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Amicobal 10mg/1500mcg Tablet is a combination of two medicines used to treat neuropathic pain. It works by protecting the nerve fibers against damage, repairing the damaged nerves. This way it effectively relieves the pain sensation and also elevates the mood.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 12 Feb 2026 | 03:51 PM (IST)
₹141 MRP ₹154.699% off 
Gurgaon
 
 
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General Information

Contains

Amitriptyline (10mg)+ Methylcobalamin (1500mcg)

Marketer

Ergos Life Sciences

Storage

Store below 30°C
The content is shown in English
Amicobal 10mg/1500mcg Tablet image
Amicobal 10mg/1500mcg Tablet image

Product introduction

Amicobal 10mg/1500mcg Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly.

There is limited data on the side effects of Amicobal 10mg/1500mcg Tablet. Let your doctor know if you experience any symptoms that bother you or worsen while taking the medicine. They may be able to suggest ways to treat or manage the side effects.


You should avoid alcohol while taking Amicobal 10mg/1500mcg Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses of Amicobal Tablet

Benefits of Amicobal Tablet

Neuropathic pain
Amicobal 10mg/1500mcg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It interferes with pain signals that travel through the damaged nerves and the brain and gives relief from nerve pain. It also contains nutritional supplements that improve nerve conduction.

Side effects of Amicobal Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amicobal
  • Limited data available

How to use Amicobal Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amicobal 10mg/1500mcg Tablet may be taken with or without food.

How Amicobal Tablet works

Amitriptyline and methylcobalamin. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibres and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

All substitutes for Amicobal 10mg/1500mcg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Amicobal TR 10mg/1500mcg Tablet

by Ergos Life Sciences
₹18.1/tablet
28% costlier
<h3 class=bodySemiBold>Amicobal TR 10mg/1500mcg Tablet</h3>

Amtfree-Plus Tablet

by Jagsam Pharma
₹15/tablet
6% costlier
<h3 class=bodySemiBold>Amtfree-Plus Tablet</h3>

Amitrion-M Tablet

by Drugswell Pvt Ltd
₹15.2/tablet
8% costlier
<h3 class=bodySemiBold>Amitrion-M Tablet</h3>

Quick tips

  • Amicobal 10mg/1500mcg Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
  • It may ease the pain within a few days but it may take 2-3 weeks before you see maximum benefit.
  • Inform your doctor if you are taking any other pain relieving medicines.
  • Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
  • Amicobal 10mg/1500mcg Tablet might cause dry mouth. Frequent sips of water may help ease the discomfort.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Amicobal 10mg/1500mcg Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

UNSAFE
Amicobal 10mg/1500mcg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Amicobal 10mg/1500mcg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Amicobal 10mg/1500mcg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Amicobal 10mg/1500mcg Tablet may impair your alertness which may affect your ability to drive.
Kidney

Kidney

CAUTION
Amicobal 10mg/1500mcg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Amicobal 10mg/1500mcg Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Amicobal 10mg/1500mcg Tablet is not recommended in patients with severe liver disease.

Frequently asked questions

Amicobal 10mg/1500mcg Tablet is mainly prescribed to manage neuropathic pain, which is long-lasting pain caused by nerve damage or nerve-related conditions.
Individuals should not take Amicobal 10mg/1500mcg Tablet if they are allergic to its ingredients, have severe liver problems, urinary retention (trouble passing urine), an enlarged prostate, or are taking medicines called MAO inhibitors.
Medicines like amitriptyline (present in Amicobal 10mg/1500mcg Tablet) may rarely increase the risk of suicidal thoughts or unusual behavior changes, especially during the first few months of treatment, or when the dose is changed. Patients and caregivers should watch for mood changes and report them immediately to a doctor.
No, Amicobal 10mg/1500mcg Tablet should be used very cautiously, as even normal doses may trigger a glaucoma attack in people with narrow-angle glaucoma. Always tell your doctor if you have any eye problems.
Yes, in rare cases, Amicobal 10mg/1500mcg Tablet can cause irregular heartbeats, chest pain, or even a heart attack or stroke, especially in people with existing heart disease. Patients with heart conditions should be closely monitored.
Older adults may be more sensitive to side effects of Amicobal 10mg/1500mcg Tablet like confusion, agitation, dizziness, and low blood pressure. Doctors usually start with a lower dose and adjust slowly. Follow your doctor's advice strictly.
Serious side effects of Amicobal 10mg/1500mcg Tablet may include severe chest pain, irregular heartbeat, fainting, yellowing of eyes or skin (liver problems), seizures, difficulty urinating, rash with swelling, or severe confusion. Seek immediate medical attention if you experience any of these symptoms.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Amitriptyline. Princeton: Sandoz Inc; 2014. [Accessed 22 Apr. 2019] (online) Available from:
  2. Gupta JK, Sana QS. Potential Benefits of Methylcobalamin: A Review. Austin J Pharmacol Ther. 2015;3(3):1076. [Accessed 23 Apr. 2019] (online) Available from:
  3. Amitriptyline And Mecobalamine. Centaur: 2022 [Accessed 23 Apr. 2019] (online). Available from:
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User feedback

Once A Day
98%
Twice A Day
1%
Once A Week
1%
Neuropathic pain
94%
Others
6%
Average
52%
Poor
26%
Excellent
22%
Dryness in mouth
30%
No Side Effect
20%
Orthostatic hypotension (sudden lowering of blood pressure on standing)
20%
Constipation
10%
Weight gain
10%
With food
85%
With or without food
15%
Average
50%
Expensive
27%
Not Expensive
23%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ergos Life Sciences
Address: b-701, western edge 2 cooperative housing society, off western express highway, behind metro cash and carry, borivali east, mumbai, maharashtra 400066

Vendor Details

Country of origin: India

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