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Cilnep-CH Tablet

Cilnidipine (10mg)+ Chlorthalidone (12.5mg)

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Cilnep-CH Tablet is a combination of medicines used in the treatment of hypertension (high blood pressure). It also helps to reduce the risk of stroke and heart attack.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Mar 2026 | 12:43 PM (IST)

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General Information

Contains

Cilnidipine (10mg)+ Chlorthalidone (12.5mg)

Marketer

Leeford Healthcare Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Cilnep-CH Tablet should be taken with food, preferably in the morning, to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight, and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

Glucose intolerance, ankle swelling, headache, tiredness, and decreased potassium levels are some common side effects of this medicine. Consult your doctor if any of these bother you, or get worse, or do not go away.  Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. Dizziness or headache may occur due to low blood pressure, hence rise slowly from the sitting position or avoid driving.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking, especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function, level of electrolytes, and blood sugar level checked regularly to make sure that this medicine is working properly.

Uses of Cilnep-CH Tablet

Treatment of Hypertension (high blood pressure)

Benefits of Cilnep-CH Tablet

Treatment of Hypertension (high blood pressure)
Cilnep-CH Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Cilnep-CH Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cilnep-CH

Glucose intolerance
Sleepiness
Ankle swelling
Headache
Flushing (sense of warmth in the face, ears, neck and trunk)
Tiredness
Palpitations
Nausea
Increased blood uric acid
Decreased potassium level in blood
Altered blood lipid level

How to use Cilnep-CH Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cilnep-CH Tablet should be taken with or after food.

How Cilnep-CH Tablet works

Cilnep-CH Tablet is a combination of two medicines: cilnidipine and chlorthalidone. Cilnidipine is a calcium channel blocker that relaxes blood vessels and makes the heart more efficient at pumping blood throughout the body. Chlorthalidone is a diuretic that removes extra water and certain electrolytes from the body by increasing the amount of urine produced. Over time, it also works by relaxing blood vessels and improving blood flow.

All substitutes for Cilnep-CH Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Cilnep-CH Tablet helps in the treatment of high blood pressure.
It also lowers your risk of stroke and heart attack.
Take it in the morning with breakfast to avoid getting up at night to urinate.
It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
It may cause you to feel lightheaded or weak especially when you stand up (orthostatic hypotension). Rise slowly if you have been sitting or lying down.
It may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Cilnep-CH Tablet.

Pregnancy

UNSAFE

Cilnep-CH Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Cilnep-CH Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Cilnep-CH Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Cilnep-CH Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Cilnep-CH Tablet is not recommended in these patients.

Liver

UNSAFE

Cilnep-CH Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Cilnep-CH Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

What is Cilnep-CH Tablet used for?

Cilnep-CH Tablet is used to treat high blood pressure (hypertension). By lowering blood pressure, it helps reduce the risk of heart attack, stroke, and kidney damage.

Who should not take Cilnep-CH Tablet?

Do not take Cilnep-CH Tablet if you are allergic to cilnidipine, chlorthalidone, or any ingredients present in it. It is also contraindicated in individuals with severe kidney or liver disease, blocked bile ducts, very low potassium or sodium levels, gout, or untreated Addison’s disease.

Can Cilnep-CH Tablet affect my heart?

Yes. Cilnep-CH Tablet may cause low blood pressure, dizziness, irregular heartbeat, or worsen certain heart conditions, such as a recent heart attack, unstable angina, or severe aortic stenosis. Use only under medical supervision.

What are the serious side effects of Cilnep-CH Tablet?

Serious side effects may include chest pain, severe dizziness or fainting, very low blood pressure, worsening heart failure, jaundice (yellowing of the skin or eyes), allergic swelling, kidney failure, or severe electrolyte imbalance. Seek immediate medical attention if you experience any of these symptoms.

Can Cilnep-CH Tablet cause electrolyte imbalance?

Yes. Cilnep-CH Tablet may lower potassium, sodium, or magnesium levels, and raise calcium or uric acid levels. This can lead to weakness, muscle cramps, gout, or irregular heartbeat.

Is Cilnep-CH Tablet safe for people with kidney problems?

No. Cilnep-CH Tablet is not recommended for individuals with severe kidney disease or those unable to pass urine. In mild to moderate kidney impairment, it should be used cautiously with regular monitoring.

Is Cilnep-CH Tablet safe for people with liver problems?

Cilnep-CH Tablet should not be used in cases of severe liver disease, bile duct obstruction, or jaundice. In mild liver conditions, it may be used with caution and close monitoring.

Can I drink grapefruit juice while taking Cilnep-CH Tablet?

No. Grapefruit juice should be avoided while taking Cilnep-CH Tablet, as it can increase the effect of cilnidipine and cause excessive lowering of blood pressure.

Can Cilnep-CH Tablet cause gout or high uric acid?

Yes. Cilnep-CH Tablet may raise uric acid levels in the blood, potentially triggering gout attacks. Individuals with a history of gout should use this medicine cautiously.

Can Cilnep-CH Tablet affect blood sugar and cholesterol?

Yes. Cilnep-CH Tablet may increase blood sugar, cholesterol, and triglyceride levels in some patients. If you have diabetes or high cholesterol, regular monitoring is advised.

What precautions should I take while using Cilnep-CH Tablet?

Do not stop taking Cilnep-CH Tablet suddenly unless advised by your doctor. Avoid driving, working at heights, or operating machinery if you feel dizzy. Your doctor should regularly monitor your blood pressure, kidney and liver function, and electrolyte levels during treatment.

Fact Box

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)Pure & Cure Healthcare Pvt. Ltd. (A subsidiary of Akums Drugs & Pharmaceuticals Ltd.)
Address: A)Plot No. 26A, 27-30, Sector-8A, I.I.E., SIDCUL, Ranipur, Haridwar-249 403, Uttarakhand/Vill. Manakpur, P.O. Lodhimajra, Baddi-173 205, Distt.-Solan, (H.P.)

Marketer details

Name: Leeford Healthcare Ltd
Address: 203, Mangalam, Kulupwadi, Borivali (E), Mumbai-400066

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Cilnep-CH Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Cilnep-CH Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Cilnep-CH Tablet

Benefits of Cilnep-CH Tablet

Side effects of Cilnep-CH Tablet

How to use Cilnep-CH Tablet

How Cilnep-CH Tablet works

All substitutes for Cilnep-CH Tablet

Nexovas CH Tablet

Cilacar C Tablet

CTD-C 12.5/10 Tablet

Ciledge CT 12.5mg Tablet

Natcocil-CT Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Cilnep-CH Tablet used for?

Who should not take Cilnep-CH Tablet?

Can Cilnep-CH Tablet affect my heart?

What are the serious side effects of Cilnep-CH Tablet?

Can Cilnep-CH Tablet cause electrolyte imbalance?

Is Cilnep-CH Tablet safe for people with kidney problems?

Is Cilnep-CH Tablet safe for people with liver problems?

Can I drink grapefruit juice while taking Cilnep-CH Tablet?

Can Cilnep-CH Tablet cause gout or high uric acid?

Can Cilnep-CH Tablet affect blood sugar and cholesterol?

What precautions should I take while using Cilnep-CH Tablet?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Manufacturer details

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests