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Buftiz MR Tablet is a combination of two medicines used in the treatment of pain due to muscle spasm. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 02 Feb 2026 | 04:05 PM (IST)
₹50.3 MRP ₹56.2511% off 
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General Information

Contains

Ibuprofen (400mg)+ Tizanidine (2mg)

Marketer

Megavision Pharmaceuticals

Storage

Store below 30°C
The content is shown in English
Buftiz MR Tablet image
Buftiz MR Tablet image

Product introduction

Buftiz MR Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, stomach pain, heartburn, indigestion, dizziness, weakness, and sleepiness. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, and liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should consult their doctors before using this medicine as it may cause harm to the developing baby.

Uses of Buftiz Tablet MR

  • Pain due to muscle spasm

Benefits of Buftiz Tablet MR

Pain due to muscle spasm
Buftiz MR Tablet treats pain due to muscle spasm by relaxing stiff muscles. It also reduces swelling in the muscles. Altogether, it helps in easy movement and reduces discomfort. Once you see some improvement, you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly.

Side effects of Buftiz Tablet MR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Buftiz
  • Nausea
  • Stomach pain
  • Heartburn
  • Indigestion
  • Dizziness
  • Weakness
  • Sleepiness
  • Dryness in mouth

How to use Buftiz Tablet MR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Buftiz MR Tablet should be taken with or after food.

How Buftiz Tablet MR works

Buftiz MR Tablet is a combination of two medicines: Ibuprofen and Tizanidine which relieve pain and relax the muscles. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Tizanidine is a muscle relaxant. It works by acting on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

Quick tips

  • You have been prescribed Buftiz MR Tablet to get relief from pain and stiffness in the muscles.
  • Along with taking Buftiz MR Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.
  • You might experience nausea, ask your doctor to prescribe you an antiemetic (anti-sickness medicine) if it troubles you.
  • Immediately seek medical help if you experience hallucinations, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
  • Inform your doctor if you have a history of seizures, heart disease, or stroke.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Buftiz MR Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Buftiz MR Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Buftiz MR Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Buftiz MR Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Buftiz MR Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Buftiz MR Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Buftiz MR Tablet is not advised in patients with severe liver disease. Liver function tests are recommended before the start of treatment and then on a regular basis as advised.

Frequently asked questions

Buftiz MR Tablet is prescribed to relieve pain associated with muscle spasms. It is often used for conditions like strains, sprains, muscle injuries, and other musculoskeletal issues where both pain and muscle stiffness are a problem.<br>
Buftiz MR Tablet is particularly effective for acute pain conditions where muscle spasms are a major component. This includes issues like acute low back pain, neck pain, and pain resulting from muscle-related injuries.<br>
The exact time Buftiz MR Tablet takes to relieve pain is not known. The onset of action can vary from person to person. However, you may start to notice a decrease in pain and muscle spasticity within 1 hour of taking it, helping to improve your mobility and physical function relatively quickly.<br>
Yes. It is generally recommended to take Buftiz MR Tablet with food. This can help to prevent potential stomach upset, which can be a side effect of the diclofenac component of the medicine.<br>
The tizanidine component of Buftiz MR Tablet can have an effect on blood pressure and heart rate. It is important that you do not stop taking this medicine suddenly without talking to your doctor, as this could cause a rebound effect, including a sudden increase in blood pressure.<br>

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Fu JL, Perloff MD. Pharmacotherapy for Spine-Related Pain in Older Adults. Drugs Aging. 2022 Jul;39(7):523-550. [Accessed 29 Nov. 2025]. Available from:
  2. Berry H, Hutchinson DR. Tizanidine and ibuprofen in acute low-back pain: results of a double-blind multicentre study in general practice. J Int Med Res. 1988;16(2):83-91. [Accessed 29 Nov. 2025]. Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Megavision Pharmaceuticals
Address: 207, R.G. Complex, Plot No. 1, F Block, Prashant Vihar, Rohini, Sector 14, Delhi-110085.

Vendor Details

Country of origin: India

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