Cofleaf LS Syrup
Prescription Required
View available alternative with same salt composition
Product introduction
Cofleaf LS Syrup is a combination medicine used in the treatment of cough with mucus. It thins mucus in the nose, windpipe, and lungs, making it easier to cough out. It also provides relief from a runny nose, sneezing, itching, and watery eyes.
Cofleaf LS Syrup can be taken with or without food. Take it in the dose and duration advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back. Let your doctor know about all other medications you are taking, as some may affect, or be affected by, this medicine.
The most common side effects include nausea, diarrhea, stomach pain, vomiting, muscle cramps, headache, skin rash, and increased heart rate. Most of these effects are usually temporary and often resolve with time. Contact your doctor if you are concerned about any of these side effects. This medicine may also cause sleepiness, so do not drive or perform activities that require mental alertness until you know how this medicine affects you.
Never support self-medication or recommend your medicine to another person. Drink plenty of fluids while taking Cofleaf LS Syrup. Before taking this medicine, tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Avoid drinking alcohol while taking this medicine, as it can make sleepiness worse.
Uses of Cofleaf LS Syrup
Benefits of Cofleaf LS Syrup
In Treatment of Cough with mucus
A cough with mucus occurs when thick secretions block the airways, causing breathing difficulty and frequent coughing. Cofleaf LS Syrup loosens mucus, promotes its removal, and opens the airways. This helps reduce cough, clear congestion, and make breathing easier.
Side effects of Cofleaf LS Syrup
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cofleaf LS
- Nausea
- Vomiting
- Diarrhea
- Upset stomach
- Stomach pain
- Allergic reaction
- Dizziness
- Hives
- Tremors
- Palpitations
- Muscle cramp
- Increased heart rate
- Headache
- Rash
How to use Cofleaf LS Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Cofleaf LS Syrup may be taken with or without food.
How Cofleaf LS Syrup works
Cofleaf LS Syrup is a combination of three medicines: ambroxol, levosalbutamol, and guaifenesin. Ambroxol is a mucolytic that thins and loosens mucus in the airways, making it easier to cough up. Levosalbutamol is a bronchodilator that relaxes the muscles around the airways, helping open them and making breathing easier. Guaifenesin is an expectorant that helps clear mucus from the airways by making it thinner and less sticky, promoting its removal through coughing. Together, these medicines help reduce mucus buildup, ease breathing, and relieve cough associated with mucus.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Cofleaf LS Syrup
Pregnancy
CONSULT YOUR DOCTOR
The safety of Cofleaf LS Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Cofleaf LS Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Cofleaf LS Syrup may cause side effects that could affect your ability to drive.
Kidney
CAUTION
Cofleaf LS Syrup should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Cofleaf LS Syrup should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
What if you forget to take Cofleaf LS Syrup?
If you miss a dose of Cofleaf LS Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Cofleaf LS Syrup
₹72/Syrup
Alkof LS Plus Cough Syrup
Alkem Laboratories Ltd
₹129.35/syrup
62% costlier
Kofcatch LS Plus Syrup
KLM Laboratories Pvt Ltd
₹98.44/syrup
24% costlier
Ingahist LS Syrup
Inga Laboratories Pvt Ltd
₹60.94/syrup
24% cheaper
Borkuf L Syrup
Cadwell Pharma Private Limited
₹73.13/syrup
8% cheaper
Ericuf LS Syrup
Erika Remedies
₹56.25/syrup
29% cheaper
Quick tips
- Cofleaf LS Syrup is used to relieve cough with mucus by thinning and clearing phlegm from the airways.
- Drink plenty of fluids while taking Cofleaf LS Syrup, as this helps loosen mucus and improves its effect.
- Cofleaf LS Syrup is not meant for dry cough (cough without mucus).
- Cofleaf LS Syrup may cause dizziness or sleepiness. Do not drive or operate machinery until you know how it affects you.
- Stop taking Cofleaf LS Syrup and contact your doctor if you develop severe palpitations, chest discomfort, tremors, or a very fast heartbeat.
- Inform your doctor if you have heart disease, high blood pressure, thyroid disorders, or diabetes before taking Cofleaf LS Syrup.
- Do not take more than the recommended dose, as overdose may cause rapid heartbeat, nervousness, or tremors.
- Consult your doctor if your cough lasts more than a few days, worsens, or is accompanied by fever, breathlessness, or chest pain.
- Do not use Cofleaf LS Syrup without medical advice in children, pregnant or breastfeeding women.
Fact Box
Habit Forming
No
Therapeutic Class
RESPIRATORY
FAQs
What is Cofleaf LS Syrup and what is it used for?
Cofleaf LS Syrup is used to treat cough with mucus (wet or productive cough). It helps thin and loosen phlegm so it can be coughed out more easily and also relaxes the airway muscles to improve breathing. It contains ambroxol, a mucolytic that thins mucus; guaifenesin, an expectorant that reduces mucus stickiness; and levosalbutamol, a bronchodilator that relaxes airway muscles. Because it works by clearing mucus, it is usually not recommended for dry cough where little or no phlegm is present. Use it only as advised by a doctor.
What side effects can Cofleaf LS Syrup cause?
Cofleaf LS Syrup is generally safe when used as prescribed, but some people may experience nausea, vomiting, diarrhea, stomach pain, dizziness, headache, tremors, palpitations, or muscle cramps. Mild rash or allergic reactions may also occur. These effects are usually temporary. Stop the medicine and contact your doctor if you develop severe rash, breathing difficulty, fainting, a very fast heartbeat, or persistent vomiting or diarrhea.
Who should avoid Cofleaf LS Syrup or use it with caution?
Cofleaf LS Syrup should not be used by people who are allergic to any of its components. Cofleaf LS Syrup may interact with medicines such as beta-blockers and other drugs used for heart or breathing conditions. Extra care is needed during pregnancy, breastfeeding, or in people with kidney, liver, heart, or blood pressure problems. Always inform your doctor about your medical history and other medicines before using it.
When should Cofleaf LS Syrup be taken or used?
Cofleaf LS Syrup should be used only for the reason and duration advised by your doctor. Take it at the time recommended by your doctor. If it causes stomach discomfort, your doctor may suggest taking it after food and maintaining adequate hydration.
Can Cofleaf LS Syrup be taken with food or after meals?
Cofleaf LS Syrup should be taken exactly as advised by your doctor. Some people may prefer taking it after meals to reduce stomach discomfort. Food may affect comfort or how quickly the medicine works in some cases. If you are unsure about the timing with meals, consult your doctor for guidance.
Can I drink alcohol while using Cofleaf LS Syrup?
It is usually better to avoid alcohol while using Cofleaf LS Syrup unless your doctor advises otherwise. Alcohol may worsen side effects such as dizziness, stomach upset, vomiting, or dehydration. If you experience these side effects or unusual symptoms after mixing alcohol with this medicine, seek medical advice.
Can Cofleaf LS Syrup interact with other medicines?
Yes, Cofleaf LS Syrup can interact with some medicines. Taking it with other medicines without medical advice may increase the risk of side effects or make the treatment less effective. Always tell your doctor about all the medicines you are taking, including over-the-counter medicines and supplements.
Does Cofleaf LS Syrup contain paracetamol?
No, Cofleaf LS Syrup does not contain paracetamol; it contains ambroxol, guaifenesin, and levosalbutamol. These medicines help loosen and thin mucus, make it easier to cough out, and relax the airways to make breathing easier.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- European Medicines Agency. Revised assessment report: Ambroxol and bromhexine containing medicinal products. 2015. [Accessed 01 Apr. 2019] (online). Available from:
- Levosalbutamol, ambroxol, guaiphenesin [Patient Information Leaflet]. The Madras Pharmaceuticals; 2021. [Accessed 27 Oct. 2025] (online). Available from:
- Levosalbutamol Sulphate, Ambroxol Hydrochloride and Guaiphenesin [Summary of Product Characteristics]. Mumbai, India: 2023. [Accessed 25 Mar. 2026] (online). Available from:
Marketer details
Name: Medleaf Pharmaceuticals
Address: Plot No. 44, HSIDC, Kalka Ratpur Colony, Panchkula- 134102, Haryana
Country of origin: India
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₹72
Inclusive of all taxes
MRP₹79.69 10% OFF
100.0 ml in 1 bottle
SOLD OUT
Available alternative with same salt composition
Alkof LS Plus Cough Syrup
bottle of 100 ml Syrup
by Alkem Laboratories Ltd
Get by 11pm
₹114
12% off
Ambroxol (30mg) + Levosalbutamol (1mg) + Guaifenesin (50mg)