Clomiserm Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 16 Feb 2026 | 03:30 PM (IST)

Clomiserm Tablet is a medicine used to treat female infertility associated with ovulation disorders. It helps induce ovulation in women who have irregular or absent egg release, including those with polycystic ovary syndrome (PCOS) or unexplained infertility.

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General Information

Contains

Clomiphene (100mg)+ Melatonin (3mg)

Marketer

Medgrow Health Care

Storage

Store below 30°C

The content is shown in English

Product introduction

Clomiserm Tablet should be taken as advised by your doctor, preferably at the same time each day. It is usually taken for a specific number of days during the menstrual cycle as prescribed by the doctor. Regular monitoring, including ultrasound or hormonal assessment, may be required to evaluate ovarian response.

Common side effects of Clomiserm Tablet include hot flashes, headache, nausea, breast tenderness, and mood changes. Some women may experience dizziness or visual disturbances. Stop taking the medicine and inform your doctor immediately if you develop severe abdominal pain or vision problems.

Before taking Clomiserm Tablet, inform your doctor if you have liver disease, thyroid or adrenal disorders, ovarian cysts unrelated to PCOS, or any known allergies. Also, inform your doctor about all other medicines you are taking, as they may affect the treatment. This medicine is contraindicated during pregnancy and should not be used if you are pregnant or suspect pregnancy.

Uses of Clomiserm Tablet

Treatment of Female infertility

Benefits of Clomiserm Tablet

Treatment of Female infertility
Clomiserm Tablet helps induce ovulation in women who have difficulty becoming pregnant due to problems with egg release from the ovary, such as in polycystic ovary syndrome (PCOS). It promotes follicular development and supports the maturation of eggs, which may help improve fertility outcomes. It also provides antioxidant support that helps improve oocyte (egg) quality and supports healthy ovarian function.

Side effects of Clomiserm Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clomiserm

Hot flashes
Headache
Breast tenderness
Mood swings
Nausea

How to use Clomiserm Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clomiserm Tablet may be taken with or without food.

How Clomiserm Tablet works

Clomiserm Tablet is a combination of two medicines: clomiphene and melatonin, which help treat female infertility. Clomiphene is a selective estrogen receptor modulator (SERM) that stimulates the release of gonadotropins (FSH and LH) from the pituitary gland, promoting follicular development and ovulation. Melatonin regulates the sleep–wake cycle and has antioxidant properties that support ovarian function and help improve oocyte (egg) quality.

All substitutes for Clomiserm Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Clomiserm Tablet is prescribed to help induce ovulation in women with ovulation-related infertility.
Take the medicine exactly as prescribed and at the same time each day.
Monitoring through ultrasound or hormonal tests may be required during treatment.
Inform your doctor immediately if you experience severe abdominal pain or vision problems.
Follow your doctor’s instructions carefully regarding the timing of treatment during the menstrual cycle.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Clomiserm Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Clomiserm Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Clomiserm Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Clomiserm Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Clomiserm Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Clomiserm Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

How and in what dose should I take Clomiserm Tablet?

Take Clomiserm Tablet exactly in the dose and duration prescribed by your doctor. It is usually taken for a specific number of days during the menstrual cycle, often starting early in the cycle as advised by your physician. Do not change the dose or timing on your own, as correct scheduling is important for successful ovulation induction.

After how many days of taking Clomiserm Tablet should I have intercourse to improve the chances of pregnancy?

Ovulation generally occurs several days after completing the prescribed course of treatment. Your doctor may recommend having intercourse during the fertile window, usually about 5–10 days after starting the medicine, depending on your cycle. Regular monitoring through ultrasound or hormonal tests may be done to identify the most suitable days.

For how many cycles can I take Clomiserm Tablet?

Treatment may be repeated across menstrual cycles if pregnancy does not occur, depending on your doctor’s assessment. However, treatment is usually limited to a few cycles to reduce the risk of side effects and to reassess the response to therapy. Always follow your doctor’s advice regarding continuation or discontinuation of treatment.

What are the common side effects of Clomiserm Tablet?

Common side effects include hot flashes, headache, nausea, breast tenderness, mood changes, or mild abdominal discomfort. These effects are usually temporary and improve after treatment is completed. Consult your doctor if symptoms are severe, persistent, or troubling.

Why is monitoring required while taking Clomiserm Tablet?

Your doctor may perform ultrasound scans or hormone tests to monitor how your ovaries respond to treatment. This helps confirm ovulation and reduces the risk of complications such as ovarian hyperstimulation. Monitoring also helps determine the best timing for conception.

Should Clomiserm Tablet be taken if I am already pregnant?

No, Clomiserm Tablet should not be used during pregnancy. Treatment is usually started only after confirming that you are not pregnant. Inform your doctor immediately if you suspect pregnancy while taking this medicine.

Can lifestyle changes improve the effectiveness of Clomiserm Tablet?

Yes, maintaining a healthy weight, following a balanced diet, managing stress, and getting adequate sleep may help improve fertility outcomes. Following your doctor’s advice, along with treatment, can support better overall reproductive health.

Fact Box

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

References

Clomiphene+Melatonin [Prescribing Information]. Panchkula, Haryana: Cafoli Lifecare Pvt. Ltd. [Accessed 16 Feb. 2026] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Medgrow Health Care
Address: 18/447,Ambadi Venoli Road, Mandrikad Kallepully Po Palakkad Kl 678005 India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Clomiserm Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Clomiserm Tablet

Benefits of Clomiserm Tablet

Side effects of Clomiserm Tablet

How to use Clomiserm Tablet

How Clomiserm Tablet works

All substitutes for Clomiserm Tablet

E-Ova M 100 Tablet

Angelova 100 Tablet

N Clomi Plus 100mg/3mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

How and in what dose should I take Clomiserm Tablet?

After how many days of taking Clomiserm Tablet should I have intercourse to improve the chances of pregnancy?

For how many cycles can I take Clomiserm Tablet?

What are the common side effects of Clomiserm Tablet?

Why is monitoring required while taking Clomiserm Tablet?

Should Clomiserm Tablet be taken if I am already pregnant?

Can lifestyle changes improve the effectiveness of Clomiserm Tablet?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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