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Composition for ASTHESIA

Prilocaine(2.5% w/w),Lidocaine(2.5% w/w)

food interaction for ASTHESIA

alcohol interaction for ASTHESIA

pregnancy interaction for ASTHESIA

lactation interaction for ASTHESIA

Avoid Asthesia cream with grapefruit juice.
Interaction with alcohol is unknown. Please consult your doctor.
Asthesia cream is probably safe to use during pregnancy.
Either animal studies have shown no adverse effect on the fetus, but there is no human studies or animal studies have shown an adverse effect that was not confirmed in human studies. Please consult your doctor.
Asthesia cream is probably safe to use during breastfeeding. Please consult your doctor.


Prilocaine(2.5% w/w)


Prilocaine is used as a local anesthetic during superficial minor surgery and medical procedures.

How it works

Prilocaine belongs to a class of drugs called local anaesthetic. It stops the pain that occurs during surgery or medical procedures.

Common side effects

Numbness, Bradycardia, Cold, Decreased blood pressure, Increased blood pressure, Nausea, Sensation of warmth, Tingling sensation, Vomiting, Dizziness
Lidocaine(2.5% w/w)


It is used to numb an area of body for temporary relief of pain caused by recurrent mouth ulcers, denture irritation, anal or rectal problems. It is also used before minor surgeries as local anesthetic.

How it works

Lidocaine belongs to a class of medications called local anesthetics. It works by stopping the sensation of pain by acting on peripheral nerves in the body.

Common side effects

Hormone imbalance, Allergic reaction, Slow growth in children and teenagers, Rash, Itching, Urticaria


1 Substitutes
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    (5 GM cream in tube)
    Cadila Pharmaceuticals Ltd
    Rs. 27.58/GM of cream
    Rs. 137.90
    save 8% more per GM of cream

Expert advice for ASTHESIA

  • Caution is to be exercised if you have any of the following conditions: glucose-6-phosphate deficiency, congenital or idiopathic methemoglobinemia (blood disorder in which an abnormal amount of methemoglobin, a form of hemoglobin is produced).
  • Prilocaine cream is for topical use only. Do not apply near the eyes or on open wounds.
  • Take precaution while using prilocaine as there is a possibility of temporary loss of sensation and muscle function.
  • Avoid unintentional trauma or injury to the lips, tongue, cheek mucosa, or soft palate when these structures are anesthetized; postpone ingestion of food until normal function returns.
  • The effect of prilocaine may increase for up to 3 hours under occlusive dressing and may persist for 1 to 2?hour even after removal of the cream.
  • Do not drive or operate machinery as prilocaine may make you feel sleepy.
  • Do not apply cream to larger areas or for longer times than those recommended.

Frequently asked questions for ASTHESIA


Q. Is prilocaine an amide or ester?
Prilocaine is an amide.
Q. What is prilocaine used to treat?
Prilocaine is used as a local anesthetic during superficial minor surgery and medical procedures.
Q. Does prilocaine have epinephrine?
No, Prilocaine does not have epinephrine.
Q. Is prilocaine stronger than lidocaine?
Prilocaine is similar to lidocaine but does not cause vasodilation and has lower CNS toxicity.


Q. Are lidocaine, lignocaine, and xylocaine the same things?
Yes. These are all the other names for an amide type local anesthetic, lidocaine. Lidocaine acts by stopping the sensation of pain by acting on peripheral nerves in the body. It is generally available as topical gel formulation however injections are also available. 
Q. Is lidocaine an opiate/ narcotic/ steroid drug/ omega 3/ nitrates/ cholesterol/ contain codeine/ sulpha?
No. Lidocaine (Lox) is an amide type local anesthetic used to relieve pain topically or by an injection. It is not an opiate narcotic, steroid, omega 3, nitrates, and cholesterol. It does not contain codeine or sulpha.
Q. Is lidocaine and Lox2 safe?
Lidocaine (also available as Lox2) is safe for usage when applied topically as instructed by a doctor. Lidocaine in injectable formulation must not be self-medicated. Always follow the doctor’s advice regarding its use.
Q. Is lidocaine a controlled substance / addictive?
No. Lidocaine is not controlled substance or addictive.
Q. Is lidocaine available over the counter?
No. It is categorized as schedule H drug in India and it is available only by prescription given by your doctor
Q. Is Lox (lidocaine) safe to eat?
No. Lidocaine should never be taken by mouth.
Q. Does lignocaine cause swelling/ drowsiness/ makes you high/ weight gain/ kill sperm?
Lignocaine is not known to cause swelling/ drowsiness/ makes you high/ weight gain/ kill sperm. However, if you experience such side effects consult your doctor.
Q. Can I take Advil/ ibuprofen/paracetamol/ Tylenol/ Vicodin/ Nyquil with lidocaine?
Lignocaine can be taken with above mentioned drugs. Consult your doctor regarding its use.


Content on this page was last updated on 31 August, 2014, by Dr. Varun Gupta (MD Pharmacology)