Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clonasig Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.
Clonasig Plus Tablet is a combination of two medicines: Clonazepam and escitalopram which have anxiety-lowering and mood-enhancing effects. Clonazepam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Escitalopram is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood.
Clonasig Plus Tablet may cause excessive drowsiness and calmness with alcohol.
WEIGH RISKS VS BENEFITS
Clonasig Plus Tablet is unsafe to use during pregnancy. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Clonasig Plus Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Clonasig Plus Tablet may cause side effects which could affect your ability to drive.
Clonasig Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Clonasig Plus Tablet may not be needed in these patients. Please consult your doctor. Use of Clonasig Plus Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Clonasig Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Clonasig Plus Tablet may be needed. Please consult your doctor.