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Brupal 300mg/325mg Tablet contains two painkiller medicines. They work together to reduce pain, fever, and inflammation. It is used to treat many conditions such as headache, muscle pain, pain during periods, toothache, and joint pain.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 07 Jun 2026 | 12:54 AM (IST)
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General Information

Contains

Ibuprofen (300mg)+ Paracetamol (325mg)

Marketer

Geno Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Brupal 300mg/325mg Tablet image
Brupal 300mg/325mg Tablet image
Brupal 300mg/325mg Tablet image

Product introduction

Take Brupal 300mg/325mg Tablet with food to reduce the risk of an upset stomach. The dose and how often you need it will be decided by your doctor. Medicines used to treat pain are usually best taken at the first sign of pain. It is meant for short-term use only. Consult your doctor if the symptoms persist or worsen or if the medicine is required for use beyond 3 days. Side effects are rare if this medicine is used correctly, but it may cause heartburn, indigestion, nausea, vomiting, headache, and stomach pain in some people. Consult your doctor if any of these bother you or do not go away. Before taking Brupal 300mg/325mg Tablet, let your doctor know if you are using blood-thinning medicines, or have asthma or any liver or kidney problems. It may affect the dose or suitability of this medicine. Pregnant or breastfeeding women should consult their doctor before taking this medicine. Let your doctor know about all the other medicines you are taking, as they may affect, or be affected by, this medicine. It is best to avoid drinking alcohol while using this medicine.

Uses of Brupal Tablet

  • Pain relief : Brupal 300mg/325mg Tablet helps relieve pain in conditions such as headache, body ache, muscle ache, toothache, menstrual cramps, and minor injuries.
  • Treatment of Fever : Brupal 300mg/325mg Tablet helps relieve fever in conditions such as flu, viral infections, post-vaccination reactions, and other illnesses associated with fever.

Benefits of Brupal Tablet

Pain relief
Pain and inflammation can occur due to injury, strain, or underlying conditions. Brupal 300mg/325mg Tablet works through different mechanisms to reduce pain, swelling, and inflammation. This provides effective relief from conditions such as headache, migraine, back pain, menstrual cramps, dental pain, and muscle aches.
Treatment of Fever
Fever is usually a sign of infection or inflammation in the body. Brupal 300mg/325mg Tablet helps reduce high temperature by blocking chemical messengers that cause fever. This helps bring down the temperature and relieve associated symptoms such as body aches and discomfort. Take it as advised, using the lowest effective dose for the shortest duration.

Side effects of Brupal Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Brupal
  • Heartburn
  • Indigestion
  • Nausea
  • Stomach pain
  • Vomiting
  • Headache
  • Sleepiness

How to use Brupal Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Brupal 300mg/325mg Tablet should be taken with or after food.

How Brupal Tablet works

Brupal 300mg/325mg Tablet is a combination of two medicines: Ibuprofen and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Quick tips

  • Take Brupal 300mg/325mg Tablet with food to reduce stomach irritation.
  • Take Brupal 300mg/325mg Tablet exactly as prescribed by your doctor, and avoid prolonged use without medical supervision.
  • Long-term or excessive use of Brupal 300mg/325mg Tablet may increase the risk of stomach bleeding and kidney problems.
  • Do not take Brupal 300mg/325mg Tablet with other medicines containing paracetamol without consulting your doctor.
  • Avoid taking Brupal 300mg/325mg Tablet with other NSAIDs (such as ibuprofen, diclofenac, or naproxen) unless advised by your doctor.
  • Avoid alcohol while taking Brupal 300mg/325mg Tablet, as it may increase drowsiness and the risk of stomach or liver problems.
  • Watch for warning signs such as severe stomach pain, vomiting blood, or black/tarry stools, and seek medical attention immediately.
  • Stay well hydrated while taking Brupal 300mg/325mg Tablet, especially during fever or hot weather.
  • Inform your doctor if you have a history of asthma triggered by painkillers before taking Brupal 300mg/325mg Tablet.
  • If dizziness occurs after taking Brupal 300mg/325mg Tablet, avoid driving or activities requiring alertness.
  • Consult your doctor if pain or fever persists for more than a few days despite taking Brupal 300mg/325mg Tablet

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Brupal 300mg/325mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Brupal 300mg/325mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

UNSAFE
Brupal 300mg/325mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

UNSAFE
Brupal 300mg/325mg Tablet is unsafe to use in patients with kidney disease and should be avoided.
Liver

Liver

UNSAFE
Brupal 300mg/325mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Brupal 300mg/325mg Tablet may cause side effects such as nausea, vomiting, stomach pain, heartburn, diarrhea, or dizziness in some people. These effects are usually mild and may improve if the medicine is taken with food or milk. Some people may also feel tired or lightheaded. In rare cases, repeated use may affect kidney function or increase blood pressure, particularly in people who are dehydrated or have existing health problems. If side effects persist, worsen, or become severe, consult your doctor.
If you are using Brupal 300mg/325mg Tablet for short-term pain or fever, you can usually stop taking it once your symptoms improve. However, if it has been prescribed for a condition that causes long-term pain, you should continue taking it for the duration recommended by your doctor. Always follow your doctor’s instructions before stopping any medication.
Brupal 300mg/325mg Tablet is a medicine used for short-term relief of pain and fever. It is commonly prescribed for conditions such as headache, body aches, toothache, sore throat pain, muscle pain, joint pain, and inflammation-related discomfort. It works by lowering fever and reducing substances in the body that cause pain and swelling. While it helps relieve symptoms, it does not treat the underlying cause of the illness. If pain or fever continues, consult your doctor.
Brupal 300mg/325mg Tablet should not be taken by people who are allergic to this medicine or to other similar pain relievers known as NSAIDs. It is also not recommended for individuals with stomach ulcers or stomach bleeding, severe liver or kidney disease, uncontrolled high blood pressure, or heart failure unless advised by a doctor. Long-term or improper use may harm the stomach, kidneys, or liver. Always inform your doctor about your medical history before taking Brupal 300mg/325mg Tablet.
Brupal 300mg/325mg Tablet should not be used to treat stomach pain without consulting a doctor. This medicine may increase the risk of stomach irritation and could worsen an underlying stomach condition, such as gastritis or ulcers. If you have persistent stomach pain, it is important to seek medical evaluation rather than self-medicating.
No, taking more than the recommended dose of Brupal 300mg/325mg Tablet is not safe and will not necessarily provide better pain relief. Higher doses can increase the risk of side effects such as nausea, vomiting, stomach irritation, heartburn, and diarrhoea. Repeated or excessive use may also cause kidney damage or liver damage. If the prescribed dose does not control your pain or fever, consult your doctor instead of increasing the dose on your own.
Brupal 300mg/325mg Tablet is generally not recommended during pregnancy unless your doctor specifically advises it. One of its components, ibuprofen, may affect the baby’s circulation and kidney function, especially during the later stages of pregnancy. Because of these risks, pregnant women should avoid self-medicating with this medicine. If you experience pain or fever during pregnancy, consult your doctor so a safer treatment option can be recommended.
Brupal 300mg/325mg Tablet should only be given to children if advised by a doctor. Children require doses based on their age and weight, and certain medicine combinations may not be suitable for all ages. Although it can reduce fever and pain, improper use may increase the risk of overdose, especially if other medicines contain similar ingredients. Consult a doctor before giving Brupal 300mg/325mg Tablet to a child.
Yes, ibuprofen can help reduce fever by lowering substances in the body called prostaglandins that are involved in inflammation and temperature regulation. However, fever may return until the underlying cause is treated. If fever lasts more than a few days or the person appears very unwell, medical advice should be sought.
It is best to avoid alcohol while taking Brupal 300mg/325mg Tablet. Alcohol can increase the risk of stomach irritation and bleeding when combined with ibuprofen, and it may also increase the risk of liver damage when combined with paracetamol. If you regularly consume alcohol, discuss this with your doctor before taking Brupal 300mg/325mg Tablet.
While taking Brupal 300mg/325mg Tablet, avoid alcohol and avoid taking the medicine on an empty stomach. If spicy or heavy foods worsen acidity or heartburn, it may help to eat lighter meals during treatment. If you develop stomach pain, black stools, or vomiting that looks like blood, seek medical attention immediately.
Brupal 300mg/325mg Tablet may temporarily reduce pain and inflammation from a tooth infection, but it does not treat the infection itself. Dental infections can spread and may cause swelling, fever, or a bad taste in the mouth. If you suspect a tooth infection, you should consult a dentist or doctor promptly for proper treatment.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Related lab tests

Complete Blood Count

References

  1. ScienceDirect. Paracetamol/Acetaminophen. [Accessed 23 Apr. 2019] (online) Available from:
  2. Acetaminophen and ibuprofen [Prescribing Information]. Greenville, NC: Catalent Greenville Inc.; 2023. [Accessed 14 Aug. 2024] (online) Available from:
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User feedback

Once A Day
50%
Twice A Day
38%
Thrice A Day
12%
Pain relief
67%
Others
33%
Excellent
100%
No Side Effect
100%
With food
100%
Not Expensive
67%
Average
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Geno Pharmaceuticals Ltd
Address: Geno Pharmaceuticals Pvt. Ltd., Pharmaceutical Complex, Tivim Industrial Estate, Karaswada, Mapusa, Goa - 403 526

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Brupal 300mg/325mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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