Delivering to Gurgaon
Hi, there!
Login / Sign Up
Buy medicines
Buy health products
Book lab tests
Consult a doctor
1mg Care Plan
Cancer Care
Ayurveda
Partnerships
New
Hindi articles
Offers
All diseases
New
All medicines
Medicines by therapeutic class
Contact us
Need help?
Privacy policy
Return policy
Terms and conditions
Editorial policy
Get more features! Download the app now
Medicine Reminders
Monthly/weekly subscriptions
Health records and analysis
24*7 Emergency services
Download app on the App StoreDownload app on the Google play store
Choose city
Sign in to your account
or
By signing in you agree to our
Terms & conditions
 and 
Privacy policy
sold out tag

Calsafe-Plus Softgel Capsule

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 25 Nov 2025 | 11:28 PM (IST)
Calsafe-Plus Softgel Capsule is a combination of medicines that is used to treat nutritional deficiencies. It helps in the absorption of calcium and bone strengthening. It helps in proper growth and development of bones. It also helps in protein synthesis and the production of blood cells (red and white blood cells).
Genuine
Authenticity Assured
Prescription
required
₹193 MRP ₹210.949% off 
 
 
0
footer-icon
sku_image
Calsafe-Plus Softgel Capsule is currently sold out
Same composition alternative:
Gemcium Soft Gelatin Capsule
₹141₹192.09
Available alternative from Top Brand
Sold out
Calsafe-Plus Softgel Capsule
Calsafe-Plus Softgel Capsule
strip of 15 soft gelatin capsules
₹193
₹210.94
tag icon
Same composition
Gemcium Soft Gelatin Capsule
Gemcium Soft Gelatin Capsule
strip of 10 soft gelatin capsules
Calcitriol (0.25mcg) + Calcium Carbonate (500mg) + Zinc Sulfate (7.5mg)
by Cadila Pharmaceuticals Ltd
Get by 2pm, Tomorrow
₹141
₹12.0 per unit

₹120

order for
₹1200

Save more with additional offers

offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon
offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon
offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Get cashback up to ₹500
Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.
chevron icon
offer icon
Get upto Rs.150 Cashback
Get upto Rs.150 Cashback
chevron icon

General Information

Contains

Calcitriol (0.25mcg)+ Calcium Carbonate (500mg)+ Zinc Sulfate (7.5mg)

Marketer

Safe Life Care

Storage

Store below 25°C
The content is shown in English
Calsafe-Plus Softgel Capsule image
Calsafe-Plus Softgel Capsule image
Calsafe-Plus Softgel Capsule image

Product introduction

Calsafe-Plus Softgel Capsule may be taken with or without food. It should be used in the dose and duration as prescribed by your doctor. It is advised to take this medicine at a fixed time.

This medicine should not be taken more than the recommended dose. It is usually a safe medicine with very minimal or no side effects. However, if you experience severe diarrhea, vomiting, or constipation, you should consult your doctor without delay.

Before taking this medicine, tell your doctor if you have any other health conditions. Inform your doctor if you are taking any other medicines or if you are pregnant or breastfeeding. It is advised not to take alcohol after taking this medicine.

Uses of Calsafe-Plus Soft Gelatin Capsule

  • Vitamin & mineral deficiency

Benefits of Calsafe-Plus Soft Gelatin Capsule

Vitamin & mineral deficiency
Calsafe-Plus Softgel Capsule is a calcium supplement that helps in the treatment of calcium deficiency. It improves the level of vitamin D in your blood which in turn helps in absorption of more calcium from your intestine. Calsafe-Plus Softgel Capsule will help to keep your bones strong and healthy and reduce the risk of any bone disorders like osteoporosis.

Side effects of Calsafe-Plus Soft Gelatin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Calsafe-Plus
  • Limited data available

How to use Calsafe-Plus Soft Gelatin Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Calsafe-Plus Softgel Capsule may be taken with or without food.

How Calsafe-Plus Soft Gelatin Capsule works

Calsafe-Plus Softgel Capsule is a combination of three medicines: Calcitriol, Calcium Carbonate and Zinc Sulfate which treat osteoporosis. Calcitriol helps your body effectively absorb Calcium Carbonate and additionally supports the muscles needed to avoid falls. Calcium Carbonate and Zinc Sulfate help build and maintain bones.

All substitutes for Calsafe-Plus Softgel Capsule

For information purposes only. Consult a doctor before taking any medicine.

Cetjoint SG Soft Gelatin Capsule

by Leeford Healthcare Ltd
₹5.52/soft gelatin capsule
57% cheaper
<h3 class=bodySemiBold>Cetjoint SG Soft Gelatin Capsule</h3>

Calgel Soft Gelatin Capsule from Intas for Bone and Nerves Health

by Intas Pharmaceuticals Ltd
₹12.67/soft gelatin capsule
2% cheaper
<h3 class=bodySemiBold>Calgel Soft Gelatin Capsule from Intas for Bone and Nerves Health</h3>

Gemsoline Soft Gelatin Capsule from Medley for Bone, Joint and Muscle Care

by Medley Pharmaceuticals
₹14.4/soft gelatin capsule
12% costlier
<h3 class=bodySemiBold>Gemsoline Soft Gelatin Capsule from Medley for Bone, Joint and Muscle Care</h3>

Gemcium Soft Gelatin Capsule

by Cadila Pharmaceuticals Ltd
₹14.1/soft gelatin capsule
10% costlier
<h3 class=bodySemiBold>Gemcium Soft Gelatin Capsule</h3>

GEMcal Soft Gelatin Capsule

by Alkem Laboratories Ltd
₹23.67/soft gelatin capsule
84% costlier
<h3 class=bodySemiBold>GEMcal Soft Gelatin Capsule</h3>

Quick tips

  • Calsafe-Plus Softgel Capsule is used in the treatment of calcium deficiency.
  • Inform your doctor if you have kidney problems, or if you have ever had kidney stones.
  • Let your doctor know if you are taking any other medications like for bone disorders, antihypertensives, antibiotics, antacids, other calcium supplements or medicines for heart disease.
  • Inform your doctor if you are taking an iron supplement, as the absorption rate might be affected.
  • Include calcium-rich food in your diet like milk, cheese, yogurt, calcium-fortified soya milk, and green leafy vegetables like spinach.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Calsafe-Plus Softgel Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Calsafe-Plus Softgel Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Calsafe-Plus Softgel Capsule during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Calsafe-Plus Softgel Capsule does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Calsafe-Plus Softgel Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Calsafe-Plus Softgel Capsule in patients with liver disease.

Frequently asked questions

Calsafe-Plus Softgel Capsule is used to support bone health and prevent conditions like osteoporosis. It helps maintain proper calcium and vitamin D levels in the body, keeping your bones strong and reducing the risk of fractures, especially in older adults or postmenopausal women.
You should not take Calsafe-Plus Softgel Capsule with other vitamin D or calcium supplements unless your doctor advises you to. Combining them can raise calcium levels too high in your blood, leading to serious problems such as kidney stones or heart rhythm issues.
Calsafe-Plus Softgel Capsule should not be used by people who have high calcium levels (hypercalcemia), vitamin D toxicity, or known allergies to any of its ingredients. It should also be avoided by those on digitalis medicines, as high calcium levels can trigger dangerous heart rhythm changes.
Taking too much of Calsafe-Plus Softgel Capsule can lead to excess calcium in the blood, which may cause nausea, fatigue, muscle pain, or more serious effects like kidney damage or tissue calcification. Regular blood tests help your doctor ensure your calcium levels stay safe and balanced.
Yes, prolonged high calcium levels can lead to kidney stones or calcium buildup in the kidneys. Patients with kidney disease should use Calsafe-Plus Softgel Capsule carefully and only under medical supervision.
While you are on Calsafe-Plus Softgel Capsule treatment, if you feel extreme thirst, frequent urination, stomach pain, confusion, or notice muscle weakness, these could be signs of high calcium. Contact your doctor immediately if any of these occur while taking this medicine.
It is advised to avoid taking magnesium-containing antacids or zinc-rich supplements while using Calsafe-Plus Softgel Capsule unless prescribed. These can interact with the ingredients and cause unwanted effects like high magnesium or zinc toxicity.
Serious side effects of Calsafe-Plus Softgel Capsule may include severe vomiting, dehydration, restlessness, irregular heartbeat, or kidney complications. These usually happen if the dose is too high or taken for a long time without monitoring. Seek medical help right away if you experience any of these symptoms.
Some medicines, such as thiazide diuretics (used for high blood pressure) and anticonvulsants, may interact with Calsafe-Plus Softgel Capsule and change calcium levels. Always inform your doctor about all medicines you take before starting this medicine.
Yes, Calsafe-Plus Softgel Capsule can be used long-term under medical supervision. However, elderly people may need lower doses because their kidneys process calcium and vitamin D more slowly. Regular monitoring ensures continued safety and effectiveness.

Fact Box

Habit Forming

No

Therapeutic Class

VITAMINS MINERALS NUTRIENTS

References

  1. Zinc Sulfate. Craigavon: Almac Pharma Services Limited; 2016. [Accessed 05 Apr. 2019] (online) Available from:
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities
<h3 class=titleMediumExtraBold>Want to know more</h3>

Want to know more

We provide you with authentic, trustworthy and relevant information
<h3 class=titleMediumExtraBold>Have issue with the content</h3>

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Safe Life Care
Address: SCO-1 , SS Brother Complex 2nd Floor , Sai Road – Baddi 173205

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?
close sheet