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M.Pharm, B.Pharm
Reviewed By
MBA, MD Pharmacology
Last updated
03 Apr 2025 | 05:45 PM (IST)

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Arzerra 1000mg Solution for Infusion

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Arzerra 1000mg Solution for Infusion is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS). It works by targeting and depleting B cells, a type of white blood cell involved in the immune system’s attack on the nervous system in MS. It helps slow disease progression and reduce the number of relapses.

Arzerra 1000mg Solution for Infusion is administered subcutaneously (under the skin). Administer the medicine as prescribed and do not skip any doses, as consistency helps maintain its effectiveness. To get the most benefit, follow up with your doctor regularly, stay up to date with vaccinations before starting treatment, and monitor for any signs of infection.


Common side effects of Arzerra 1000mg Solution for Infusion include injection-site reactions such as redness, swelling, or pain, as well as flu-like symptoms like fever, headache, chills, and fatigue, especially after the first doses. These symptoms usually improve with time. Some people may experience upper respiratory infections or urinary tract infections. Staying hydrated and practicing good hygiene can help reduce the risk. If side effects become severe or do not go away, consult your doctor for guidance.


Since Arzerra 1000mg Solution for Infusion lowers certain immune cells, it can increase the risk of infections, including serious ones like hepatitis B reactivation or upper respiratory infections. Before starting treatment, your doctor may check for infections and ensure your vaccinations are up-to-date. Avoid live vaccines while on treatment with Arzerra 1000mg Solution for Infusion, as they may not be safe. If you develop signs of infection, such as a persistent fever, sore throat, or unusual tiredness, seek medical advice promptly. People with a weakened immune system or a history of hepatitis B should discuss risks with their doctor before starting Arzerra 1000mg Solution for Infusion.


Pregnant or breastfeeding women should consult their doctor before using Arzerra 1000mg Solution for Infusion, as it may harm the baby. Both men and women should use effective contraception during treatment to prevent pregnancy. Arzerra 1000mg Solution for Infusion is a strong medication, so always follow your doctor's advice and report any concerns promptly to ensure the best results while minimizing risks.


Uses of Arzerra Solution for Infusion

  • Treatment of Relapsing forms of multiple sclerosis (MS)

Benefits of Arzerra Solution for Infusion

In Treatment of Relapsing forms of multiple sclerosis (MS)

In individuals with relapsing forms of multiple sclerosis (MS), Arzerra 1000mg Solution for Infusion helps prevent relapses and slows the disability progression. It also helps reduce inflammation, decrease the frequency of flare-ups, minimize nerve damage, and improve long-term outcomes. When used as prescribed, Arzerra 1000mg Solution for Infusion helps patients maintain their independence, stay active, and improve their overall quality of life.

Side effects of Arzerra Solution for Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Arzerra

  • Headache
  • Fever
  • Muscle pain
  • Chills
  • Tiredness
  • Injection site reactions (pain, swelling, redness)
  • Upper respiratory tract infection
  • Urinary tract infection

How to use Arzerra Solution for Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Arzerra Solution for Infusion works

Arzerra 1000mg Solution for Infusion is a medicine that targets and removes B cells, a type of immune cell that plays a role in multiple sclerosis (MS). It binds to a protein called CD20 on B cells, marking them for destruction. This helps reduce inflammation, lower the number of relapses, and slow down the damage to the nervous system. The treatment keeps B cells under control while allowing some to recover over time.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Arzerra 1000mg Solution for Infusion. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Arzerra 1000mg Solution for Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Arzerra 1000mg Solution for Infusion during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Arzerra 1000mg Solution for Infusion does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Arzerra 1000mg Solution for Infusion in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Arzerra 1000mg Solution for Infusion in patients with liver disease. Please consult your doctor.

What if you forget to take Arzerra Solution for Infusion?

If you missed a dose of Arzerra 1000mg Solution for Infusion, administer it as soon as possible without waiting until the next scheduled dose. Subsequent doses should be administered at the recommended intervals.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Administer Arzerra 1000mg Solution for Infusion as prescribed to maintain effectiveness. Set reminders if needed.
  • Report any signs of infection, such as fever, cough, or sore throat, to your doctor.
  • Get necessary vaccines at least 4 weeks before starting treatment, and avoid live vaccines during treatment.
  • Use birth control during treatment and for at least 6 months after stopping.
  • Drink plenty of water and rest to ease flu-like side effects.
  • Follow up regularly with your doctor to monitor progress and manage side effects early.

Fact Box

Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Anti-CD20 Monoclonal Antibodies

Interaction with drugs

Taking Arzerra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not use Ofatumumab with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If Ofatumumab is essential, ensure a gap of at least 12 months after discontinuing Herpes Zos... More
Do not use Ofatumumab with Cholera Vaccine (Inactivated). If Ofatumumab is essential, ensure a gap of at least 12 months after discontinuing Cholera Vaccine (Inactivated). Please c... More
Do not use Ofatumumab with Purified Vi Polysaccharide Typhoid Vaccine. If Ofatumumab is essential, ensure a gap of at least 12 months after discontinuing Purified Vi Polysaccharide... More

Patient concerns

Multiple sclerosis treatment and medicine.
Dr. Vikas Sharma
Neurology
many availabe; show to a neurologist
Multiple sclerosis need lost cost medicine
Dr. Sunil Sekhri
Diabetology
this forum is for patients to get second opinion about their diseases.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1747-48.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1011.
  3. Ofatumumab [Prescribing Information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2024. [Accessed 03 Apr. 2025] (online) Available from: External Link
  4. Ofatumumab [Summary of Product Characteristics]. Dublin 4, Ireland: Novartis Europharm Limited; 2021. [Accessed 03 Apr. 2025] (online) Available from: External Link
  5. Ofatumumab [Professional Information]. Johannesburg, South Africa: Novartis South Africa (Pty) Ltd.; 2023. [Accessed 03 Apr. 2025] (online) Available from: External Link

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030
Country of origin: United kingdom

163380
Inclusive of all taxes
MRP168520  3% OFF
50.0 ml in 1 vial
SOLD OUT

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