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Adpep N Tablet is a combination medicine that helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 19 Jun 2026 | 12:55 PM (IST)
₹53.2 MRP ₹59.4110% off 
As per Ministry of Health and Family Welfare
Gurgaon
 
 
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General Information

Contains

Nimesulide (NA)+ Serratiopeptidase (NA)

Marketer

Admac Pharma Ltd

Storage

Store below 30°C
The content is shown in English
Adpep N Tablet image
Adpep N Tablet image

Product introduction

Adpep N Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, and increased liver enzymes. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.


Note: As per the Ministry of Health and Family Welfare, Adpep N Tablet is banned for children under 12 years of age.

Uses of Adpep N Tablet

Benefits of Adpep N Tablet

Pain relief
Pain from inflammation, injury, or swelling can limit movement and affect daily life. Adpep N Tablet helps relieve pain and reduce swelling. This combination provides effective comfort and supports quicker healing, making everyday activities easier and less painful.

Side effects of Adpep N Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Adpep N
  • Nausea
  • Vomiting
  • Diarrhea
  • Increased liver enzymes

How to use Adpep N Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Adpep N Tablet should be taken with or after food.

How Adpep N Tablet works

Adpep N Tablet is a combination of two medicines: Nimesulide and Serratiopeptidase which relieve pain. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.

Quick tips

  • Adpep N Tablet is used to treat various painful conditions.
  • Take it with food to prevent stomach upset.
  • Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
  • Drink plenty of water while taking this medicine.
  • Do not take it with any other pain medicine without asking your doctor first.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Adpep N Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Adpep N Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Adpep N Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Adpep N Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Adpep N Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Adpep N Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Adpep N Tablet is used to relieve pain, swelling, and inflammation with conditions like muscle injuries, joint pain, dental pain, sprains, back pain, and painful swelling after surgery or trauma. It may also aid in reducing the pain and swelling discomfort of inflammatory conditions. You may notice an improvement in pain and stiffness after taking the medicine; make sure you are not taking it for a long time.
Adpep N Tablet contains nimesulide and serratiopeptidase, which work together to reduce pain and swelling in the body. Nimesulide helps block the production of chemicals (prostaglandins) that cause pain, inflammation, and fever. Serratiopeptidase is an enzyme that helps reduce swelling and supports the breakdown of inflammatory proteins, which promotes the recovery of inflamed tissues. Together, they help relieve pain, decrease swelling, and improve movement and comfort in the affected area.
Generally, it is recommended to take Adpep N Tablet after food. Taking it on an empty stomach might increase the possibility of stomach irritation, acidity, nausea, or discomfort in some people. If you have a sensitive stomach, taking it with meals may help increase tolerance.
Adpep N Tablet is generally used for short-term treatment for relief of pain and swelling. It is not to be used for a longer period of time than recommended, particularly without medical supervision. If pain, swelling, or stiffness continues despite regular use, there may be an underlying cause that needs further evaluation.
Yes, Adpep N Tablet can be used to relieve swelling and pain from injuries such as muscle strain, sprains, or tissue inflammation. This combination is often used when pain is associated with tenderness or visible swelling. However, severe injuries or persistent swelling require medical evaluation.
Do not take other pain relievers such as ibuprofen, aspirin, or similar anti-inflammatory medicines unless your doctor tells you to. Taking more than one painkiller together may increase the risk of stomach irritation, bleeding, kidney problems, or other side effects. Always tell your doctor about all the medicines you are taking.
Adpep N Tablet is generally not recommended for children below 12 years of age because children are more sensitive to certain side effects of this drug and should not be given in any circumstances. Make sure to consult your child's doctor if your child has accidentally taken Adpep N Tablet.
Some people may experience effects on liver function with Adpep N Tablet, particularly if taking high doses over a long period. Stop taking the medicine and consult a doctor if you develop any of the following symptoms: yellowing of the eyes or skin, dark urine, unusual tiredness, persistent nausea, vomiting, or loss of appetite. If you have any pre-existing liver disease, use this medicine with caution.
Adpep N Tablet is not generally recommended for long-term daily use unless your doctor has told you to do so. Long-term use may increase your risk of side effects in your stomach, liver, or kidneys. If you need to take pain medications often, your underlying condition may need to be examined again by your doctor.
Yes, Adpep N Tablet may help relieve body pain, muscle soreness, stiffness, and inflammation associated with injuries or painful conditions affecting muscles and joints.
Some injuries or inflammatory conditions may take time to fully resolve. Mild swelling can persist for several days even after the start of treatment. Recovery may also be helped by rest, staying hydrated, and avoiding stress on the affected area. If swelling increases or does not improve, further evaluation may be necessary.
Avoid too much alcohol and don’t take several pain killers together unless advised. Taking the medicine after food and drinking plenty of fluids may help to reduce discomfort in the stomach. Heavy oily meals or fasting for long periods may make acidity worse in some people when using pain medicines.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. European Medicne Agency. Nimesulide; 2004]. [Accessed 02 Apr. 2019] (online) Available from:
  2. Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 02 Apr. 2019] (online) Available from:
  3. ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
  4. PubChem. Serratiopeptidase. [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.

Vendor Details

Country of origin: India

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