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MD (Pharmacology), MBBS
Last updated:
06 Nov 2020 | 09:32 AM (IST)
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Amiget 500mg Injection

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Amiget 500mg Injection is used to prevent dryness in the mouth after radiotherapy of head and neck cancer. It is also used to reduce the harmful effect of chemotherapy on the kidneys during treatment with cisplatin (medicine used to treat cancer).

Amiget 500mg Injection is given as an injection into vein (IV infusion) under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting and decreased blood pressure are some common side effects of this medicine. Consult with your doctor if it does not go away or bothers you. It is advised to stay hydrated before taking this medicine. You will be check for blood pressure before infusion and every 5 minutes during infusion.

Before taking it, tell your doctor if you have heart disease such as irregular heartbeat and heart failure, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Amiget Injection

In Dryness in the mouth after radiotherapy of head and neck cancer

Amiget 500mg Injection is used to decrease dryness in the mouth caused by radiation treatment after surgery for head and neck cancer. It protects the kidneys from harmful effects of the chemotherapy medicine cisplatin in patients that receive this medication for the treatment of ovarian cancer. It is given as an injection by a doctor or nurse and should not be self-administered.

Side effects of Amiget Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amiget

  • Nausea
  • Vomiting
  • Decreased blood pressure
  • Hiccup
  • Sleepiness
  • Dizziness
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Fever
  • Chills

How to use Amiget Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Amiget Injection works

Amiget 500mg Injection works by removing free radical, harmful elements produced by cisplatin (a medicine used to treat cancer) or radiation therapy in tissues.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amiget 500mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Amiget 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Amiget 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Amiget 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Amiget 500mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amiget 500mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Amiget 500mg Injection in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Amiget 500mg Injection
₹1800.0/Injection
Natfost 500mg Injection
Natco Pharma Ltd
₹93.35/Injection
save 95%
Cytofos 500mg Injection
Sun Pharmaceutical Industries Ltd
₹1000/Injection
save 44%
Amfos 500mg Injection
Vhb Life Sciences Inc
₹1125/Injection
save 38%
₹1910/Injection
6% costlier
Ethyol 500mg Injection
Fulford India Ltd
₹13088/Injection
627% costlier

Quick Tips

  • Amiget 500mg Injection is given as an infusion into the vein ( IV infusion) under the supervision of a doctor only.
  • It is advisable to stay hydrated or drink plenty of fluids before taking medicine.
  • You will be monitored for blood pressure before and after every 5 minutes of infusion.
  • Women who could get pregnant should use a reliable method of contraception to prevent pregnancy while taking this medicine.
  • It may cause a decrease in calcium levels. Your doctor may monitor your calcium levels regularly and prescribe supplements if needed.

Fact Box

Chemical Class
Phosphorylated aminosulfhydryl compound
Habit Forming
No
Therapeutic Class
BLOOD RELATED

Patient Concerns

arrow
What treatment for tounge cancer ?
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Surgery, chemotherapy, Radiotherapy Depends on stage of cancer
Sir mere neck me dard rhta h, me tamaku khaati thi kya Ye cancer k lakshan h
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Pain may be sign for cancer, do you have any swelling on neck or in mouth along with that
arrow
Do you have any questions related to Amiget 500mg Injection ?

FAQs

Q. Is Amiget 500mg Injection FDA approved?

Yes, it is FDA an approved drug

Q. What is Amiget 500mg Injection used for?

Amiget 500mg Injection is used to reduce toxicity to kidneys associated with cisplatin therapy in patients with advanced ovarian cancer, and in prevention of dry mouth (xerostomia) during radiotherapy for head and neck cancer

Q. How does Amiget 500mg Injection work?

It protects the normal cells against the harmful effects of chemotherapy medications and radiation treatment by producing a chemical ‘thiol' that binds to and detoxifies the harmful compounds produced by cisplatin. Amiget 500mg Injection does not interfere with the action of cisplatin.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 50-51.
  2. Amifostine. Nijmegen, Netherlands: USB Pharma B.V.; 1999. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

R-4, Khirki Main Road, Malviya Nagar New Delhi- 110 017, (India)
Country of Origin: India

Expires on or after: April, 2021

A licensed vendor partner from your nearest location will deliver Amiget 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹1530
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5 ml in 1 vial
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