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Brio B Eye Drop
Brinzolamide (1%)+ Brimonidine (0.2%)
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Brio B Eye Drop is a prescription medicine having a combination of medicines that is used to treat glaucoma. It works by decreasing the pressure of fluid in the eye (aqueous humor), which helps in lowering the increased eye pressure.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 16 Dec 2025 | 03:58 PM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 16 Dec 2025 | 03:58 PM (IST)
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General Information
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Product introduction
Brio B Eye Drop is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better.
The most common side effects include burning sensation, irritation, itching, and redness at the application site. If these side effects persist for a longer duration, inform your doctor. In case of accidental contact with your ears, nose, or mouth, immediately rinse it off with water. It is advised not to drive or operate heavy machinery immediately after using this medicine as it may cause temporary blurring of vision.
Uses of Brio B Eye Drop
Benefits of Brio B Eye Drop
Treatment of Glaucoma
Glaucoma is an eye disease that damages the optic nerve which is essential for proper vision. This damage is often caused by an abnormally high pressure in the eye. Brio B Eye Drop is used to reduce swelling and pressure inside the eye. This helps prevent complications of glaucoma such as blindness and improves the vision. This medicine may be used alone or with other eye drops. Glaucoma cannot be prevented. Frequent monitoring, regular checkups can help detect the disease in its early stages.
Glaucoma is an eye disease that damages the optic nerve which is essential for proper vision. This damage is often caused by an abnormally high pressure in the eye. Brio B Eye Drop is used to reduce swelling and pressure inside the eye. This helps prevent complications of glaucoma such as blindness and improves the vision. This medicine may be used alone or with other eye drops. Glaucoma cannot be prevented. Frequent monitoring, regular checkups can help detect the disease in its early stages.
Side effects of Brio B Eye Drop
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Brio B
- Application site reactions (burning, irritation, itching and redness)
- Blurred vision
How to use Brio B Eye Drop
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.
How Brio B Eye Drop works
Brio B Eye Drop is a combination of two medicines: Brinzolamide and Brimonidine. Brinzolamide is an alpha-2 adrenergic receptor agonist while Brimonidine is a sympathomimetic. They work by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.
Quick tips
- Brio B Eye Drop is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss.
- Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
- If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.
- Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- It may cause short term blurring of vision when first used. Use caution before driving or using machines.
- It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away.
- Make sure to use within 4 weeks of opening the bottle.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Brio B Eye Drop during pregnancy is not available. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Brio B Eye Drop during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Brio B Eye Drop may cause temporary visual disturbances. Do not drive until your vision is clear.

Kidney
No interaction found/established

Liver
No interaction found/established
Frequently asked questions
Brio B Eye Drop is used to lower high pressure inside the eye in people with glaucoma (open‑angle), or ocular hypertension. Lowering eye pressure helps reduce the risk of optic nerve damage and vision loss.
People should not use Brio B Eye Drop if they are allergic to any of its ingredients, have had a serious reaction to sulfonamide medicines, or if the patient is a newborn or infant under two years of age.
Although rare, but serious allergic reactions like Stevens‑Johnson syndrome, severe skin rashes, or blood problems can occur. If you develop a severe rash, swelling, or difficulty breathing, stop the drops immediately and seek emergency help.
Yes, in people with not enough healthy cells on the inner surface of your cornea (low corneal endothelial cell counts), there is a risk of corneal swelling (corneal edema). Your doctor may check your eyes before starting treatment if you are at risk.
No, Brio B Eye Drop has not been studied for acute angle‑closure glaucoma (increased eye pressure due to blockage in drainage pathways of your eye), and should not be relied on as the only treatment for that condition.
Fact Box
Habit Forming
No
Therapeutic Class
OPHTHAL
References
- Brinzolamide + Brimonidine tartrate. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2014 [revised 20 Feb. 2019]. [Accessed 25 Apr. 2019] (online) Available from:
- Brinzolamide [Prescribing Information]. Parsippany, NJ: Teva Pharmaceuticals USA, Inc.; 2021. [Accessed 28th Sept. 2023] (online) Available from:
- Brimonidine tartrate [Prescribing Information]. Bridgewater, NJ: Bausch & Lomb Americas Inc.; 2022. [Accessed 28th Sept. 2023] (online) Available from:
- Brinzolamide and brimonidine tartrate [FDA Label]. Fort Worth, Texas: Alcon Laboratories, Inc.; 2025. [Accessed 29 Oct. 2025] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Sunways India Pvt Ltd
Address: 1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.
Address: 1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Brio B Eye Drop. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Brio B Eye Drop. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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