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Bisthera Tablet helps to treat ulcers in the stomach and intestines. It is also used in combination with other medicines for the treatment of Helicobacter pylori infections.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Mar 2026 | 03:00 PM (IST)
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Bisthera Tablet image
Bisthera Tablet image
Bisthera Tablet image
Bisthera Tablet image

Product introduction

Bisthera Tablet should be used in the dose and duration as advised by your doctor. It should be taken at the same time each day to get the most benefit. Your symptoms may get better after a short time but do not stop taking it until you have finished a full course of treatment, even if you feel well. If you stop taking it early, some bacteria may survive, and the infection may come back. 

The medicine is generally safe to use, however some may experience nausea, diarrhea, indigestion, abdominal pain, and vomiting as a side effect. These side effects bother you or will not go away, your doctor may suggest ways of preventing or reducing them. 

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Uses of Bisthera Tablet

  • Peptic ulcer disease

Benefits of Bisthera Tablet

Peptic ulcer disease
Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Bisthera Tablet reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.

Side effects of Bisthera Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bisthera
  • Diarrhea
  • Nausea
  • Vomiting
  • Indigestion
  • Abdominal pain

How to use Bisthera Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bisthera Tablet may be taken with or without food.

How Bisthera Tablet works

Bisthera Tablet is believed to work by several methods. First, it increases in mucus glycoprotein secretion and may also bind to the gastric mucus layer to act as a diffusion barrier to HCl. It is also known to have cytoprotective effect and enhances mucosal secretion of prostaglandins and bicarbonate.

Quick tips

  • Bisthera Tablet is used for the treatment of stomach ulcers.
  • Before taking Bisthera Tablet, inform your doctor if you have any other gastrointestinal disorders.
  • Bisthera Tablet might cause temporary and harmless darkening of the tongue and/or black stool. Do not panic, just inform your doctor.
  • Have plenty of fluid while taking Bisthera Tablet, particularly with the bedtime dose.
  • Let your doctor know if you are pregnant, planning to become, or breastfeeding.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Bisthera Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Bisthera Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Bisthera Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Bisthera Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Bisthera Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Doctors prescribe colloidal bismuth subcitrate to treat stomach and duodenal ulcers, as part of H. pylori bacterial eradication therapy, and to relieve symptoms of chronic gastritis and indigestion related to ulcers.
Yes, it is commonly included in multi-drug H. pylori eradication regimens, alongside antibiotics like clarithromycin, amoxicillin, and acid suppressants, because it improves cure rates and helps protect the stomach lining.
Yes, when H. pylori is confirmed as the cause of recurrent ulcers, bismuth-based therapy is a proven option to help eradicate the bacteria and reduce the chance of ulcers coming back.
Many people notice less burning and discomfort within a few days as the protective coating forms. Full ulcer healing typically takes several weeks of consistent oral treatment.
Yes, temporary darkening of the tongue and black stools is a harmless and expected effect of oral bismuth. It goes away after you stop the medicine, and it does not mean bleeding.
Avoid foods and drinks that irritate your stomach, like spicy foods, alcohol, caffeine, and smoking. Eating smaller, regular meals supports ulcer healing and medication effectiveness.
Contact your doctor promptly. You may need dose adjustments, additional testing for complications like bleeding, perforation, or a different treatment approach.

Fact Box

Chemical Class

Bismuth derivative

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Enactis Healthcare Pvt Ltd
Address: Malayappan Square', F-3, 1st Floor, 'Gopal Encalve', 37.Mookambiga Nagar 1st Main Road, Noombal, Iyyappanthangal, Chennai-600 056, India

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Country of origin: India
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