


Chemophos 500mg Injection
Product Summary :
Chemophos 500mg Injection is given before certain cancer treatments to reduce kidney damage from cisplatin in patients with advanced ovarian cancer or to lower the risk of moderate to severe dry mouth after surgery and radiotherapy for head and neck cancer. It is given into a vein under medical supervision.Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 13 Nov 2026 | 07:55 AM (IST)
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General Information



Product introduction
Chemophos 500mg Injection is given as an injection into a vein (IV infusion) under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need it. This will depend on what you are being treated for. It is given shortly before chemotherapy or radiotherapy. Do not attempt to administer it yourself. Taking it incorrectly can cause serious side effects.
Nausea, vomiting, and decreased blood pressure are common side effects. Consult your doctor if these do not go away or bother you. Adequate hydration is important before receiving this medicine. Your blood pressure will be checked before and during the infusion, usually every 5 minutes.
Before receiving it, tell your doctor if you have heart disease, such as an irregular heartbeat or heart failure, or take medicines for high blood pressure. Many other medicines can affect, or be affected by, this medicine, so let your doctor know about all medicines you are taking. Seek immediate help if you develop a severe rash, skin peeling, swelling or difficulty breathing.
Uses of Chemophos Injection
Benefits of Chemophos Injection
Chemophos 500mg Injection is used to reduce moderate to severe dryness in the mouth caused by radiation treatment after surgery for head and neck cancer. It also helps reduce kidney damage from repeated cisplatin treatment in patients with advanced ovarian cancer. It is given as an injection by a doctor and should not be self-administered.
Side effects of Chemophos Injection
- Hypotension (low blood pressure)
How to use Chemophos Injection
How Chemophos Injection works
Dosage
Chemophos 500mg Injection is given as an injection into a vein by a doctor. The dose and timing depend on whether it is being used to protect the kidneys during chemotherapy or reduce dry mouth during radiotherapy. It is given shortly before the cancer treatment. Follow the treatment schedule prescribed by your doctor.
Quick tips
- Chemophos 500mg Injection is given as an infusion into the vein ( IV infusion) under the supervision of a doctor only.
- It is advisable to stay hydrated or drink plenty of fluids before taking medicine.
- Chemophos 500mg Injection may lower blood pressure. Your blood pressure may be checked before and every 5 minutes during the infusion.
- It may cause a decrease in calcium levels. Your doctor may monitor your calcium levels regularly and prescribe supplements if needed.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
Interaction with drugs
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 50-51.
- Amifostine. Nijmegen, Netherlands: USB Pharma B.V.; 1999. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
- Amifostine. Malvern, PA: Clinigen, Inc.; 2024. [Accessed 09 Sep. 2026] (online). Available from:
- Amifostine. Malvern, PA: Legacy Pharma USA Inc.; 2026. [Accessed 02 Nov 2026] (online). Available from:
- ETHYOL (amifostine) for injection. US Prescribing Information. Legacy Pharma USA Inc.; label available 2026. [Accessed 13 Nov. 2026] (online).
- Amifostine. National Cancer Institute Drug Information. National Cancer Institute. [Accessed 13 Nov. 2026] (online).




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Address: Cytogen Pharmaceuticals India Pvt. Ltd., 105, Anupam Plaza, 6, Local shopping Complex Gazipur, Delhi-96.
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Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)














