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Amnotript-PR Tablet ER is a combination of two medicines used in the treatment of migraine. It works by increasing the levels of chemical messengers in the brain that help in relieving pain sensation. It also helps in elevating your mood and relaxes the nerves in the brain.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
₹73.6 MRP ₹83.4412% off 
 
 
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Amnotript-PR Tablet ER image
Amnotript-PR Tablet ER image
Amnotript-PR Tablet ER image
Amnotript-PR Tablet ER image

Product introduction

Amnotript-PR Tablet ER should be taken on an empty stomach. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you have missed any dose, take it as soon as you remember. Never skip any doses and finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may worsen your symptoms.

Some common side effects of this medicine include sedation, fatigue, slow heart rate, insomnia (difficulty in sleeping), tiredness, blurred vision, dryness in mouth, difficulty in urination, constipation, nightmares, and cold extremities. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

You should avoid alcohol while taking Amnotript-PR Tablet ER, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses of Amnotript-PR Tablet ER

Benefits of Amnotript-PR Tablet ER

Migraine
Amnotript-PR Tablet ER helps treat migraine by changing the way that your nerves receive pain signals. This helps you relax, feel calm, more energetic and also helps you concentrate better. By managing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Amnotript-PR Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amnotript-PR
  • Sedation
  • Weight gain
  • Fatigue
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Slow heart rate
  • Insomnia (difficulty in sleeping)
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Difficulty in urination
  • Constipation
  • Nightmares
  • Cold extremities

How to use Amnotript-PR Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amnotript-PR Tablet ER is to be taken on an empty stomach.

How Amnotript-PR Tablet ER works

Amnotript-PR Tablet ER is a combination of two medicines. Amitriptyline is a is a tricyclic antidepressant. It also stops the movement of pain signals from nerves to the brain thereby relieving pain. Propranolol is a beta blocker. It also widens the blood vessels in the body for better blood flow. This is how Amnotript-PR Tablet ER treats migraine.

All substitutes for Amnotript-PR Tablet ER

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Amnotript-PR Tablet ER helps to ease the pain you feel during a migraine headache.
  • This medicine can only decrease the number and severity of attacks but may not completely stop them.
  • Do not take any other pain killer without consulting your doctor.
  • Some tips that may help avoid a migraine attack:
    a) Have your meals at the same time every day.
    b) Avoid bright lights and extreme temperatures.
    c) Avoid loud music and noisy places.
    d) Avoid chocolates,  cheese, processed food, alcohol, and smoking.
    f) Get sufficient sleep and avoid stress.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Amnotript-PR Tablet ER
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Amnotript-PR Tablet ER during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Amnotript-PR Tablet ER during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Amnotript-PR Tablet ER alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Amnotript-PR Tablet ER in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Amnotript-PR Tablet ER in patients with liver disease.

Frequently asked questions

Amnotript-PR Tablet ER is mainly used for preventing migraine attacks. It also helps people who have migraines with associated problems, such as anxiety, trouble sleeping, high blood pressure, or nerve pain.
People should not take Amnotript-PR Tablet ER if they are allergic to any of its ingredients, have severe liver disease, urinary retention, a very slow heart rate, heart block, cardiogenic shock (a condition where the heart can’t pump enough blood, causing dangerously low blood pressure and poor organ oxygen supply), or asthma. It should also not be used in people taking MAO inhibitors.
Yes, Amnotript-PR Tablet ER can slow down the heart rate and may worsen certain heart conditions. People with existing heart disease should only take it under strict medical supervision.
Serious side effects of Amnotript-PR Tablet ER may include irregular heartbeat, very low blood pressure, fainting, chest pain, severe dizziness, heart attack, or vision changes due to increased eye pressure. Immediate medical attention is advised if these occur.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Amnour Pharmaceuticals Pvt Ltd
Address: 505, Shivram Heights, Mumbai Pune Highway, Pimpri, Pune-41108 Mobile: +91 84840 79433

Vendor Details

Country of origin: India
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