Apephen Plus 50mg/2mg/5mg Tablet

Chlorpromazine (50mg)+ Trihexyphenidyl (2mg)+ Trifluoperazine (5mg)

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Apephen Plus 50mg/2mg/5mg Tablet is a combination medicine used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 03 Sep 2026 | 01:04 AM (IST)

₹371 MRP ₹431.2514% off

(Inclusive of applicable taxes)

Gurgaon

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Apephen Plus 50mg/2mg/5mg Tablet

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Same composition

Trinicalm Forte Tablet

strip of 15 tablets

Chlorpromazine (50mg) + Trihexyphenidyl (2mg) + Trifluoperazine (5mg)

by Torrent Pharmaceuticals Ltd

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General Information

Contains

Chlorpromazine (50mg)+ Trihexyphenidyl (2mg)+ Trifluoperazine (5mg)

Marketer

Apex Formulations Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Apephen Plus 50mg/2mg/5mg Tablet should be taken with food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, dryness in mouth, sedation, abnormal heart rhythm, urinary retention, blurred vision, and nervousness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Apephen Plus Tablet

Schizophrenia

Benefits of Apephen Plus Tablet

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Apephen Plus 50mg/2mg/5mg Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Apephen Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Apephen Plus

Limited data available

How to use Apephen Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apephen Plus 50mg/2mg/5mg Tablet should be taken with or after food.

How Apephen Plus Tablet works

Apephen Plus 50mg/2mg/5mg Tablet is a combination of three medicines: Chlorpromazine, Trihexyphenidyl and Trifluoperazine. Chlorpromazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic which works on the nervous system and corrects some of the side effects occurring during antipsychotic treatment. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

All substitutes for Apephen Plus 50mg/2mg/5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Apephen Plus 50mg/2mg/5mg Tablet is given for the treatment of schrizophenia.
It is better to take Apephen Plus 50mg/2mg/5mg Tablet at night as this medicine may produce drowsiness or sleepiness.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Inform your doctor if you are taking any antidepressants.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Apephen Plus 50mg/2mg/5mg Tablet may affect the levels of sugar in your blood.
Avoid exposure to sunlight or tanning beds. Apephen Plus 50mg/2mg/5mg Tablet can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Keep your regular doctor's appointments so your progress can be checked.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Apephen Plus 50mg/2mg/5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Apephen Plus 50mg/2mg/5mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Apephen Plus 50mg/2mg/5mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Apephen Plus 50mg/2mg/5mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Apephen Plus 50mg/2mg/5mg Tablet make u feel dizzy, drowsy or can cause blurred vision. This may affect your driving ability.

Kidney

CAUTION

Apephen Plus 50mg/2mg/5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Apephen Plus 50mg/2mg/5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Apephen Plus 50mg/2mg/5mg Tablet is not considered safe in patients with liver disease as per the available data.

Frequently asked questions

What is Apephen Plus 50mg/2mg/5mg Tablet used for?

Apephen Plus 50mg/2mg/5mg Tablet is used primarily to treat schizophrenia and other serious mental health disorders. It helps to stabilize thoughts, reduce hallucinations, delusions, agitation, aggression, and mood-related symptoms.

Who should avoid taking Apephen Plus 50mg/2mg/5mg Tablet?

Individuals should avoid taking Apephen Plus 50mg/2mg/5mg Tablet if they are allergic to any of its ingredients, have conditions like narrow-angle glaucoma (a serious eye problem), severe central nervous system depression, severe liver or kidney disease, blood disorders, or are in a coma. Always inform your doctor about any medical conditions you have.

What important precautions should I know before using Apephen Plus 50mg/2mg/5mg Tablet?

Before using Apephen Plus 50mg/2mg/5mg Tablet, tell your doctor if you have heart disease, seizures, prostate enlargement, urinary problems, or liver/kidney issues. The medicine may cause dizziness or low blood pressure when standing up, so rise slowly to avoid falls. Use caution if you are elderly, especially if you have dementia.

Are there any serious side effects of Apephen Plus 50mg/2mg/5mg Tablet?

Serious side effects of Apephen Plus 50mg/2mg/5mg Tablet include severe allergic reactions (rash, swelling, difficulty breathing), irregular heartbeat, extreme dizziness, seizures, or muscle stiffness or rigidity. If you notice any of these, seek medical help immediately.

Can Apephen Plus 50mg/2mg/5mg Tablet cause movement problems?

Yes, sometimes Apephen Plus 50mg/2mg/5mg Tablet can cause muscle rigidity, tremors, or restlessness—known as extrapyramidal symptoms. Tell your doctor if you experience such symptoms.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Apex Formulations Pvt Ltd
Address: 3rd Floor Surya Rath Building Panchwati First Lane, Ahmedabad 380 006,Gujarat,India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Neuro Cns

Conventional Antipsychotics

Apephen Plus 50mg/2mg/5mg Tablet

Apephen Plus 50mg/2mg/5mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Apephen Plus Tablet

Benefits of Apephen Plus Tablet

Side effects of Apephen Plus Tablet

How to use Apephen Plus Tablet

How Apephen Plus Tablet works

All substitutes for Apephen Plus 50mg/2mg/5mg Tablet

Chlorfluhex 50 mg/2 mg/5 mg Tablet

Trinicalm Forte Tablet

Resttop Forte 50mg/2mg/5mg Tablet

Cloptri Plus Tablet

Egret Plus 50 mg/2 mg/5 mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Apephen Plus 50mg/2mg/5mg Tablet used for?

Who should avoid taking Apephen Plus 50mg/2mg/5mg Tablet?

What important precautions should I know before using Apephen Plus 50mg/2mg/5mg Tablet?

Are there any serious side effects of Apephen Plus 50mg/2mg/5mg Tablet?

Can Apephen Plus 50mg/2mg/5mg Tablet cause movement problems?

Fact Box

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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