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food interaction for CLOSIS PLUS

alcohol interaction for CLOSIS PLUS

pregnancy interaction for CLOSIS PLUS

lactation interaction for CLOSIS PLUS

food
alcohol
pregnancy
lactation
Avoid Closis plus tablet with high-fat meals such as olive oil, nuts & seeds (Brazil nuts), dark chocolate, butter and meat.
UNSAFE
Closis plus tablet may cause excessive drowsiness and calmness with alcohol.
Taking Propranolol with alcohol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
UNSAFE
Closis plus tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Closis plus tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
UNSAFE

SALT INFORMATION FOR CLOSIS PLUS

Clonazepam(NA)

Uses

Clonazepam is used in the treatment of anxiety and alcohol withdrawal.

How it works

Clonazepam works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Common side effects

Sleepiness, Uncoordinated body movements, Slurred speech, Dizziness, Fatigue, Memory impairment, Irritability, Headache, Dry mouth, Depression, Constipation
Propranolol(NA)

Uses

Propranolol is used in the treatment of angina, arrhythmias, heart attack, increased blood pressure , anxiety and migraine.

How it works

Propranolol blocks the action of certain chemical messengers on the heart and blood vessels. This effect reduces heartbeat, blood pressure, and strain on the heart following a heart attack.

Common side effects

Nausea, Headache, Fatigue, Dizziness, Palpitations, Abdominal pain, Breathlessness, Diarrhoea, Slow heart rate, Constipation

SUBSTITUTES FOR CLOSIS PLUS

No substitutes found

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Expert advice FOR CLOSIS PLUS

  • Notify your doctor immediately if you are or are planning to become pregnant during the administration of this medicine.
     
  • Clonazepam may be addictive, so take it as prescribed by the doctor. 
  • Do not discontinue the use of Clonazepam, unless the doctor has advised you. Discontinuation may cause withdrawal symptoms, which may include seizures.
  • Clonazepam may cause memory problems, drowsiness, confusion, especially in elderly patients. 
  • Most people may find that it gets less effective over time. 
  • Avoid driving after taking Clonazepam as it may cause drowsiness, dizziness, and confusion. 
  • Avoid consuming alcohol when taking Clonazepam, it may cause excessive drowsiness. 

Frequently asked questions FOR CLOSIS PLUS

Clonazepam

Q. Is clonazepam stronger than lorazepam?
Clonazepam and lorazepam belong to the same category of medicines called benzodiazepines. Clonazepam is used to treat fits (epilepsy or seizures) and sudden, unexpected attacks of extreme fear, and worry about these attacks (panic disorder) with or without agoraphobia (fear of public places) while lorazepam is used to treat anxiety disorders. Always follow doctor’s advice regarding the use of these drugs.
Q. What is clonazepam used for?
Clonazepam is used to treat fits (epilepsy or seizures) and sudden, unexpected attacks of extreme fear, and worry about these attacks (panic disorder) with or without agoraphobia (fear of public places).
Q. Is clonazepam safe?
Clonazepam is safe if used at prescribed doses for the prescribed duration as advised by your doctor.melatonin
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Q. Is clonazepam an opiate?
No, clonazepam is not an opiate, it's a benzodiazepine.
Q. Can I take clonazepam with amoxicillin?
No interactions have been reported between clonazepam and amoxicillin. However, interactions may occur. Please consult your doctor if you are taking the two medicines together.
Q. Does clonazepam cause hair loss?
Clonazepam belongs to a group of medicines called benzodiazepines and these have been seen to cause hair loss. Please consult your doctor in case you experience excessive hair fall while taking clonazepam.
Q. Does clonazepam lower blood pressure?
Yes, clonazepam can lower blood pressure, as a side effect. Clonazepam has been reported to cause postural hypotension which means that a person's blood pressure falls when suddenly standing up from a lying or sitting position.
Q. Does clonazepam help you sleep?
Clonazepam can make you feel sleepy. However, clonazepam is not used for sleep. Please consult your doctor in case you have any difficulty to sleep.
Q. Does clonazepam cause weight gain?
No, there are no reports of clonazepam causing weight gain. Please consult your doctor if you experience weight gain while taking clonazepam.
Q. Does clonazepam lower heart rate?
Lowering of heart rate has not been reported with clonazepam. Please consult your doctor if you experience this problem while taking clonazepam.
Q. Does clonazepam expire?
Yes, clonazepam does expire. All the medicines come with an expiry date mentioned on the pack. You must check the expiry date before using any medicine.
Q. Does clonazepam get you high?
No, clonazepam does not get you high.
Q. Can I take clonazepam while taking melatonin?
Both clonazepam and melatonin have been seen to cause sedation (make you feel sleepy). Please consult your doctor before taking the two medicines together.
Q. Does clonazepam cause dementia?
No, clonazepam has not been reported to cause dementia. However, please consult your doctor in case you have any symptoms related to dementia,
Q. Can I take clonazepam with zolpidem?
Clonazepam and zolpidem can increase each other's effects. Please consult your doctor before taking the two medicines together.
Q. Can I take clonazepam with alprazolam?
Clonazepam and alprazolam both belong to the same class of medicines and both can increase sedation (make you feel sleepy) and this may effect your daily life activities like driving or working with a machine. Please consult your doctor before taking the two medicines together.
Q. Can I take clonazepam with oxycodone?
Clonazepam and oxycodone both increase sedation (make you feel sleepy) and this may effect your daily life activities like driving or working with a machine. Please consult your doctor before taking the two medicines together.
Q. Can I take clonazepam with trazodone?
Clonazepam and trazodone both increase sedation (make you feel sleepy) and this may effect your daily life activities like driving or working with a machine. Please consult your doctor before taking the two medicines together.
Q. Can I take clonazepam with gabapentin?
Clonazepam can be taken with gabapentin. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.
Q. Can I take clonazepam with alcohol?
Alcohol in combination with clonazepam may modify the effects of clonazepam and cause side-effects like excessive sleepiness or also decrease the action of clonazepam. Under no circumstances should alcohol be consumed while taking clonazepam. Please consult your doctor.
Q. Can I take clonazepam with paracetamol (acetaminophen)?
Clonazepam decreases levels of paracetamol (acetaminophen) by increasing metabolism. Please consult your doctor before taking the two medicines together.
Q. Can I take clonazepam with oxycodone?
Clonazepam and oxycodone both make you feel sleepy. Please consult your doctor before taking the two medicines together as it may effect your ability to drive or operate a machine or other daily life activities.
Q. Can I take clonazepam with sertraline?
Clonazepam can be taken with sertraline. No drug-drug interactions have been reported between the two. However, interactions may occur. Please consult your doctor before taking the two medicines together.
Q. Can I take clonazepam with escitalopram?
Clonazepam can be taken with escitalopram. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.
Q. Is clonazepam safe?
Yes, clonazepam is safe if taken for prescribed duration in prescribed doses as advised by your doctor.
Q. Is clonazepam antidepressant?
No, clonazepam is not an antidepressant. Clonazepam belongs to a group of drugs known as benzodiazepines which have anticonvulsive (helps to treat fits or seizures), sedative (makes you feel sleepy), muscle relaxing and anxiolytic (decreases anxiety) effects.
Q. Is clonazepam addictive?
Clonazepam can cause physical and psychological dependence. Please consult your doctor to know differences between dependence and addiction. Addiction-prone individuals (such as drug addicts or alcoholics) should be under careful surveillance when receiving clonazepam because of the predisposition of such patients to habituation and dependence.
Q. Is clonazepam a sedative?
Clonazepam is not primarily used as a sedative (for inducing sleep). However, it may have sedation (makes you feel sleepy) properties.
Q. Is clonazepam a sleeping pill?
No, clonazepam is not a sleeping pill. However, it may make you feel sleepy. Please talk to your doctor about your sleep related problems if any.
Q. Is clonazepam a narcotic?
Clonazepam is not a narcotic substance. Clonazepam belongs to a group of drugs known as 'benzodiazepines' which have anticonvulsive, sedative, muscle relaxing and anxiolytic effects.
Q. Is clonazepam safe in pregnancy?
Clonazepam is not safe to use during pregnancy as it may cause harm to the fetus (unborn child). Please consult your doctor if you are planning for pregnancy while taking clonazepam or you get pregnant while taking clonazepam.
Q. Is clonazepam banned in India?
No, clonazepam is not banned in India. However, it is available only when prescription by a doctor.
Q. Can I take clonazepam for anxiety?
Clonazepam is not recommended for treatment of anxiety. Please consult your doctor for the management of your anxiety.
Q. Can I take clonazepam for life?
Clonazepam should be taken for the duration as prescribed by your doctor.
Q. Can I take clonazepam with amphetamine?
Clonazepam can be taken with amphetamine. No drug-drug interactions have been reported between the two. However, interactions may occur. Please consult your doctor before taking the two medicines at the same time.
Q. How long can I take clonazepam for?
The prescribed duration of clonazepam varies depending on the condition or disease fo which this is given. Please take clonazepam for a duration as prescribed by your doctor.
Q. Can I take clonazepam for pain?
Clonazepam is not recommended for the management of pain. Please consult your doctor.
Q. What can I take for clonazepam withdrawal?
Clonazepam should not be stopped at once. Always decrease the dose of clonazepam slowly and only when advised by your doctor. Please consult your doctor if you experience clonazepam withdrawal.

Propranolol

Q. What is propranolol used for?
Propranolol is used in the treatment of angina (chest pain), arrhythmias (abnormal heartbeat), heart attack, increased blood pressure, anxiety, and migraine.
Q. Is propranolol over the counter product?
Propranolol is a prescription medicine and should only be taken for the proper indication in the appropriate dose, frequency, and duration as advised by a doctor.
Q. Is propranolol a monoamine oxidase inhibitor (MAO) inhibitor?
Propranolol is not a MAO inhibitor. It belongs to a class of drugs known as beta blockers.
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Q. Is propranolol safe to use?
Clinical studies have shown that propranolol is tolerated well even in long-term use and is safe. However, the drug is not devoid of side effects and should only be taken as per the doctor’s advice.
Q. Is propranolol safe in pregnancy?
There are no adequate studies establishing the safety of propranolol use in pregnancy. Its use has been associated with placental and congenital abnormalities and hence should generally be avoided during pregnancy. Consult your doctor regarding the use of the drug in pregnancy.
Q. Is propranolol a blood thinner?
Propranolol is not a blood thinner. It is a nonselective beta-adrenergic receptor blocker.
Q. Is propranolol a narcotic substance?
Propranolol is not a narcotic substance. It is a beta-blocker used in the treatment of diseases like hypertension and angina.
Q. Is propranolol ototoxic?
Propranolol is not associated with ototoxicity (harmful to the ear). However, if you experience any such problem while using the drug, talk to your doctor.
Q. Is propranolol a statin?
No, propranolol is not a statin. It is a nonselective beta-adrenergic receptor blocker.
Q. Is propranolol used to treat anxiety?
Propranolol is indicated for the treatment of anxiety. However, consult your doctor for the right treatment of anxiety.
Q. Can I take propranolol for headaches?
Propranolol is not used for the treatment of a headache. It is used to prevent an attack of a migraine headache. However, it is not known to stop the migraine headaches once started. Consult your doctor for the proper treatment of your headache.
Q. Can I take propranolol for irritable bowel syndrome (IBS)?
Propranolol is not indicated in the treatment of irritable bowel syndrome (IBS). Consult your doctor for the right treatment IBS.
Q. Can I take propranolol forever?
Propranolol is a prescription drug and should only be taken in the dose, frequency, and duration as advised by the doctor. However, clinical studies have shown that propranolol is tolerated well in long-term use and is generally safe.
Q. How long can I take propranolol for?
The dose, frequency, and duration of therapy with propranolol varies for different diseases. Consult your doctor for the right duration of use of propranolol.
Q. Can you take propranolol for depression?
Propranolol is not indicated for the treatment of depression. Please consult your doctor for the right treatment of depression.
Q. Can I take propranolol for a migraine headache?
Propranolol can be used as a to prevent an attack for migraine headaches. However, it is not known to stop the migraine headaches once started. Consult your doctor for the appropriate the appropriate therapy.
Q. Can I take propranolol with alprazolam?
Propranolol is not known to have any clinically meaningful interaction with alprazolam. However, interactions can occur. Please consult your doctor before taking both the drugs together.
Q. Can I take propranolol with lorazepam?
Propranolol is not known to have any clinically meaningful interaction with lorazepam. However, interactions can occur. Please consult your doctor before taking both the drugs together.
Q. Can I take propranolol without food?
Propranolol can be taken without food. However, taking the drug with food, especially high-protein food enhances the bioavailability (amount of drug which reaches the blood) of the drug.
Q. Can I take propranolol with aspirin?
Aspirin, especially if taken in high doses, may reduce the blood pressure lowering (antihypertensive) effect of propranolol. Talk to your doctor before taking the two medicines together.
Q. Can I take propranolol with gabapentin?
Propranolol is not known to have any interactions with gabapentin. However, interactions can occur. Talk to your doctor before taking both the medicines together.
Q. Can I take propranolol with amoxicillin?
Propranolol is not known to have any interaction with amoxicillin. However, interactions can occur. Talk to your doctor before taking both the medicines together.
Q. Is propranolol safe for long-term use?
Clinical studies have shown that propranolol is tolerated well even in long-term use and is safe. However, the drug is not devoid of adverse effects and should only be taken as per the doctor’s advice.
Q. Can I take propranolol with prednisone?
Anti-hypertensive (blood pressure lowering) effect of propranolol may decrease if taken with prednisone as prednisone can cause sodium and water retention. Talk to your doctor before taking both the medicines together.
Q. Does propranolol cause diabetes?
Propranolol is not known to cause diabetes. However, it can interfere with insulin secretion and it can also block the sympathetic response (signs and symptoms experienced by the patient) to hypoglycemia. Talk to your doctor in case you are prescribed propranolol and you have diabetes.
Q. Does propranolol work?
Propranolol is a nonselective beta-adrenergic receptor blocker which is used in the treatment of a variety of diseases like hypertension, angina, migraine, heart attack, tremors etc. It is a prescription drug which should only be used as per the doctor’s advice.
Q. Does propranolol make you sleepy?
Propranolol is not known to make you sleepy. It can, however, cause loss of sleep and dizziness rarely. Consult your doctor if you experience any such symptom.
Q. Does propranolol expire?
Propranolol, like any other drug, has an expiry date and should not be used beyond that period. The shelf life of propranolol is three years.
Q. Does propranolol cause depression?
Depression is a rare side effect of propranolol. If you experience any form of depression or associated symptoms while using the drug, consult your doctor.
Q. Does propranolol cause erectile dysfunction?
Propranolol use has been associated with erectile dysfunction (also known as impotence). Consult your doctor if you experience any such problem while using the drug.
Q. Does propranolol cause diarrhea?
Diarrhea is a rare side effect of propranolol. Consult your doctor if you experience such problem while using the drug.
Q. Does propranolol affect sleep?
Use of propranolol has been associated with sleep disturbances, especially insomnia (inability to fall asleep). Consult your doctor if you experience any sleep disturbance after taking propranolol.
Q. Does propranolol work immediately?
Propranolol, when taken orally, takes some time to get absorbed. The peak plasma concentration after an oral dose is achieved between one to four hours.
Q. Does propranolol raise blood sugar?
Propranolol can interfere with insulin secretion and can also block the sympathetic response (signs and symptoms experienced by the patient) to hypoglycemia. However, it is not known to significantly affect blood sugar values.

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Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)