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Amitrion-G Tablet is a combination medicine used for the treatment of neuropathic pain. It works by increasing the level of chemical messengers in the brain. This helps in regulating the mood and stopping the movement of pain signals from nerves to the brain.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Aug 2026 | 01:07 AM (IST)
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General Information

Contains

Gabapentin (300mg)+ Amitriptyline (10mg)

Marketer

Drugswell Pvt. Ltd.

Storage

Store below 30°C
The content is shown in English
Amitrion-G Tablet image
Amitrion-G Tablet image
Amitrion-G Tablet image
Amitrion-G Tablet image
Amitrion-G Tablet image

Product introduction

Amitrion-G Tablet is taken by mouth with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may increase the seizure frequency and can be life-threatening in some cases. Avoid taking antacids with this medicine as antacids make it harder for your body to absorb this medicine.

Some common side effects of this medicine are constipation, difficulty in urination, weight gain, and dryness in mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet.

Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Amitrion-G Tablet

Benefits of Amitrion-G Tablet

Neuropathic pain
Amitrion-G Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain.
Amitrion-G Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.

Side effects of Amitrion-G Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amitrion-G
  • Limited data available

How to use Amitrion-G Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitrion-G Tablet may be taken with or without food.

How Amitrion-G Tablet works

Amitrion-G Tablet is a combination of two medicines: Gabapentin and Amitriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

All substitutes for Amitrion-G Tablet

For information purposes only. Consult a doctor before taking any medicine.

Gabantip AT Tablet

by Sun Pharmaceutical Industries Ltd
₹25.9/tablet
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<h3 class=bodySemiBold>Gabantip AT Tablet</h3>

Laregab-AT Tablet

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₹25.1/tablet
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<h3 class=bodySemiBold>Laregab-AT Tablet</h3>

Tryptomer G 300mg/10mg Tablet

by Dr Reddy's Laboratories Ltd
₹33.5/tablet
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<h3 class=bodySemiBold>Tryptomer G 300mg/10mg Tablet</h3>

Amigaba 300 mg/10 mg Tablet

by Icon Life Sciences
₹22.1/tablet
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<h3 class=bodySemiBold>Amigaba 300 mg/10 mg Tablet</h3>

Laregab-AT Tablet

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₹25.13/tablet
12% costlier
<h3 class=bodySemiBold>Laregab-AT Tablet</h3>

Quick tips

  • Amitrion-G Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
  • Inform your doctor if you are taking any other pain-relieving medicines.
  • Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
  • Avoid taking antacids 2 hours before or after taking Amitrion-G Tablet as they make it harder for your body to absorb the medicine.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amitrion-G Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Amitrion-G Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Amitrion-G Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Amitrion-G Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Amitrion-G Tablet may impair your alertness which may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Amitrion-G Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Amitrion-G Tablet in patients with liver disease.
Use of Amitrion-G Tablet is not recommended in patients with severe liver disease.
All

Frequently asked questions

Amitrion-G Tablet is a combination of two medicines: Gabapentin and Amitriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). This medicine calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation.
No, you should not stop taking Amitrion-G Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you stop taking Amitrion-G Tablet suddenly, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
The use of Amitrion-G Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will also help prevent weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight.
Yes, Amitrion-G Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
The use of Amitrion-G Tablet can affect the sexual life of both men and women. Different sexual problems can occur due to Amitrion-G Tablet like decreased sexual desire, erectile dysfunction (inability to develop or maintain an erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort during intercourse. If you experience these problems, discuss with your doctor. Do not stop taking Amitrion-G Tablet.
Yes, Amitrion-G Tablet can the change the color of the urine to blue or green color. This change in color is expected while using Amitrion-G Tablet, and it is not harmful. Your urine color becomes normal once you stop taking Amitrion-G Tablet.
Serious side effects with Amitrion-G Tablet are uncommon and rare. Tell your doctor as soon as possible if you notice changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior such as restlessness, nervousness or excitement, signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and may need urgent medical attention.
An initial benefit of Amitrion-G Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see the full benefit. It may even take longer in some patients.
If you forget to take the scheduled dose of Amitrion-G Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect. If you are not sure what to do, ask your doctor about taking Amitrion-G Tablet.
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteady when walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heart beat.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Amitrion-G Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while taking Amitrion-G Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Amitrion-G Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
You may need to see your doctor regularly if you have started to take Amitrion-G Tablet. However, if the recommended dosage does not improve your symptoms or you experience some unwanted side effect that affects your routine activities, consult your doctor.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Amitriptyline. Princeton: Sandoz Inc; 2014. [Accessed 22 Apr. 2019] (online) Available from:
  2. Gabapentin. Menlo Park: Depomed; 1993 [revised date]. [Accessed 22 Apr. 2019] (online) Available from:
  3. Gabapentin+Amitriptyline [Product Information]. Ahmedabad, Gujarat: La Renon Healthcare; 2020. [Accessed 16 Sep. 2024] (online) Available from:
  4. Gabapentin and Amitriptyline. Jaipur, Rajasthan: Heveren Healthcare; [Accessed 16 Sep. 2024] (online). Available from:
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Marketer details

Name: Drugswell Pvt. Ltd.
Address: 47-Anshik Bhaptamau, Buddheshwar, Uttar Pradesh-226017

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Amitrion-G Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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