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06 Jun 2019 | 02:49 PM (IST)
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Colospa X Tablet



Colospa X Tablet is a combination of two medicines that is effective in treating irritable bowel syndrome (IBS). The medicine works by relaxing the stomach muscles to reduce pain, cramps and other symptoms of IBS.

Colospa X Tablet should be taken by mouth in the dose and duration advised by your doctor. Taking this medicine before meals enhances its absorption in the body. It is better not to take more than the recommended doses of this medicine, as high dose may have harmful effects on the body. Long-term intake of this medicine may lead to withdrawal symptoms.

This medicine is generally well tolerated by patients. However, a few side effects such as dryness in mouth, constipation, sleepiness, dizziness, and fatigue may be experienced. Proper hydration helps to overcome these side effects. Before taking the medicine, always consult your doctor if you are pregnant or breastfeeding. Also let your doctor know if you are suffering from any severe stomach, liver or kidney disease, or any other known disease. You may feel sleepy or dizzy, so it is recommended not to drive while you are on this medicine.

Uses of Colospa X Tablet

Colospa X Tablet side effects

  • Sleepiness
  • Drowsiness
  • Fatigue
  • Confusion
  • Uncoordinated body movement
  • Abnormality of voluntary movements
  • Skin rash
  • Slurred speech

How to use Colospa X Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Colospa X Tablet is to be taken empty stomach.
Take it preferably 20 minutes before food.

How Colospa X Tablet works

Colospa X Tablet is a combination of two medicines: Mebeverine and Chlordiazepoxide. Mebeverine is an antispasmodic medicine which relaxes the muscles of the intestine and relieves spasm. Chlordiazepoxide is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Colospa X Tablet related warnings

It is unsafe to consume alcohol with Colospa X Tablet
Colospa X Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Information regarding the use of Colospa X Tablet during lactation is not available. Please consult your doctor.
Colospa X Tablet may cause side effects which could affect your ability to drive.
As Colospa X Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Colospa X Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Colospa X Tablet may not be needed in these patients. Please consult your doctor.
Caution is advised in patients with severe kidney disease.
Colospa X Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Colospa X Tablet may not be needed in these patients. Please consult your doctor.
Caution is advised in patients with severe liver disease.

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For informational purposes only. Consult a doctor before taking any medicines.
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Patient Concerns

Questions Related to Colospa X

I've been suffering from Irritable Bowel Syndrome for 4 years. Morning one episode of watery diarrhea after breakfast. I consulted a doctor and he gave me Ramosetron Hydrochloride 5mcg and advised to use half of the Tablet at night before food and I got temporary cure. But after when I stop the Tablet the problem is recurring so I request you to suggest some better remedy for this condition. And can continue with the same Tab I used?. Is it good for a long term use?. Is there any severe side effect with the Tab? Thanking You, PATIENT
Dr. Kunal Parasar
Treatment of ibs cant b done on such online platform. It needs a individualized treatment. Consult a gastroenterologist near u
Suffering from irritable bowel syndrome. Belly pain and then looser stools than normal. I am taking drugs of diabetes and hypertension. I have attached medical reports and doctor prescription. Thanks.
Dr. Aanchal Maheshwari
Start Tablet Stop Ibs( charak ) 2 tab twice for 21 days, along with above medicine, Avoid heavy , spicy and junk food.
Do you have any questions related to Colospa X Tablet?

User Feedback


Q. Can Colospa X cause withdrawal symptoms?

Yes, Colospa X may cause withdrawal symptoms. Do not stop taking Colospa X all of a sudden. Stopping Colospa X suddenly can cause seizures, shaking, stomach and muscle cramps, vomiting and sweating. Consult with your doctor before stopping Colospa X.

Q. Can I drink alcohol while taking Colospa X?

No, avoid drinking alcohol while you are taking Colospa X. Drinking alcohol can increase the risk of side effects like drowsiness or sleepiness.

Q. Can the use of Colospa X cause sleepiness or drowsiness?

Yes, Colospa X may make you feel drowsy or sleepy. Avoid driving, operating any machines, working at heights or participating in potentially dangerous activities at the start of your treatment. Inform your doctor if you experience such episodes while taking this medicine.

Q. What precautions do I need to take while using Colospa X?

Colospa X should not be taken along with opioid-like substances as it contains chlordiazepoxide. Use of opioids along with chlordiazepoxide may cause excessive sedation (state of calm or sleep), respiratory depression and eventually coma or death. Inform your doctor about all the medicines that you are taking if you are advised to take Colospa X.

Q. What are the instructions for storage and disposal of Colospa X?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What are the symptoms of overdose of Colospa X?

Both Mebeverine and Chlordiazepoxide show different symptoms of overdose. Chlordiazepoxide can cause sleepiness, reflexes, confusion and coma. Whereas, Mebeverine can cause CNS excitability which is mild and reversible. Inform the doctor in case you take a higher dose and any of these symptoms appear.

Q. Can the use of Colospa X cause constipation?

Yes, the use of Colospa X can cause constipation. Eat high-fiber foods like vegetables, fruits and cereals, and drink plenty of water. Exercise regularly by engaging in activities like swimming, jogging or taking a walk. Consult a doctor if the constipation persists for a long duration.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Mebeverine hydrochloride. Châtillon-sur-Chalaronne, France: Mylan Laboratories SAS; 2016. [Accessed 28 Mar. 2019] (online) Available from:External Link
  2. Chlordiazepoxide Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:External Link
  3. Mebeverine hydrochloride. Potters Bar, Hertfordshire: Mylan Products Ltd.; 2005 [revised 26 Aug. 2016]. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Chlordiazepoxide hydrochloride. Ashford, Kent: Kent Pharmaceuticals Ltd.; 2003 [revised 16 Aug. 2018]. (online) Available from:External Link
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16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
We do not facilitate sale of this product at present


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