Azokem Plus Tablet is a combination used to treat hypertension (high blood pressure). This medicine helps control blood pressure and prevent future complications such as heart attack and stroke. This medicine is also effective in preserving kidney function in patients with diabetes.
Azokem Plus Tablet may be prescribed alone or in combination with other medicines. It may be taken with or without food. Take it regularly and at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse.
Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor.
Use of this medicine may cause few common side effects such as dizziness, nausea, headache, swelling in the feet or ankles, and sleepiness. Let your doctor know if these side effects bother you or do not go away.
Before taking this medicine, let your doctor know if you have any kidney or liver problems. To make sure it is safe, pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure, and potassium levels in your blood at regular intervals while you are taking this medicine.
In Treatment of Hypertension (high blood pressure)
Azokem Plus Tablet relaxes the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.
Side effects of Azokem Plus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Azokem Plus
Dizziness
Nausea
Headache
Peripheral edema
Sleepiness
How to use Azokem Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Azokem Plus Tablet may be taken with or without food.
How Azokem Plus Tablet works
Azokem Plus Tablet is a combination of two medicines : Olmesartan Medoxomil and Azelnidipine. Olmesartan Medoxomil is an angiotensin receptor blocker (ARB). It relaxes blood vessels by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure, allowing the blood to flow more smoothly to different organs and the heart to pump more efficiently. Azelnidipine is a calcium channel blocker. It regulates the blood pressure by relaxing the blood vessels and reducing the pressure on them, thereby making it easier for the heart to pump more blood throughout the body. In this way, it normalizes the blood pressure in patients with high blood pressure and also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Azokem Plus Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Azokem Plus Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Azokem Plus Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Azokem Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CAUTION
Azokem Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Azokem Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Azokem Plus Tablet?
If you miss a dose of Azokem Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.
Need to proper investigate and examine. So plz consult doctor nearby.or you can consult me at snergy multiple speciality clinic RD CITY ,BALJEET COMPLEX NEAR SRS MARKET SECTOR 52 gurgaon 9XXXXXX .Advice to maintain calories intake as per weight ,regular walk or aerobic exercises ,on time take your medicines and once a month visit your diabetologist for routine examination and investigations. Will definitely controlled your sugar and u can live healthy life.
I'm type 2 diabetic patient with hypertension, l am taking following medicines Tezloc 40 - OD Glimisave Max-1 forte. BBF Glimisave Max-2 forte Cd Rozavel -5. Hs My usual blood pressure -80/145 Usual Blood glucose levels :fasting -120 PP-180 Hba1c - 7.6 Pl suggest me whether I need any change in medicines etc. I'm taking Januvia-100 also
Dr. Nabajit Talukdar
Cardiology
seems ok basically need control of blood pressure and hypertension get an ecg n echo done
Azokem Plus Tablet is a combination of two medicines that is used to lower high blood pressure and reduce long‑term risks such as stroke, heart attack, and kidney damage, especially when one medicine alone is not enough.
How soon might I see results in my blood pressure reading?
The exact time Azokem Plus Tablet takes to control high blood pressure is not known. However, some people see improved blood pressure readings within 1 to 2 weeks, with full effects developing over several weeks of regular daily use and follow‑up checks.
Does Azokem Plus Tablet help with morning blood pressure surges?
Some studies show better control across the day, particularly in the early morning, a high‑risk time for heart and stroke events. Talk to your doctor if you notice high blood pressure readings, especially in the morning.
I had ankle swelling or a fast heartbeat on other calcium channel blocker medicines. Will this be caused by Azokem Plus Tablet?
Azelnidipine present in Azokem Plus Tablet is often better tolerated for swelling and heart‑rate rise compared with some older options. Many patients report improved comfort while maintaining strong blood pressure control. Talk to your doctor if you notice any signs of swelling or a fast heartbeat.
Does Azokem Plus Tablet protect arteries beyond just lowering the numbers?
Yes. Some studies show that Azokem Plus Tablet may help keep blood vessels flexible and reduce inflammation, which can support long‑term arterial health.
Can I take Azokem Plus Tablet with other heart or diabetes medicines?
Azokem Plus Tablet can be taken with other heart or diabetes medicines if prescribed by your doctor. Always share full details of the medicines you are taking. Your doctor will watch for interactions (for example, with water pills, NSAIDs, or potassium‑raising agents) and adjust your treatment plan safely.
If my readings improve, do I keep taking Azokem Plus Tablet?
Yes. High blood pressure (hypertension) is a long‑term condition. Continue taking Azokem Plus Tablet as prescribed and attend regular checkups so your doctor can adjust your treatment for ongoing protection.
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References
Saito I, Kushiro T, Zenimura N, et al. Olmesartan medoxomil and azelnidipine therapy in patients with hypertension and chronic kidney disease in Japan. J Nephrol. 2012 Sep-Oct;25(5):699-708. [Accessed 02 Jan. 2026]. Available from: