Chrono Tablet is a combination of two medicines used to treat epilepsy, a neurological disorder in which there are recurrent episodes of seizures or fits. It controls the abnormal activity of the brain, relaxes the nerves and hence, prevents seizures or fits.
Chrono Tablet should be taken with food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.
The most common side effects of this medicine are nausea and tremor. In some people, it may also cause other side effetcs like vomiting, headache, liver injury, and upper abdominal pain. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects.
Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression or suicidal thoughts. Also let your doctor know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, Chrono Tablet can be taken if it is clearly needed but the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.
You should avoid alcohol while taking Chrono Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Chrono Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Side effects of Chrono Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Chrono
Nausea
Tremors
How to use Chrono Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Chrono Tablet should be taken with or after food.
How Chrono Tablet works
Chrono Tablet is a combination of two antiepileptic medicines: Sodium Valproate and Valproic Acid.
Safety advice
Alcohol
CAUTION
Alcohol should be used with caution while taking Chrono Tablet.
Pregnancy
UNSAFE
Chrono Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
CONSULT YOUR DOCTOR
Chrono Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Chrono Tablet may cause side effects that could affect your ability to drive.
Kidney
CAUTION
Chrono Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
UNSAFE
Chrono Tablet is unsafe to use in patients with liver disease and should be avoided.
What if you forget to take Chrono Tablet?
If you miss a dose of Chrono Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed Chrono Tablet for treatment and prevention of seizures.
Take it at the same time every day to maintain consistent levels in your body.
Do not drive or do anything that requires mental focus until you know how Chrono Tablet affects you.
Avoid consuming alcohol when taking Chrono Tablet, as it may cause excessive sleepiness or drowsiness.
Monitor your weight during the treatment as Chrono Tablet can cause weight gain.
Your doctor may monitor Chrono Tablet level, blood counts and liver function regularly throughout your treatment. Inform your doctor if you develop fever, stomach pain, nausea or yellowing of your eyes or skin.
Do not take Chrono Tablet if you are pregnant or planning to conceive or breastfeeding.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
Patient concerns
Please suggest substitute of Levipil 500, It causes irratible behavior in my ADHD child also suffering from Epilepsy. He is taking Risperidone 0.75 mg from 2009. He is taking Levipil 500 and Lobazam 10 mg from 11th April 2016. Initially also, Irratibility was there but according to Doctor, it will be ok after few days
I am suffering from headache and vomiting for 3 years. I have done C.T scan of brain, E.E.G., E.C.G. blood test. Its all reports is normal. I was Senseless for 2 times, and Hands and feet were twisted. At present i am very suffering from headache and vomiting. I was visit ENT specialist. He said, no problem in my nose. Some dr. Said its migrane, nerve pain, tension, cynus, etc. But all medicine is do not work. I have no idea what is doing me. Please tell me.
?? ???? ?????? ?? ?????? ?? ?? ??? encorate Charon 200 500 tablet use krta hu kya iska koi solution h Jisse main completely thk ho jau
Dr. Jyoti Kapoor Madan
Psychiatry
Epilepsy requires regular treatment with anticonvulsants like encorate chrono for at least 3 years of seizure free period after which medicines may be tapered off unless seizures reappear. At present, there are no other effective treatment options.
I am taking zeptol CR 400 in morning and night. I have been taking this tablet for 10 years. I am newly married, 6 months old and we are planning for baby now. Is zeptol cr 400 a birth control tablet. Earlier i took epilex chrono 300 and gardenal 60mg. Now i had stopped both tables as doctor advised and taking zeptol Cr 400 alone. Please advice me whether Zeptol is a safe tablet while planning for pregnancy and want to know is it like a birth control tablet. Please help
Dr. Suman Rao
Obstetrics and Gynaecology
its not a birth control pill.it is usually prescribed for epilepsy. you can continue taking it if required.
Can the use of Chrono Tablet cause sleepiness or drowsiness?
Yes, Chrono Tablet may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities. Inform your doctor if you experience such an episode while taking this medicine.
Can I drink alcohol while taking Chrono Tablet?
No, avoid drinking alcohol while taking Chrono Tablet. Drinking alcohol will increase the side effects caused by Chrono Tablet.
Can Chrono Tablet be stopped when epilepsy symptoms are relieved?
No, Chrono Tablet should be continued as advised by the doctor. Stopping Chrono Tablet suddenly may cause the symptoms to reappear that too with increased frequency. If any problems are experienced due to Chrono Tablet, consult the doctor for re-evaluation.
Will a higher than the recommended dose of Chrono Tablet be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.
What are the instructions for the storage and disposal of Chrono Tablet?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Linde M, Mulleners WM, Chronicle EP, et al. Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults. Cochrane Database Syst Rev. 2013;(6):CD010611. [Accessed 23 Apr. 2019] (online) Available from:
Sodium Valproate and Valproic Acid [Package Information]. Gangtok, Sikkim: TORRENT PHARMACEUTICALS LTD.; 2022. [Accessed 28th Sept. 2023] (online) Available from:
Marketer details
Name: Icon Life Sciences
Address: Icon Life Sciences, Div. Of Mesmer Pharmaceuticals, No.202/6, Lane In.30, Phase-II, IDA, Cherlapally, Hyderabad, 500 051 AP
