




Calsmooth Lotion
Calamine (8% w/v)+ Diphenhydramine (1% w/v)+ Camphor (0.1% w/v)
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Calsmooth Lotion is a prescription medicine used to treat allergic skin conditions. It works by blocking the effects of a chemical messenger (histamine), and provide relief from symptoms of skin allergy such as skin irritation.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 03 Sep 2026 | 01:01 AM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 03 Sep 2026 | 01:01 AM (IST)
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Get up to ₹75 cashback on a minimum order value (MOV) of ₹499 and above, valid once per customer.
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Get up to ₹75 cashback on a minimum order value (MOV) of ₹499 and above, valid once per customer.
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Flat Rs.150 on a Min Transaction of Rs.1000.
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General Information
Contains
Calamine (8% w/v)+ Diphenhydramine (1% w/v)+ Camphor (0.1% w/v)
Marketer
Lupin Ltd
Storage
Store below 30°C
The content is shown in English





Product introduction
Calsmooth Lotion should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. It is for external use only.
Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies to this medicine. This medicine is generally safe to use and has minimal or no side effects.
However, if you experience rashes or itching or any other symptoms which you think are because of this medicine, please consult your doctor. Inform your doctor if you are pregnant or breastfeeding or are suffering from any other disease.
Uses of Calsmooth Lotion
Benefits of Calsmooth Lotion
Allergic skin conditions
Calsmooth Lotion gives relief from itching, dryness and irritation associated with various allergic skin problems. It gives a cooling and a soothing effect when applied over rashes. It is also used to temporarily relieve pain caused by insect bites, minor burns, cuts and sunburn. Apply 2-3 times in a day or as prescribed. You may see an improvement in your skin after 2-3 weeks of using Calsmooth Lotion.
Calsmooth Lotion gives relief from itching, dryness and irritation associated with various allergic skin problems. It gives a cooling and a soothing effect when applied over rashes. It is also used to temporarily relieve pain caused by insect bites, minor burns, cuts and sunburn. Apply 2-3 times in a day or as prescribed. You may see an improvement in your skin after 2-3 weeks of using Calsmooth Lotion.
Side effects of Calsmooth Lotion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Calsmooth
- Limited data available
How to use Calsmooth Lotion
This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.
How Calsmooth Lotion works
Calsmooth Lotion is a combination of two astringents (Calamine and Camphor) and an antiallergic (Diphenhydramine). The astringents work by imparting a cooling sensation on the skin to relieve minor skin irritation. The antiallergic works by blocking the effects of a chemical messenger (histamine), thereby relieving symptoms of skin allergy.
Quick tips
- Calsmooth Lotion is used to treat itching and skin irritation due to allergies.
- Before you applythis medicine, wash the skin with a mild soap (preferably non -scented) and water. Allow the skin to dry completely.
- Apply Calsmooth Lotion directly to the skin and rub in gently. You may also use a cotton ball to smooth the medicine onto your skin. Wash your hands after applying.
- Do not cover the area being treated with airtight dressings such as bandages unless directed by the doctor. Allow the medicine to dry on its own.
Safety advice

Alcohol
No interaction found/established

Pregnancy
SAFE IF PRESCRIBED
Calsmooth Lotion is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding
SAFE IF PRESCRIBED
Calsmooth Lotion may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established

Frequently asked questions
Calsmooth Lotion is used to relieve itching, skin irritation, redness, and minor rashes caused by conditions such as insect bites, prickly heat, mild allergic skin reactions, and other minor skin irritations. It provides a soothing and cooling effect on the skin, helping reduce discomfort and the urge to scratch.
Calsmooth Lotion contains Calamine, Diphenhydramine, and Camphor. Calamine helps soothe irritated skin and reduce itching, while Diphenhydramine helps relieve allergic skin symptoms. Camphor provides a cooling sensation that helps calm irritation and makes the affected area feel more comfortable.
Clean and dry the affected area before application. Shake the bottle well, apply a thin layer to the affected skin, and allow it to dry naturally. Wash your hands after application unless your hands are the area being treated.
Yes, Calsmooth Lotion may be applied as directed by your doctor or according to the instructions on the product label. The frequency of application may vary depending on the severity of the itching or irritation and the area being treated.
Yes. Calsmooth Lotion can help soothe itching, redness, and irritation caused by insect bites and stings. The cooling effect may provide quick comfort, while the anti-itch ingredients help reduce the urge to scratch the affected area.
Yes, Calsmooth Lotion may help relieve the itching, burning sensation, and discomfort associated with prickly heat and mild heat rashes. Its cooling and soothing properties can help make the skin feel more comfortable during hot and humid weather.
Yes, doctors may recommend calamine-based lotions to help reduce itching associated with chickenpox. Applying Calsmooth Lotion may help soothe irritated skin and reduce scratching, which can help prevent further skin irritation.
Yes, Calsmooth Lotion may help soothe skin discomfort associated with mild sunburn, heat exposure, and minor skin irritation. The cooling effect can help reduce the feeling of burning and irritation while the skin recovers.
Calsmooth Lotion may be used on certain areas of the face if advised by your doctor. However, avoid getting the lotion into your eyes, nose, mouth, or other sensitive areas, as this may cause irritation.
No. Calsmooth Lotion is generally intended for use on intact skin. Avoid applying it to open wounds, cuts, severely damaged skin, or areas with active bleeding unless specifically advised by your doctor.
If you are using other medicated creams, ointments, or skin treatments, it is best to discuss this with your doctor. Applying multiple products to the same area at the same time may affect how well they work or increase skin irritation.
Yes, Calsmooth Lotion may be used for short periods as directed when symptoms such as itching or irritation are present. If symptoms continue despite regular use, the underlying cause may need further evaluation.
Some individuals may notice a soothing and cooling effect soon after application. However, the time needed for itching and irritation to improve can vary depending on the cause and severity of the skin condition.
If your itching, rash, or skin irritation continues, worsens, or keeps returning despite regular use of Calsmooth Lotion, you should speak with your doctor. Persistent symptoms may require further evaluation to identify the underlying cause and determine the most appropriate treatment.
Fact Box
Habit Forming
No
Therapeutic Class
DERMA
References
- Fox LP, Merk HF, Bickers DR. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1679-1706.
- Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1047-1065.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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