Amiphos 500mg Injection

Dabur India Ltd

Composition for Amiphos 500mg Injection

iconPrescription Required

Primarily used for

Dryness in the mouth after radio therapy of head and neck cancer
1 Injection in 1 vial

Medicine Overview of Amiphos Injection


Uses of Amiphos Injection

Amiphos 500mg Injection is used to prevent dryness in the mouth after radio therapy of head and neck cancer
It is also used to reduce the harmful effect of chemotherapy on the kidneys during treatment with cisplatin.

Side effects of Amiphos Injection


Nausea, Vomiting, Decreased blood pressure, Hiccup, Sleepiness, Dizziness, Flushing (sense of warmth in the face, ears, neck and trunk), Fever, Chills.


How to use Amiphos Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Amiphos Injection works

Amiphos 500mg injection works by removing free radical, harmful elements produced by cisplatin (a medicine used to treat cancer) or radiation therapy in tissues.

In Depth Information on Amiphos Injection

Expert advice for Amiphos Injection

  • Inform your doctor if you suffer from cardiovascular or cerebrovascular conditions such as ischemic heart disease (chest pain, discomfort or frank heart attack), arrhythmias (irregular heartbeats), heart failure, or have a history of stroke or transient ischemic attacks (mini stroke).
  • You need to be adequately hydrated prior to the amifostine infusion.
  • Frequent monitoring of blood pressure is required during infusion and use of antihypertensive drugs 24 hr prior to start of amifostine infusion should be avoided.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Inform your doctor immediately if you develop any skin reaction or reactions in and around the mouth, any time following amifostine administration. 
  • Amifostine is not recommended for use in elderly.
video imgplay img
Special precautions for Amiphos 500mg Injection
Interaction with alcohol is unknown. Please consult your doctor.
Amiphos 500mg Injection may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Amiphos 500mg Injection is probably safe to use during lacta
tion. Limited human data suggests that the drug does not represent a significant risk to the baby.
It is not known whether Amiphos 500mg Injection alters the a
bility to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Amiphos 500mg Injection is probably safe to use in patients
with kidney disease. Limited data available suggests that dose adjustment of Amiphos 500mg Injection may not be needed in these patients. Please consult your doctor.
There is limited information available on the use of Amiphos
500mg Injection in patients with liver disease. Please consult your doctor.
Related Articles

Patient Concerns

Frequently asked questions for Amiphos 500mg Injection

Frequently asked questions for Amifostine

Yes, it is FDA an approved drug
Amiphos is used to reduce toxicity to kidneys associated with cisplatin therapy in patients with advanced ovarian cancer, and in prevention of dry mouth (xerostomia) during radiotherapy for head and neck cancer
It protects the normal cells against the harmful effects of chemotherapy medications and radiation treatment by producing a chemical ‘thiol' that binds to and detoxifies the harmful compounds produced by cisplatin. Amiphos does not interfere with the action of cisplatin.

Substitutes for Amiphos Injection

Natfost 500mg Injection
Natco Pharma Ltd
save 95%
Ethyol 500mg Injection
Fulford India Ltd
₹479.0/ml of Injection
save 75%
Cytofos 500mg Injection
Sun Pharmaceutical Industries Ltd
save 48%
Amfos 500mg Injection
Vhb Life Sciences Inc
save 41%
Top Medical Oncologists
Dr. Sandeep Batra
MBBS, MD, DNB, Diploma, DNB
Dr. Amit Agarwal
MBBS, MD, DM, Fellowship
Dr. Amish Vora
Dr. Nitesh Rohtagi
cross img