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Amphogen 50mg/10ml
Prescription Required
Product introduction
Amphogen 50mg/10ml is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It destroys the fungal cells to kill them.
Uses of Amphogen Emulsion
- Severe fungal infections
- Kala-azar
Side effects of Amphogen Emulsion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amphogen
- Nausea
- Vomiting
- Chills
- Headache
- Anemia (low number of red blood cells)
- Decreased potassium level in blood
- Abnormal liver function tests
- Decreased magnesium level in blood
- Diarrhea
- Decreased appetite
- Hypotension (low blood pressure)
- Skin rash
- Nephrocalcinosis
- Increased creatinine level in blood
- Abnormal renal function tests
- Renal tubular acidosis
How to use Amphogen Emulsion
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Amphogen 50mg/10ml may be taken with or without food, but it is better to take it at a fixed time.
How Amphogen Emulsion works
Amphogen 50mg/10ml is an antifungal medication. It kills fungi by destroying the fungal cell membrane.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amphogen 50mg/10ml. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Amphogen 50mg/10ml is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Amphogen 50mg/10ml is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amphogen 50mg/10ml may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Amphogen 50mg/10ml is safe to use in patients with kidney disease. No dose adjustment of Amphogen 50mg/10ml is recommended.
However, inform your doctor if you have any underlying kidney disease.
However, inform your doctor if you have any underlying kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Amphogen 50mg/10ml in patients with liver disease. Please consult your doctor.
What if you forget to take Amphogen Emulsion?
If you miss a dose of Amphogen 50mg/10ml, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Take it as per dose and duration suggested by your doctor.
- Amphogen 50mg/10ml can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
- Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.
- Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Chemical Class
Aminoglycosides {Polyenes}
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fungal cell membrane active agent
Interaction with drugs
Taking Amphogen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec
Serious
Brand(s): Adesera, Adheb, Adfovir
Serious
Brand(s): Mikasun, Vizocin, Gramika
Serious
Brand(s): Densol
Serious
Patient concerns
FAQs
Q. Is Amphogen 50mg/10ml fungistatic or fungicidal?
Amphogen 50mg/10ml is fungicidal in nature, it acts by killing the fungus
Q. Is Amphogen 50mg/10ml light sensitive?
Amphogen 50mg/10ml is not light sensitive
Q. What is Amphogen 50mg/10ml liposomal?
Liposomal Amphogen 50mg/10ml is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphogen 50mg/10ml can substantially improves drug safety especially nephrotoxicity associated with the drug
Q. Is Amphogen 50mg/10ml an antibiotic?
Yes, Amphogen 50mg/10ml is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)
Q. Is Amphogen 50mg/10ml testing dose needed?
Yes, administration of Amphogen 50mg/10ml is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity
Q. How is Amphogen 50mg/10ml administered?
Amphogen 50mg/10ml is either administered as intravenous injection or infusion by a registered medical professional only
Q. How does Amphogen 50mg/10ml cause nephrotoxicity and hyperkalemia?
Amphogen 50mg/10ml can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1424.
- Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1571-75.
- Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 836-38.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 68-69.
- Medsacpe. Amphotericin. [Accessed 29 Mar. 2019] (online) Available from:
- Amphotericin B. San Dimas, California: Gilead Sciences, Inc.; 2000. [Accessed 04 Feb. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004; 80(5):4-6. [Accessed 29 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
Marketer details
Name: Genetek Lifesciences Private Limited
Address: Plot No 10, 1st Floor, Chartered Square, Ashok Chowk Nagpur Nagpur MH 440009 IN
Country of origin: India
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₹2424
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MRP₹2500 3% OFF
10.0 ml in 1 bottle
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