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Aztofa 2% Ointment

Tofacitinib (2% w/w)

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Aztofa 2% Ointment is used in the treatment of treat atopic dermatitis (eczema). It works by blocking the release of certain chemical messengers that cause redness, swelling, and itching in the affected area.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 17 Jan 2026 | 06:50 PM (IST)

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General Information

Contains

Tofacitinib (2% w/w)

Marketer

Ranbaxy Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Aztofa 2% Ointment should be used in the dose and duration as prescribed by your doctor. This medicine should be used regularly to get the most benefit from it. Do not use more than you need; it will not clear your condition faster and may cause undesirable side effects.

This medicine is usually safe to use and does not usually cause any side effects. However, if you experience any symptoms while using the medicine, let your doctor know. They may suggest ways to minimize or treat the side effects.

It is not likely that other medicines you take by mouth or injection will affect the way this medicine works, but talk to your doctor before using it if you have recently used another medicine that contains a steroid or had an allergic reaction to another medicine. Pregnant and breastfeeding mothers should consult their doctors before using this medicine.

Uses of Aztofa Ointment

Treatment of Atopic dermatitis

Benefits of Aztofa Ointment

Treatment of Atopic dermatitis
Aztofa 2% Ointment helps manage the symptoms of atopic dermatitis, such as dry, itchy, swollen, and red skin. It reduces dryness and keeps the skin hydrated and moisturized. Apply Aztofa 2% Ointment to the affected area as directed by your doctor to get the most benefit.

Side effects of Aztofa Ointment

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aztofa

Limited data available

How to use Aztofa Ointment

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.

How Aztofa Ointment works

Aztofa 2% Ointment suppresses the overactive immune system by inhibiting certain enzymes called Janus kinases (JAKs). Thus, Aztofa 2% Ointment blocks the production of pro-inflammatory substances (including cytokines) that contribute to the development of inflammation and other symptoms of atopic dermatitis. When used for androgenetic alopecia, Aztofa 2% Ointment prevents the destruction of hair follicles by the overactive immune system. Applying Aztofa 2% Ointment helps in hair regrowth in areas affected by androgenetic alopecia.

All substitutes for Aztofa 2% Ointment

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Apply Aztofa 2% Ointment to the affected areas as a thin film two or three times daily, or as advised by your doctor.
Do not apply to large areas of skin or near sensitive areas such as the private parts or on broken or injured skin.
Remember to wash your hands after applying Aztofa 2% Ointment, unless this is the area being treated.
Avoid direct contact with the eyes, mouth, and nose, and rinse thoroughly in case of accidental contact or seek medical help in case of swallowing.
Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
Use a mild moisturizer regularly to overcome the skin dryness during the course of treatment in case of atopic dermatitis.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Aztofa 2% Ointment is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Aztofa 2% Ointment during breastfeeding is not available. Please consult your doctor.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

What is Aztofa 2% Ointment used for?

Aztofa 2% Ointment is used on the skin to treat mild to moderate atopic dermatitis (AD), also called eczema, by calming the body’s immune signals that cause red, itchy, inflamed skin.

Who should not use Aztofa 2% Ointment?

Individuals should not use Aztofa 2% Ointment if they are allergic to tofacitinib or any ingredient, have active tuberculosis (TB), or any serious infection (like sepsis, or deep fungal/viral infections), have severe liver problems, or are pregnant or breastfeeding.

Can viruses reactivate while using Aztofa 2% Ointment?

Yes, shingles (herpes zoster) can flare while using Aztofa 2% Ointment. Your doctor may pause treatment until it clears. Tell your doctor if you have had shingles or recurrent cold sores.

Are there blood count checks needed while using Aztofa 2% Ointment?

Very low white cells (lymphopenia, neutropenia) or low hemoglobin (anemia) increase infection risk. Although the likelihood is low, doctors may check blood counts at the start, and every three months during Aztofa 2% Ointment use, and may pause, or stop treatment if counts drop below safe levels.

Can Aztofa 2% Ointment increase cancer risk?

Aztofa 2% Ointment contains tofacitinib, which is a JAK inhibitor. Cancers (including lymphoma and certain skin cancers) have been seen with oral JAK inhibitors, but there is no clear evidence with the topical route of Aztofa 2% Ointment. Your doctor will weigh benefits and risks, especially if you smoke now, or in the past, or have had cancer before; report any new or changing skin lesions.

Fact Box

Chemical Class

N- acylpiperidines

Habit Forming

Therapeutic Class

DERMA

Action Class

Janus kinase inhibitors

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1373-74.
CDSCO. Recommendations of the SEC (Dermatology & Allergy) made in its 78th meeting held on 15.02.2023 at CDSCO (HQ), New Delhi. [Accessed 08 Apr. 2023] (online) Available from:
Ferreira RB, Ferreira SB, Neves Neto AC, et al. Topical Tofacitinib as Effective Therapy in Patients with Plaque Psoriasis Responsive to Systemic Drugs but with Resistant Nail Psoriasis. [Accessed 07 Aug. 2023]. (online) Available from:
Tofacitinib [Prescribing Information]. Hyderabad, Telangana: MSN Laboratories Private Limited; 2023.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ranbaxy Laboratories Ltd
Address: SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Aztofa 2% Ointment. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Aztofa 2% Ointment

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Aztofa Ointment

Benefits of Aztofa Ointment

Side effects of Aztofa Ointment

How to use Aztofa Ointment

How Aztofa Ointment works

All substitutes for Aztofa 2% Ointment

Tofatop Ointment

Tofatas Ointment

Tobraza Ointment

Tofatas Ointment

Novanib-T Ointment

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Aztofa 2% Ointment used for?

Who should not use Aztofa 2% Ointment?

Can viruses reactivate while using Aztofa 2% Ointment?

Are there blood count checks needed while using Aztofa 2% Ointment?

Can Aztofa 2% Ointment increase cancer risk?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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