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04 Jul 2019 | 12:44 PM (IST)
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Apidra Solostar 300 IU/ml Injection

Prescription Required


Introduction of Apidra Solostar Injection

Apidra Solostar 300 IU/ml Injection is a type of rapid-acting insulin used in the treatment of diabetes mellitus. It helps to control blood sugar level and prevents long-term complications. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines if prescribed by your doctor. It may cause hypoglycemia (low blood sugar level) as a side effect.

Uses of Apidra Solostar Injection

Apidra Solostar Injection side effects

  • Hypoglycemia (low blood sugar level)

How to use Apidra Solostar Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Apidra Solostar Injection works

Apidra Solostar 300 IU/ml Injection is a fast-acting insulin, starts working within 10-20 minutes after injection. It works similar to insulin produced by the body. Insulin facilitates reuptake of glucose in muscle and fat cell and also block the release of glucose from the liver.

Apidra Solostar Injection related warnings

It is unsafe to consume alcohol with Apidra Solostar 300 IU/ml Injection. Taking Insulin Glulisine with alcohol may affect blood glucose levels in patients with diabetes.
Apidra Solostar 300 IU/ml Injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Apidra Solostar 300 IU/ml Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Apidra Solostar 300 IU/ml Injection should be used with caution in patients with kidney disease. Dose adjustment of Apidra Solostar 300 IU/ml Injection may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Apidra Solostar 300 IU/ml Injection should be used with caution in patients with liver disease. Dose adjustment of Apidra Solostar 300 IU/ml Injection may be needed. Please consult your doctor.
Frequent and regular monitoring of blood glucose levels is advised.

What if you miss a dose of Apidra Solostar Injection?

If you have missed a dose of Apidra Solostar 300 IU/ml Injection, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Expert Advice

  • Take it 15 minutes before a meal or within 20 minutes after starting a meal.
  • Hypoglycemia (low blood sugar level) is a common side effect. Monitor your blood sugar level regularly. 
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites.
  • Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator  (2°C–8°C).
  • Do not use if the preparation is no longer clear and colorless or if it contains particles.

Interaction with Drugs

Taking Apidra Solostar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Psycool, Proparise
Brand(s): Zencort-M, Welone, Rigapred
Brand(s): Defmark, Zacdef, Ecodef
Brand(s): Stacort
Brand(s): Densol
Brand(s): Leparox, Prx
Brand(s): Kopram, Ecit, Escnx
Brand(s): Digeplex T
Brand(s): Nudiglue-C

Patient Concerns

Questions Related to Apidra Solostar

is it curable for Type 1 diabetes or we need continue with insulin injection for life time. thanks
Dr. Satish Kumar Jyoti
Diabetes Specialist
At present there is no cure for type 1 diabetes. But in near future you can expect it's cure in form of stem cell transplant.
whether i could continue my insulin injection for type 1 diabetes for a long time
Dr. Sanjay Bhatt
Diabetes Specialist
Try to reduce the dose of insulin and shift to tablets by control sugar level with the supervision of your doctor.
Do you have any questions related to Apidra Solostar 300 IU/ml Injection?


Q. I am taking pioglitazone for diabetes. Can I take Apidra Solostar with it?

You have to be extra careful if you are taking both pioglitazone and glulisine. Pioglitazone can cause fluid retention in your body, especially when used in combination with insulin. You may develop symptoms and signs of heart failure or if you already have heart failure, it may get aggravated. Take the advice of your doctor.

Q. I started using Apidra Solostar recently and was told to not inject into the same spot over and over again. Why?

If you use the same spot repeatedly, your body reacts by creating changes in the fatty tissue just under the skin. It can either cause lipodystrophy or lipohypertrophy. In lipodystrophy, the fat tissue becomes thin and creates a pit under the skin. Whereas, in lipohypertrophy, a little extra fat tissue grows at the frequently used injection spot and creates a lump just under the skin. Either one of these will change the absorption time of insulin resulting in delayed action. Also, many people do not like the way these lumps and pittings look.

Q. What if I accidentally inject Apidra Solostar into a muscle?

You should learn to correctly inject insulin just beneath the skin, by pinching up some skin and fat. Injecting Apidra Solostar into a muscle would make its absorption even more rapid. As a result, the chance of having a serious episode of hypoglycemia or low blood sugar would increase.

Q. I have been taking metoprolol for high blood pressure for a long time. Do I need to be careful about anything if I have started glulisine now?

Yes, you need to be careful because symptoms of low blood sugar (hypoglycemia) like increased heart rate may not be noticed by you. Keep a regular check on your blood sugar and consult your doctor if the problem persists.

Q. Can Apidra Solostar be stopped once started?

It depends on whether you have type I diabetes mellitus (body does not produce insulin) or type II (body does not respond to insulin). With type I, insulin is the only treatment available, and you cannot stop it. With type II diabetes mellitus, you may be able to go off insulin if you can get your blood sugar under control with proper diet and exercise. Always consult the doctor in case you want to stop Apidra Solostar.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1251.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 733.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 721.
  4. Insulin glulisine. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2004 [revised Aug. 2008]. [Accessed 12 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072
We do not facilitate sale of this product at present


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