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Amtas Prp Tablet is used to treat hypertension (high blood pressure). This is a combination of two medicines that controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)
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Amtas Prp Tablet image
Amtas Prp Tablet image
Amtas Prp Tablet image
Amtas Prp Tablet image

Product introduction

You can take Amtas Prp Tablet at any time of day, on empty stomach, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

It may cause side effects like ankle swelling, headache, cough, weakness, shortness of breath, and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.

Uses of Amtas Prp Tablet

Benefits of Amtas Prp Tablet

Hypertension (high blood pressure)
Amtas Prp Tablet relaxes the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Amtas Prp Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amtas Prp
  • Ankle swelling
  • Headache
  • Tiredness
  • Palpitations
  • Increased potassium level in blood
  • Sleepiness
  • Cough
  • Taste change
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Decreased blood pressure
  • Upset stomach
  • Erectile dysfunction
  • Eczema

How to use Amtas Prp Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amtas Prp Tablet is to be taken on an empty stomach.

How Amtas Prp Tablet works

Amtas Prp Tablet is a combination of two medicines: amlodipine and perindopril erbumine. This combination helps lower high blood pressure through complementary actions. Amlodipine, which is a calcium channel blocker, relaxes and widens blood vessels to improve blood flow. Perindopril erbumine, which is an ACE inhibitor, reduces the production of angiotensin II, a substance that narrows blood vessels. Together, they decrease vascular resistance, lower blood pressure, and reduce the workload on the heart.

All substitutes for Amtas Prp Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • You have been prescribed Amtas Prp Tablet for the treatment of high blood pressure.
  • Lowering blood pressure reduces the chance of future heart attack & strokes.
  • It may cause dizziness. Get up slowly when rising from a sitting or lying position.
  • Do not take Amtas Prp Tablet if you are pregnant or planning for pregnancy.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Amtas Prp Tablet.
Pregnancy

Pregnancy

UNSAFE
Amtas Prp Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Amtas Prp Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Amtas Prp Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Amtas Prp Tablet usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in some patients. This may affect your driving ability.
Kidney

Kidney

CAUTION
Amtas Prp Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Caution should be advised in patients with renal impairment.
Liver

Liver

CAUTION
Amtas Prp Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

Frequently asked questions

Amtas Prp Tablet is used to treat high blood pressure (hypertension) when a single blood pressure–lowering medication is not effective. It helps relax blood vessels, improve blood flow, and reduce strain on the heart, lowering the risk of heart attack and stroke.
Individuals should not take Amtas Prp Tablet if they are allergic to amlodipine, perindopril, or any ACE inhibitors, or have ever had swelling of the face or throat (angioedema). It is also not suitable for people with very low blood pressure, severe heart failure after a heart attack, or serious narrowing of the heart valves.
Although rare, Amtas Prp Tablet can cause a serious allergic reaction called angioedema, which may lead to swelling of the face, lips, tongue, or throat. This can block breathing and may be life-threatening. If you notice swelling or difficulty breathing, seek emergency medical help immediately.
Some serious side effects of Amtas Prp Tablet include severe dizziness or fainting from low blood pressure, chest pain, irregular heartbeat, kidney problems, yellowing of the skin or eyes (liver issues), or persistent cough. Any sudden swelling of the face or severe abdominal pain should also be reported to a doctor without delay.
Yes, Amtas Prp Tablet can affect kidney function, especially in people with pre-existing kidney problems, diabetes, or those taking diuretics. Your doctor may order regular blood tests to monitor kidney health and potassium levels while you are on this treatment.
Yes, Amtas Prp Tablet can sometimes lower blood pressure too much, especially in patients who are dehydrated, on a low-salt diet, or taking water pills (diuretics). Symptoms of low blood pressure may include dizziness, fainting, or blurred vision. If you feel very weak or lightheaded, you should lie down and contact your doctor.
Yes, people with liver disease should take Amtas Prp Tablet with caution, as amlodipine present in Amtas Prp Tablet is cleared slowly from the body in such cases. Your doctor may closely monitor liver function and adjust your treatment if needed.
Yes, Amtas Prp Tablet can increase potassium in the blood, especially if you already have kidney problems or take other medicines that raise blood potassium levels. High potassium can cause dangerous heart rhythm changes. Regular blood tests help ensure potassium stays in a safe range.
Yes, a persistent dry cough is a known side effect of perindopril, which is part of Amtas Prp Tablet. If the cough becomes bothersome, your doctor may suggest an alternative treatment.

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User feedback

Once A Day
66%
Twice A Day
34%
Hypertension (high blood pressure)
50%
Others
50%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
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