Combidin 325 mg/30 mg/400 mg Tablet

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Somatico Laboratories Pvt Ltd

Composition for Combidin 325 mg/30 mg/400 mg Tablet

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Primarily used for

Fever, Moderate to severe pain, Headache
Potentiallyunsafewith
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Alcohol
NOT FOR SALE
We do not sell this product at present

Medicine Overview of Combidin 325 mg/30 mg/400 mg Tablet

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Uses of Paracetamol

Paracetamol is used in fever, headache, pain during menstruation, arthralgia, myalgia, dental pain and post operative pain.
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Side effects of Paracetamol

Common

Allergic reaction.

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How to use Paracetamol

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

How Combidin 325 mg/30 mg/400 mg Tablet works

Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that is responsible for pain and fever.
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Uses of Codeine

Codeine is used for moderate to severe pain and dry cough.
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Side effects of Codeine

Common

Sweating, Headache, Dizziness, Sleepiness, Vomiting, Weakness, Dehydration, Lightheadedness, Nausea, Edema, Dry mouth, Fatigue, Anemia, Sedation, Constipation.

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How to use Codeine

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

How Combidin 325 mg/30 mg/400 mg Tablet works

Codeine is an opioid analgesic ( pain reliever). It works by decreasing the perception of pain by blocking the transmission of pain signals to the brain.
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Uses of Ibuprofen

Ibuprofen is used in fever, headache, arthralgia, myalgia, dental pain, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.
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Side effects of Ibuprofen

Common

Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.

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How to use Ibuprofen

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

How Combidin 325 mg/30 mg/400 mg Tablet works

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

In Depth Information on Combidin 325 mg/30 mg/400 mg Tablet

Expert advice for Paracetamol

  • Paracetamol is a very safe and well-tolerated medicine for short term use.
  • Taking high dose of Paracetamol can cause serious liver damage.
  • Inform your doctor if you have a liver disease. Your dose may need to be adjusted.
  • Avoid excess intake of alcohol when taking Paracetamol, together they can affect your liver.
  • Immediately inform your doctor or contact a hospital emergency if you have taken an overdose of Paracetamol and you are feeling unwell.

Expert advice for Codeine

  • Use Codeine as instructed by your doctor. Never take in greater amounts or more often than prescribed.
  • It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
  • Avoid consuming alcohol when taking the Codeine, as it may cause excessive sleepiness or drowsiness.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • Store opioid pain relievers in a safe place and out of reach of others.

Expert advice for Ibuprofen

  • It should be taken with food or milk to avoid getting an upset stomach.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • Ibuprofen can raise your risk of blood clots, heart attack, or a stroke.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Warnings
Special precautions for Combidin 325 mg/30 mg/400 mg Tablet
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Alcohol
CAUTION
Combidin 325 mg/30 mg/400 mg Tablet may cause excessive drowsiness and calmness with alcohol.

Taking Paracetamol with alcohol can cause liver damage.
Taking Ibuprofen with alcohol increases the risk of stomach bleeding.
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Pregnancy
WEIGH RISKS VS BENEFITS
Combidin 325 mg/30 mg/400 mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
SAFE
Combidin 325 mg/30 mg/400 mg Tablet is safe to use during la
ctation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
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Driving
Do not drive unless you are feeling well.

As Combidin 325 mg/30 mg/400 mg Tablet may cause dizziness, blurred vision or the inability to think clearly.
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Kidney
CAUTION
Combidin 325 mg/30 mg/400 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combidin 325 mg/30 mg/400 mg Tablet may be needed. Please consult your doctor.

Use of Combidin 325 mg/30 mg/400 mg Tablet is not recommended in patients with severe kidney disease. Long term use of this medicine can affect the kidney function.
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Liver
CAUTION
Combidin 325 mg/30 mg/400 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combidin 325 mg/30 mg/400 mg Tablet may be needed. Please consult your doctor.

However, the use of Combidin 325 mg/30 mg/400 mg Tablet is not recommended in patients with severe liver disease and active liver disease.
Use of Combidin 325 mg/30 mg/400 mg Tablet is not recommended in patients with severe liver disease.
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Patient Concerns

Frequently asked questions for Combidin 325 mg/30 mg/400 mg Tablet

Frequently asked questions for Paracetamol

Q. Can I take Paracetamol with vitamin B complex?
Yes, Paracetamol can be taken with vitamin B-complex preparations. They have been used together in the treatment of acute and painful diseases affecting nerves like trigeminal neuralgias, post-operative pain, etc. Paracetamol helps to relieve pain and vitamin B-complex corrects the deficiency that might be causing your symptoms.
Q. Is Paracetamol use associated with Helicobacter pylori infection?
No, Paracetamol use is not associated with Helicobacter pylori infection. Painkiller drugs can increase the acid secretion in the stomach, aggravate the symptoms of this infection and the risk of stomach and the intestine ulcer. However, this risk is minimum with Paracetamol as compared to other pain killers.
Q. Can I take Paracetamol with fexofenadine?
Yes, Paracetamol can be taken safely with fexofenadine. No drug-drug interactions or any harmful effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore-throat and other allergic or viral diseases. Fexofenadine helps to relieve sneezing, runny nose, itchy throat, or eyes and Paracetamol helps to relieve pain or fever.
Q. Can I take Paracetamol with warfarin?
Paracetamol is safe to use occasionally with warfarin as other painkillers like ibuprofen and aspirin can increase the risk of bleeding. However, on a long-term use, Paracetamol can also increase the risk of bleeding. Talk to your doctor before taking them together as you may need to be monitored regularly.
Q. Can I take Paracetamol with tamsulosin?
Paracetamol can be taken with Tamsulosin. No harmful side effects or other interactions have been seen when they are taken together. Tamsulosin is an alpha adrenergic receptor blocker used to treat symptoms of benign prostatic hyperplasia.
Q. Can I take Paracetamol with cetirizine?
Yes, Paracetamol can be taken safely with cetirizine. No drug-drug interactions or any harmful effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore throat and other allergic or viral diseases. Cetirizine helps to relieve sneezing, runny nose, itchy throat, or eyes and Paracetamol helps to relieve pain or fever.
Q. Can I take Paracetamol with ibuprofen?
Yes, Paracetamol can be taken with ibuprofen. Both help to relieve pain and fever and ibuprofen also decreases inflammation and swelling. However, both increase the acid secretion in the stomach and can cause acid reflux, heartburn, stomach, and intestinal ulcers and gut bleeding on long-term use.
Q. Does Paracetamol cause weight loss?
Paracetamol is not known to cause weight loss. It is a very safe medicine for short term use and can cause minor and rare side effects like low blood pressure, and allergic reactions.
Q. Can anyone be allergic to Paracetamol?
Yes, there have been reports of hypersensitivity and allergic reaction with the use of Paracetamol. Symptoms of an allergy include swelling of the face, mouth, and throat, shortness of breath, urticaria, red rash, and severe itching. Stop taking Paracetamol if you have such symptoms and immediately consult your doctor.
Q. How beneficial is to use Paracetamol with diclofenac?
Paracetamol and Diclofenac might be given together in case of fever and pain. Paracetamol has an early onset of action and it helps in relieving the symptoms till diclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.
Q. Can I take Paracetamol for stomach pain?
No, Paracetamol should not be taken for stomach pain. You must consult your physician for this. The stomach pain could be due to some underlying condition, which needs attention.
Q. Can I take Paracetamol with aceclofenac?
Yes, Paracetamol can be given with aceclofenac for fever and pain. Paracetamol has an early onset of action and it helps in relieving the symptoms till Aceclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.
Q. Does Paracetamol treat sore-throat, flu or cold?
Paracetamol does not treat sore-throat, flu or cold but it can help in relieving fever and body aches associated with these conditions.
Q. Can I take Paracetamol with codeine?
Paracetamol and codeine can be taken together. No drug-drug interactions or any harmful effects have been reported when they are used together. They are commonly given together for the relief of mild to moderate pain due to different reasons.
Q. Does Paracetamol help a cough?
No, Paracetamol does not help in the relief of cough but it can help in relieving associated fever and body aches.
Q. Does Paracetamol contain alcohol?
No, Paracetamol does not contain any alcohol.
Q. Can I take Paracetamol with amoxicillin?
Paracetamol and amoxicillin can be taken together. Amoxicillin is an antibiotic and is used to treat bacterial infections. Paracetamol is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Does Paracetamol have side effects?
Paracetamol is quite safe for short term use. It has side effects if taken in more than the dose advised and for a long-term. Immediately consult a doctor if there is nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice as it could be due to an overdose of Paracetamol.
Q. Is Paracetamol safe to use?
Paracetamol is safe to use in the dose as advised by the doctor. Use in more than recommended doses can do serious harm.
Q. Is it safe to take Paracetamol with erythromycin?
Paracetamol and Erythromycin can be taken together. Erythromycin is an antibiotic and is used to treat bacterial infections. Paracetamol is given along, for the relief of associated fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is Paracetamol an antibiotic?
Paracetamol is not an antibiotic. It's an analgesic (pain-killer) and antipyretic (for the relief of fever), whereas an antibiotic is useful for the treatment of infections.
Q. Can I take Paracetamol with metronidazole?
Paracetamol and Metronidazole can be taken together. No drug-drug interactions or any harmful effects have been reported when used together.
Q. Can I take Paracetamol with homeopathic medicine?
Ask your doctor before taking Paracetamol with homeopathic medicine as there is no information available on this.
Q. Is it safe to take Paracetamol with Tramadol?
Yes, Paracetamol can be taken with Tramadol. They are used together for moderate to severe pain in various diseases and their use is associated with common side effects like nausea, dizziness, and sleepiness.No drug-drug interactions have been reported when they are used together.
Q. Can I take Paracetamol with Azithromycin?
Paracetamol and Azithromycin can be taken together. Azithromycin is an antibiotic and is used to treat bacterial infections. Paracetamol is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is it safe to take Paracetamol with Naproxen?
Yes, Paracetamol can be taken with Naproxen. Both are painkillers and belong to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and are used to relieve pain and fever. However, long-term use affects the stomach lining and increase acid secretion which can lead to side effects like acid reflux, heartburn, stomach, and intestinal ulcers and bleeding.
Q. Can a patient with high blood pressure take Paracetamol?
Occasional use of Paracetamol is safe in patients with high blood pressure. However, if it is to be taken for a long time, you must talk to your doctor. Paracetamol belongs to the group of painkillers called analgesics and antipyretics and these drugs can decrease the action of medicines taken by the patient for control of high blood pressure.
Q. Does Paracetamol interact with vitamin C?
Vitamin C can be taken with Paracetamol. However, vitamin C increases the blood levels of other drugs similar to Paracetamol, so it is advised to talk to your doctor if you have to take both these medicines for a long-term.
Q. What happens if you take an overdose of Paracetamol?
Overdose of Paracetamol can cause potentially life-threatening liver damage, which is the most serious side effect. Early symptoms may include nausea, vomiting, profuse sweating, and general tiredness. Kidney damage, decreased platelet count and coma may also occur. Immediately consult a doctor or consult an emergency in the case of suspected overdosage.
Q. What is the difference between Paracetamol and Ibuprofen?
Both Paracetamol and ibuprofen help to relieve mild to moderate pain and fever. Ibuprofen also helps to decrease redness and swelling because of the anti-inflammatory action while Paracetamol has no anti-inflammatory action. But the use of Paracetamol is much safer as it causes fewer side effects like stomach upset, ulcers, and bleeding than Ibuprofen.
Q. Can I take Paracetamol with hyoscine?
Yes, Paracetamol and hyoscine can be taken together. Hyoscine is used to relieve pain and cramps of the stomach, gut, urinary bladder and urinary tract while Paracetamol is used to relieve mild to moderate pain of a headache, toothache, muscle pain, joint pain, and fever. Together they can be advised by a doctor for painful conditions of the gut and urinary tract.
Q. Can I take Paracetamol with Betahistine?
Paracetamol can be taken with Betahistine. There are no reported drug-drug interactions or harmful effects when they are used together.
Q. Can I take Paracetamol with rabeprazole?
Paracetamol and Rabeprazole can be taken together. Rabeprazole is used to prevent Paracetamol (painkillers) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no clinically significant drug-drug interactions or harmful effects seen when they are used together.
Q. How is aspirin different from Paracetamol?
Paracetamol helps to relieve mild to moderate pain and fever and has no effect on inflammation or swelling while Aspirin acts as a blood thinner in low doses and is helpful to prevent heart attacks and stroke and in higher doses, it relieves mild to moderate pain, fever, and inflammation.
Q. How beneficial is to take urofollitropin alpha with Paracetamol?
Urofollitropin alpha is given as a subcutaneous injection with the human chorionic gonadotropin (hCG) hormone to assist in ovulation and fertility. Urofollitropin alpha can cause abdominal or pelvic pain or pain and swelling at the injection site in some patients which can be relieved by taking Paracetamol.
Q. Can vitamin D be taken safely with Paracetamol?
Yes, vitamin D can be taken with Paracetamol. Patients with osteoarthritis who are on vitamin D and calcium may need to take Paracetamol for the relief of any associated pain. No drug-drug interactions or any harmful effects have been reported.
Q. Can I take clindamycin with Paracetamol?
Paracetamol and Clindamycin can be taken together. Clindamycin is an antibiotic and is used to treat bacterial infections. Paracetamol may be given along, for the relief of associated fever. No drug-drug interactions have been reported clinically. However, both are known to cause liver damage. Talk to your doctor if you need them for a long time.
Q. Does Paracetamol affect the liver?
Use of Paracetamol for a long time and above recommended doses can cause liver damage ranging from abnormal liver tests to liver failure. If you are taking Paracetamol from a long time and have nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice, inform your doctor as these could be signs of an underlying liver damage.
Q. Can I take Paracetamol if I have hepatitis?
Paracetamol is considered the safest painkiller to take for people with hepatitis for mild to moderate pain and fever. However, Paracetamol is metabolized in the liver, so, consult your doctor before taking Paracetamol if you have hepatitis as it can cause liver damage if taken in higher doses or for a very long time.
Q. What are the serious side effects of taking excess Paracetamol?
Potentially severe life-threatening liver injury is a serious side effect seen with an overdose of Paracetamol. Overdose can also cause kidney injury, coma, and decreased platelet count. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of suspected overdose.
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Frequently asked questions for Codeine

Q. Is Codeine legal in India?
Yes, however Codeine containing tablets require prescription in India
Q. Is Codeine addictive?
Codeine may cause addiction when consumed for longer duration. Patients should follow the advice of the doctor regarding its use
Q. Is Codeine a narcotic/hydrocodone/morphine/depressant?
Codeine is a naturally occurring form of morphine and called as narcotic. Hydrocodone is derived form of Codeine. Codeine is not a depressant drug
Q. Is Codeine strong?
It depends on the dose. Patients should follow the advice of the doctor regarding its use
Q. Is Codeine/Corex/Phensedyl over the counter or banned in India?
No, it is available in India with doctor's prescription only
Q. Is Codeine/Corex bad or harmful?
It is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Corex a drug?
No, Corex is a cough syrup which contains codeine as one of its component
Q. What is Paracodin/Paracodin tablets/Paracodin 10 mg/Paracodol/Paracodina/Paracodin drops/Phensedyl/Phensedyl cough syrup used for?
These are the trade names of codeine containing products. Your doctor may prescribe it (depending on the disease condition) for the treatment of mild to moderate pain, diarrhea, cough, irritable bowel syndrome
Q. Can I take Codeine for flu/headache/toothache/cold/back pain/tonsillitis/migraine/menstrual cramps/stomach pain?
Codeine is specifically used for the treatment of mild to moderate pain, diarrhea, cough, irritable bowel syndrome. Patients should follow the advice of the doctor regarding its use
Q. Can I take codeine with naproxen/paracetamol/ibuprofen/advil/ warfarin/metronidazole/hydrocodone/diclofenac/ amoxicillin?
You can take codeine with paracetamol/ibuprofen/ Advil/ warfarin/ diclofenac/amoxicillin/naproxen. Taking metronidazole and hydrocodone may alter the effects of codeine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required
Q. Does Codeine expire?
Codeine containing tablets are available with mention of expiry date on it. Before taking medicine, patient should consult pharmacist or doctor
Q. Does Codeine make you high/tired/fat/awake/ sleep/constipate/thin blood/headache?
Codeine causing these side effects is rare or uncommon. However, consult your doctor if you experience any of these side effects
Q. Does Codeine have acetaminophen in it?
No, it does not contain acetaminophen in it. However, your doctor may prescribe Codeine along with acetaminophen.
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Frequently asked questions for Ibuprofen

Q. Is Ibuprofen safe?
Ibuprofen is safe if used at the doses and for the duration prescribed by the doctor. Patients should follow the advice of the doctor regarding its use.
Q. Can I take Ibuprofen with Betahistine?
Ibuprofen can be taken with Betahistine. There are no reported drug interactions or harmful effects when they are used together.
Q. Can I take Ibuprofen with Tamsulosin or paracetamol?
Ibuprofen can be taken with Tamsulosin or paracetamol. No harmful side effects or other interactions have been seen when they are taken together.
Q. Can I take Ibuprofen with rabeprazole?
Ibuprofen can be taken with Rabeprazole . Rabeprazole is used to prevent painkiller (NSAIDs) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no reported drug interactions or harmful effects when they are used together.
Q. Can I take Ibuprofen with famotidine?
Ibuprofen can be taken with Famotidine as no harmul effects have been seen when they are used together. Ibuprofen is a pain killer and belongs to the group of NSAIDs (non-steroidal anti-inflammatory agents) and you should be careful while taking NSAIDs as they are strong gastric acid stimulators and would increase the gastric acid secretion and further worsen your underlying condition.
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