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Composition for CEFI L

Cefixime(400 mg),Levofloxacin(500 mg)

food interaction for CEFI L

alcohol interaction for CEFI L

pregnancy interaction for CEFI L

lactation interaction for CEFI L

Avoid Cefi l 400mg/500mg tablet with dairy products such as milk, cheese, curd, butter, paneer and ice cream.
Interaction with alcohol is unknown. Please consult your doctor.
Cefi l 400mg/500mg tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Cefixime(400 mg)


Cefixime is used to treat a variety of bacterial infections, particularly those of the ear, nose, sinuses (sinusitis), throat (pharyngitis, tonsillitis), chest and lungs (bronchitis, pneumonia), and the urinary system (cystitis, kidney infections). 

How it works

Cefixime is a cephalosporin antibiotic which acts by inhibiting bacterial cell wall (outer coating of bacteria) synthesis and killing the bacteria, thereby reducing the infection.

Common side effects

Allergic skin rash, Diarrhoea, Shortness of breath, Difficulty in swalloing, Headache, Itching, Stomach upset, Vaginal infection, Vomiting, Wheezing
Levofloxacin(500 mg)


Levofloxacin is used to treat bacterial infections of the respiratory tract, urinary tract, ear, tooth and prostate gland. It is also used to treat skin and soft tissue infections, anthrax and plague.

How it works

Levofloxacin belongs to a group of antibiotics called fluoroquinolones that kills a wide range of infection causing bacteria, both gram positive and gram negative. It acts by inhibiting bacterial DNA formation that is essential for bacterial growth and survival, thereby killing the bacteria.

Common side effects

Muscle pain, Joint pain, Bruise, Bleeding, Constipation, Diarrhoea, Headache, Heartburn, Nausea, Stomach pain, Vaginal itching, Vaginal discharge, Vomiting


No substitutes found

Expert advice for CEFI L

  • Take caution when taking the medicine if you have liver or kidney disease or history of anemia.
  • Take the tablets whole with a glass of water with or without food or milk. Do not crush or chew the tablets.
  • The medicine works best if taken with meal or within 30 minutes of a meal.
  • Talk to your doctor if you have kidney problems, inflammation of colon (colitis) or if you are taking medicines to thin the blood (e.g. warfarin).
  • Do not take cefixime if you are allergic to it or to any type of cephalosporin or penicillin drugs.
  • Do not take cefexime if you have allergic reaction (rash, swallowing or breathing problems, swelling of lips, face, tongue and throat).
  • Do not give cefixime to a child less than 6 months of age.

Frequently asked questions for CEFI L


Q. What is cefexime and what is it used for?
Cefexime (also available as Topcef/ Taxem/ Mahacef/ Zifi/ Suprax) is a cephalosporin antibiotic used for a variety of infections of the throat, chest and urinary tract and infections like typhoid or gonorrhea.
Q. Is cefixime same as penicillin?
It is not penicillin.

Q. Does it contain sulfur?
It  does not contain sulfur.
Q. Does cefexime affect birth control?
There is no evidence of cefexime affecting contraception. Please consult your doctor to confirm whether you require a secondary birth control measure while taking levofloxacin.


Q. Does levofloxacin/ L-cin 500/ Levomac/ Levoday/ Levobact contain penicillin or sulpha?
No, levofloxacin belong to a different group of antibiotics called fluoroquinolones. It does not contain penicillin or sulpha.
Q. Is levofloxacin gluten free?
Yes, levofloxacin sold as generic is gluten free. 
Q. Is levofloxacin the same as ciprofloxacin?
They belong to same class of antibiotics, but are different drugs.
Q. Is levofloxacin a narcotic?
No. Levofloxacin is not a narcotic drug.
Q. Can I take levofloxacin for sore throat, tonsil and strep throat?
Yes. Levofloxacin can be used to treat sore throat, tonsillitis and strep throat infections. Please consult your doctor before taking drug.
Q. Can I take levofloxacin with Tylenol/ Nyquil/ Benadryl/ Nexium/ Claritin?
Yes. You can take levofloxacin with Tylenol/ Nyquil/ Benadryl/ Nexium/ Claritin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Does levofloxacin cover Methicillin-resistant Staphylococcus aureus?
No. Levofloxacin is not effective against Methicillin-resistant Staphylococcus aureus.
Q. Does levofloxacin affect birth control?
No. Levofloxacin does not affect birth control pills. Please consult your doctor to confirm whether you require a secondary birth control measure while taking levofloxacin.

Top Medicines Prescribed with CEFI L 400MG/500MG TABLET


Content on this page was last updated on 10 March, 2016, by Dr. Varun Gupta (MD Pharmacology)