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MD (Microbiology), MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
20 Jun 2019 | 12:47 PM (IST)
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Actilyse 20 mg Infusion

Prescription Required


Introduction of Actilyse Infusion

Actilyse 20 mg Infusion helps to break down the blood clots in blood vessels of heart, lungs, and brain. Hence, it is used to treat conditions such as heart attack, pulmonary embolism, and stroke. It is given under the supervision of a doctor as a drip. It is essential that treatment is started as soon as possible after the onset of symptoms. This medicine may increase the risk of bleeding as a side effect. Therefore, it is advised to be careful while shaving, cutting fingernails or toenails, and using sharp objects.

Uses of Actilyse Infusion

Actilyse Infusion side effects

  • Nausea
  • Vomiting
  • Decreased blood pressure
  • Injection site bleeding

How to use Actilyse Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Actilyse Infusion works

Actilyse 20 mg Infusion is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Actilyse Infusion related warnings

Interaction with alcohol is unknown. Please consult your doctor.
Actilyse 20 mg Infusion may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Actilyse 20 mg Infusion is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Not relevant, as Actilyse 20 mg Infusion is intended for use in hospitalised patients.
Actilyse 20 mg Infusion is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Actilyse 20 mg Infusion may not be needed in these patients. Please consult your doctor.
There is limited information available on the use of Actilyse 20 mg Infusion in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Expert Advice

  • It should be given as soon as possible (within 12 hours) after the onset of a heart attack.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
  • Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.

Patient Concerns

Questions Related to Actilyse

I had heart stroke at 25th May 2016. about after 4 months of heart attack my EF level still very low its less than 30. I feeling problem in my legs and hand. I am unable to walk much. Please guide me solution.
Dr. Nabajit Talukdar
Heart Specialist
Need to see u personally u can meet me at medanta call 9XXXXXX
Heart attack before 2 two years. 1 stunt. Block in valve 45%.!-Stroke hefore 1 yr. Diabetic. Cholesterol level 240. Sugar 300 atter food. No medicine taken now. Erectile problem while the sugar level increasing.
Dr. Manju Singh
I would like to suggest you that please consult with your nearest homeopathy doctor because your case require detail case taking
Do you have any questions related to Actilyse 20 mg Infusion?

User Feedback


Q. Can the use of Actilyse increase the risk of bleeding?

Yes, Actilyse increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding even after stopping the use of Actilyse .

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 866.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 45-47.
  3. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 382.
  4. Alteplase (Catheter Clearance). [Accessed 14 Mar. 2019] (online) Available from:External Link
  5. U.S. National Library of Medicine. Alteplase. [revised 03 Dec. 2018]. [Accessed 14 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
A licensed pharmacy from your nearest location will deliver Actilyse 20mg Infusion. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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