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Clopam 1gm Injection

Pralidoxime (1gm)

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Product Summary :

Clopam 1gm Injection is an antidote used to treat organophosphate poisoning. It helps restore the activity of an enzyme affected by these chemicals, reducing their harmful effects on muscles and nerves. It is given by a healthcare professional, usually along with other medicine and supportive treatment. Possible side effects include nausea, headache, dizziness, blurred vision and increased blood pressure.

Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 08 Nov 2026 | 01:02 AM (IST)

₹291 MRP ₹316.618% off

(Inclusive of applicable taxes)

Gurgaon

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General Information

Contains

Pralidoxime (1gm)

Marketer

Chandra Bhagat Pharma Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Clopam 1gm Injection is a prescription medicine used in the treatment of poisoning caused by pesticides and chemicals that contain organophosphates. It is used in the cases where respiratory depression occurs as a result of muscle weakness due to poisoning.

Clopam 1gm Injection is administered in a medical emergency situation thus aim should be to seek treatment of poisoning without waiting for the results of laboratory tests. This injection is given under the supervision of a healthcare professional. Moreover, it is important to consult your doctor if you have abnormal heartbeat, difficulty or trouble with breathing, increased muscle weakness, or severe tiredness after receiving this medicine.

There can be some side effects like nausea, muscle weakness, headache, double vision, and blurred vision. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you will better. This medicine may also increase your blood pressure, so it is better to consult your doctor if it bothers you.

Uses of Clopam Injection

Organophosphate poisoning

Benefits of Clopam Injection

Organophosphate poisoning
Organophosphates are used as insecticides or medications. Symptoms of organophosphate poisoning include increased saliva and tear production, diarrhea, vomiting, small pupils, sweating, muscle tremors, and confusion. Clopam 1gm Injection helps to undo the effects of organophosphate poisoning and to restore normal life functions. It is given as an injection by a doctor or nurse.

Side effects of Clopam Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clopam

Accomodation disorder
Dizziness
Double vision
Drowsiness
Headache
High blood pressure
Increased heart rate
Muscle weakness
Nausea

How to use Clopam Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Clopam Injection works

Clopam 1gm Injection helps restore the activity of an enzyme called acetylcholinesterase, which is blocked by organophosphates. This helps reduce the harmful effects of excessive acetylcholine, particularly muscle weakness and breathing difficulties caused by the poisoning. It is usually given when supportive treatment, as required.

Dosage

Clopam 1gm Injection is given by a healthcare professional in a hospital or emergency-care setting. The dose depends on severity of poisoning and the patient's response. It is usually given as an injection into the vein.

Quick tips

Clopam 1gm Injection is given as an injection into veins, muscles or under the skin by a doctor only.
Your doctor will monitor you closely for a period of 72 hours after giving the medicine.
Your doctor will closely monitor your heart rate, blood pressure, breathing rate and oxygen level during the treatment.
It may cause temporary blurring of your vision. Do not drive or do anything that requires concentration until you know how it affects you.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Clopam 1gm Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Clopam 1gm Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Clopam 1gm Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Clopam 1gm Injection may cause temporary visual disturbances. Do not drive until your vision is clear.

Kidney

CAUTION

Clopam 1gm Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Clopam 1gm Injection in patients with liver disease.

Frequently asked questions

What is Clopam 1gm Injection used for?

Clopam 1gm Injection is an antidote used to treat poisoning caused by organophosphate pesticides and certain nerve agents. It helps restore muscle and nerve function affected by the poisoning.

Is Clopam 1gm Injection given alone to treat organophosphate poisoning?

No. Clopam 1gm Injection is generally given along with atropine and supportive medical treatment. The treatment plan depends on the severity of poisoning and the patient's condition.

How is Clopam 1gm Injection given?

It is given by a healthcare professional, preferably through a vein. If intravenous administration is not possible, it may be given into a muscle or under the skin, depending on the clinical situation.

How soon should Clopam 1gm Injection be given after organophosphate poisoning?

Treatment should begin as early as possible. Delaying treatment can reduce its effectiveness. Medical treatment should not be delayed while waiting for laboratory test results.

Can Clopam 1gm Injection affect vision?

Yes. It may temporarily cause blurred vision, double vision or difficulty focusing. Inform your healthcare professional if these symptoms occur.

Can Clopam 1gm Injection cause an increase in blood pressure or heart rate?

Yes. It may temporarily increase blood pressure or heart rate. Your healthcare team will monitor these during treatment.

Fact Box

Chemical Class

N- methylpyridinium compounds

Habit Forming

Therapeutic Class

OTHERS

Action Class

Cholinesterase Reactivator

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1139-40.
Pralidoxime. Deerfield, IL: Baxter Healthcare Corporation; 2010. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Pralidoxime chloride. Deerfield, IL: Baxter Healthcare Corporation; 2026. [Accessed 22 Apr. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Chandra Bhagat Pharma Pvt Ltd
Address: 501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071

Vendor Details

Country of origin: India

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Clopam 1gm Injection

Clopam 1gm Injection

Product Summary :

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Clopam Injection

Benefits of Clopam Injection

Side effects of Clopam Injection

How to use Clopam Injection

How Clopam Injection works

Dosage

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Clopam 1gm Injection used for?

Is Clopam 1gm Injection given alone to treat organophosphate poisoning?

How is Clopam 1gm Injection given?

How soon should Clopam 1gm Injection be given after organophosphate poisoning?

Can Clopam 1gm Injection affect vision?

Can Clopam 1gm Injection cause an increase in blood pressure or heart rate?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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