AP Cobal 0.25mg/10mg Tablet is a prescription medicine used to treat anxiety. It calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It also blocks the action of certain chemical messengers on the heart and blood vessels. This reduces heart rate and blood pressure.

AP Cobal 0.25mg/10mg Tablet should not be taken with food, especially protein-rich food. However, it is advisable to take it at the same time each day as this helps to maintain consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has high habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may cause withdrawal symptoms. Avoid consuming alcohol while taking this medicine as this may reduce its effectiveness.

Some common side effects of this medicine include memory impairment, slow heart rate, fatigue, depression, sleep disturbances, nightmares, cold extremities and confusion. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may cause weight gain or weight loss depending upon person to person. To prevent weight gain, you can eat a healthy balanced diet, avoid snacking with high-calorie food and exercise regularly. On the other hand, weight loss can be managed by increasing food portions and consulting a dietitian. Caution should be taken in impaired liver and kidney disease.

Uses of AP Cobal Tablet

Anxiety disorder

Side effects of AP Cobal Tablet

Common

Confusion
Drowsiness
Memory impairment
Slow heart rate
Tiredness
Uncoordinated body movements
Nightmare
Cold extremities

How to use AP Cobal Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. AP Cobal 0.25mg/10mg Tablet is to be taken empty stomach.

How AP Cobal Tablet works

AP Cobal 0.25mg/10mg Tablet is a combination of two medicines: Alprazolam and Propranolol. Alprazolam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in brain. Propranolol is a beta blocker which blocks the action of certain chemical messengers on the heart and blood vessels. This reduces heart rate, blood pressure, and strain on the heart.

Safety Advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with AP Cobal 0.25mg/10mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

AP Cobal 0.25mg/10mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breastfeeding

CONSULT YOUR DOCTOR

AP Cobal 0.25mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

AP Cobal 0.25mg/10mg Tablet may cause side effects which could affect your ability to drive.
AP Cobal 0.25mg/10mg Tablet may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.

Kidney

SAFE IF PRESCRIBED

AP Cobal 0.25mg/10mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of AP Cobal 0.25mg/10mg Tablet may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

AP Cobal 0.25mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of AP Cobal 0.25mg/10mg Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is advisable for dose adjustment.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.

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Patient Concerns

I have hyperacidity pitta gas due to which i have high blood pressure and anxiety disorder some time whwn there is no gas my bp comes normal doctor has given me telpress ct 40 how can the bp come in control and all report are normalMy bp was 160/100

Dr. Aanchal Maheshwari

Ayurveda

Take avipattikar churan 1 spoon twice with water before meal, kaam dudha ras 1 tab twice, brahmi vati 2 tablet twice with water

sir if i mastribute 2 times per day i got nervou and muscle tightness sleepinessand eyes was paining (litle bit) and i have anxiety disorder using tabs from 20 days

Dr. Pranay Gandhi

Sexologist

1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects

Hello sir, I have been taking tablets for anxiety and depression for last one year. Gradually my doctor decreased dosage. Now iam using stresloc, Opiprol(antidepressant), and Alzolam 0.5. With capi gold vitamin tablet.I have generalised anxiety disorder. Six days ago I dint take that stresloc tablet. It's a combination of alprazolam and propranolol. And it's for morning and night. I decided to skip the morning dosage. First day I dint feel anything. But I couldn't sleep well. Second day I was feeling migraine in head. Anxiety has increased. On that day night I felt there was a fluid running in my head. At that same time , I heard some insect sounds coming from my head. It means insects are produced sound at night time and it's pitch level is high. That sound disturbed me a lot and my concentration was always on that. Before that incident I was watching movie through headphone with full sound in my mobile. I always used to watch movies or videos using headphone with full sound . After that incident I used to take that morning dosage also. Anxiety has controlled but still that ringing sound disturbed at some time . Not all time. My question is that ringing sound produced by any ear problem or that anxiety effects. Plz reply fast ly bcoz it affects my concentration Is that ear problem or anxiety effects??

Dr. Vijay Verma

Ear Nose Throat Specialist

See both ear and anxiety issues can cause ringing better get audiometry test if it is normal than ringing is due to anxiety

Having anxiety disorder and depression for the last 4 yrs undergone course for the same but symptoms persist and now having more negative feelings now taking peroxtine release and cloanezapam tablet daily night Suggest cure in homeopath.

Dr. Saurav Arora

Homeopathy

In your case I advise you to visit a homeopathic doctor and take treatment under supervision. In homeopathy symptoms, history and examination is very important. In majority of cases, after a long case taking and case workout, we try to select a constitutional remedy which is used to treat the disease from its root cause. Taking a constitutional treatment shall also take care the reoccurrence of disease.

What is the best ayurvedic medicine for lethargy,dullness,obsessive compulsive disorder, bipolar mood disorder,general anxiety disorder,gas,bloating,low digestive strength,low body energy,low concentration,too much attachment and paranoid behavior?

Dr. Deepak Kumar Soni

Skin Specialist

https://www.1mgayush.com/otc/jiva-ashwagandha-tablet-otc3299671-1 Tablet after lunch & dinner, Take at least 1-2 months.

I am suffering from anxiety disorder and panic disorder since 2009 I was prescribed with clonazepam 1mg-3times a day and cita s 20mg-while a day From 2 weeks I'm getting suicidal thoughts If I stop any one tablet a day I'm getting sick from next day Please suggest me what I have to do. ??

Dr. Jyoti Kapoor Madan

Psychiatrist

Maximum therapeutic dose of Clonazepam is 2mg/day for not more than 4-6weeks. Medicines are optimised till the response come and anxiolytics are generally tapered of. You are expected to maintain regular follow up with your psychiatrist. Current symptoms are suggestive of mood disorder and you need to see your psychiatrist asap so that proper medicines can be prescribed.

Sleeping disorder I.e. Sleeping maintenance problem , random thoughts .can I take a short term antidepressant along with a tablet for fresh sleep.

Dr. Jyoti Kapoor Madan

Psychiatrist

Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Medicines are prescribed after clinical examination. Please see a psychiatrist for prescription.

Dr mera penis ache se pura khada ho nhi pata i mean ekdum tight nhi ho pata thoda dhila dhila sa rhta h to ap bataiye mko kya krna chahiye

Dr. Shyam Gupta

Sexologist

Hello PATIENT to 1mg. Erectile problems can be happen to people at any age having issue like stress, fatigue, disturb relationship, anxiety, alcohol, smoking and medical problems like High BP, Diabetes, obesity etc. My personal advice is lifestyle changes like exercising, losing weight, stopping smoking,curbing alcohol intake, don't wear tight pants, do pelvic kegal exercise. There are medications but they have side effects so i dont advice first. But i strongly recommend to start healthy life with some antioxidant vitamins and healthy diet. You may take vitamin like DHEA cap, L arginine and herbal ashwagandha capsule. Apply Himcolin gel. Concentrate on Yoga and meditation and also take help from your partner. Use these for couple of months if not improved do few blood tests like thyroid, sugar and testosterone and let me know.

Do you have any questions related to AP Cobal 0.25mg/10mg Tablet ?

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Alprazolam. Sandwich, Kent: Pfizer Limited; 1982 [revised Jan. 2019]. [Accessed 22 Apr. 2019] (online) Available from:
Propranolol. Barnstaple, UK: Actavis; 2018. [Accessed 22 Apr. 2019] (online) Available from:
Alprazolam. Kalamazoo, Michigan: Pharmacia & Upjohn Company. [Accessed 22 Apr. 2019] (online) Available from:
Drugs.com. Propranolol Pregnancy and Breastfeeding Warnings. [Accessed 22 Apr. 2019] (online) Available from:

Manufacturer/Marketer Address

III Floor SIDCO Garment Complex, Guindy, Chennai 600 032, India

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