay well hydrated while using Combipara-SP Tablet, as dehydration may increase the risk of kidney-related side effects.
  • Inform your doctor if you have kidney disease, heart disease, asthma, stomach ulcers, or uncontrolled high blood pressure before taking Combipara-SP Tablet.
  • Seek urgent medical attention if you notice black stools, vomiting blood, severe stomach pain, or unusual bruising.
  • Stop taking Combipara-SP Tablet and seek medical help if you develop rash, swelling of the face, or breathing difficulty.
  • Use Combipara-SP Tablet only for the duration prescribed, and consult your doctor if pain, swelling, or fever persists despite treatment.
  • Tell your doctor if you are taking blood thinners, steroids, or certain antidepressants that may increase bleeding risk.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Combipara-SP Tablet
Pregnancy

Pregnancy

UNSAFE
Combipara-SP Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Combipara-SP Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Combipara-SP Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

UNSAFE
Combipara-SP Tablet is unsafe to use in patients with kidney disease and should be avoided.
Use of Combipara-SP Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Combipara-SP Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Combipara-SP Tablet is not recommended in patients with severe liver disease and active liver disease.

Frequently asked questions

Combipara-SP Tablet is used to relieve pain, swelling, and inflammation in conditions such as muscle injuries, joint pain, dental pain, or after surgery. It contains medicines that work together to reduce pain signals, lower inflammation, and decrease swelling, helping improve comfort and recovery when used as prescribed by a doctor.
Combipara-SP Tablet should be taken only in the dose and frequency advised by your doctor. The correct dosing depends on the ingredients in Combipara-SP Tablet, the severity of your pain, and your overall health. Taking it more often than prescribed may increase the risk of stomach irritation, acidity, or other side effects.
Combipara-SP Tablet is usually used for short-term pain relief and may be stopped once the pain improves. However, if your doctor has advised you to continue it for a specific duration, follow their instructions and do not stop it earlier without medical advice.
Combipara-SP Tablet may cause side effects such as stomach upset, nausea, vomiting, heartburn, dizziness, loose stools, or mild drowsiness in some people. These effects are usually mild and temporary. Taking it with food and staying well hydrated may help reduce stomach discomfort. Stop the medicine and seek medical help if you develop severe rash, breathing difficulty, black stools, or yellowing of the skin or eyes.
Yes, Combipara-SP Tablet can generally be taken with vitamin B-complex supplements if advised by your doctor. While Combipara-SP Tablet helps relieve pain and inflammation, vitamin B-complex may support nerve health and help correct certain vitamin deficiencies.
Combipara-SP Tablet should be avoided or used only under medical advice in people with allergy to painkillers, a history of stomach ulcers or bleeding, severe liver or kidney disease, uncontrolled high blood pressure, or heart failure. It is also generally not recommended during pregnancy, especially in the later stages.
If you miss a dose of Combipara-SP Tablet, take the next scheduled dose at the usual time unless your doctor advises otherwise. Do not take two doses together to make up for a missed dose because this may increase the risk of side effects.
Combipara-SP Tablet is often easier on the stomach when taken after food. Taking it on an empty stomach may increase the chance of stomach irritation or acidity. Follow your doctor’s advice regarding the exact timing.
It is generally best to avoid alcohol while using Combipara-SP Tablet because alcohol may increase the risk of stomach irritation, drowsiness, dehydration, or liver stress.
The duration of relief from Combipara-SP Tablet can vary depending on the ingredients, the type of pain being treated, and individual response. It should always be used only for the duration advised by your doctor.
Combipara-SP Tablet may help relieve certain types of pain associated with inflammation or tissue injury. However, nerve pain can have different causes, and the suitability of Combipara-SP Tablet depends on your specific condition. Always consult your doctor for appropriate treatment.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 19 Apr. 2019] (online) Available from:
  2. Taj Life Sciences. Aceclofenac, Paracetamol and Serratiopeptidase [Product Information]. [Accessed 12th Sept. 2023] (online) Available from:
  3. Aceclofenac, Paracetamol & Serratiopeptidase [Prescribing Information]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Pvt. Ltd.; 2021. [Accessed 24 Mar. 2026] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Delcure Life Sciences
Address: Kerom 3rd Floor Plot No A112, Near State Bank of India Road No 22, Wagle Industrial Estate Thane (W) Pin: 400604

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Combipara-SP Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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