AbhayRIG 300IU Injection

Prescription Required
Storage
Store at room temperature (10-30°C)

Introduction

AbhayRIG 300IU Injection is derived from the blood of horses. It neutralizes the virus at the wound site within a few hours. There are two types of Rabies Immunoglobulin (RIG), human (hRIG) and equine (eRIG). Both have similar clinical effectiveness in eliminating the virus at the wound site.

AbhayRIG 300IU Injection is given as an injection by a doctor or nurse. It is indicated in individuals with category III exposures (in-depth injury). RIG neutralizes the rabies virus at the inoculation site before the immune system responds to the vaccine by the production of rabies virus-neutralizing antibodies. Both active (vaccine) and passive immunization (Immunoglobulin) prevent the rabies virus from infiltrating the central nervous system, but become ineffective once the virus has crossed into the central nervous system. AbhayRIG 300IU Injection is administered only once in a lifetime.

The most common side effects include nausea, acute toxicity, rash, and stomach upset. They do not normally last very long. Sitting or lying down can sometimes help. Consult your doctor if any of the side effects persist or worry you.

Before having the injection, you should tell your doctor if you have ever had an allergic reaction to an immunoglobulin. Some other medicines may react with the equine rabies immunoglobulin so talk to your doctor about other medications you are taking as well. You should consult your doctor first if you are pregnant or breastfeeding.

Uses of AbhayRIG Injection

Benefits of AbhayRIG Injection

In Prevention of Rabies

Rabies is a serious disease caused by the rabies virus that is transmitted through the saliva of infected animals. AbhayRIG 300IU Injection is given along with a rabies vaccine to prevent infection caused by the rabies virus to individuals with suspected rabies exposure. It works by neutralizing the virus at the wound site within a few hours before the immune system responds to the vaccine. It is to be administered only by or under the supervision of your doctor. You should not self administer this medicine.

Side effects of AbhayRIG Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of AbhayRIG

  • Nausea
  • Acute toxicity
  • Rash
  • Upset stomach

How to use AbhayRIG Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How AbhayRIG Injection works

AbhayRIG 300IU Injection is an inactivated vaccine (made from a dead virus). It helps develop immunity by forming antibodies, which are proteins that protect against infection caused by viruses present in the vaccine.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with AbhayRIG 300IU Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of AbhayRIG 300IU Injection during pregnancy is not available. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of AbhayRIG 300IU Injection during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether AbhayRIG 300IU Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
AbhayRIG 300IU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of AbhayRIG 300IU Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
AbhayRIG 300IU Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of AbhayRIG 300IU Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take AbhayRIG Injection?

If you miss a dose of AbhayRIG 300IU Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Fact Box

Chemical Class
Vaccines
Habit Forming
No
Therapeutic Class
VACCINES
Action Class
Killed vaccine

Interaction with Drugs

Taking AbhayRIG with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Healgraft, Graftide-M, Mycocel S
LIFE-THREATENING
Brand(s): Thioprinz, Lazorin, Azarid
SERIOUS
Brand(s): Oncomide, Cyclomet, Cyphos
SERIOUS
Brand(s): Empurine
SERIOUS

Patient Concerns

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Prevention of acene and pimples
Dr. Manju Singh
Homeopathy
Wash acne-prone areas only twice a day. Washing removes excess oil and dead skin cells. But too much washing can irritate the skin. Wash affected areas with a gentle cleanser and use oil-free, water-based skin care products. Use non- oily makeup. Choose oil-free cosmetics that won't clog pores. Remove makeup before going to bed. Going to sleep with cosmetics on your skin can clog your pores. Avoid touching or picking at the problem areas. Doing so can trigger more acne. Always use a clean towel or cloth to wipe your face. Always keep your hands clean and wash them regularly so that you may not touch your skin with dirty hands.
Medicine for prevention of pregnancy?
Dr. Pranay Gandhi
Sexology
i pill 1 tablet within 72 hrs of unprotected sex
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FAQs

Q. Is AbhayRIG 300IU Injection better than human rabies immunoglobulin?

AbhayRIG 300IU Injection is more economical as compared to human rabies immunoglobulin (HRIG) and hence more affordable to patients in developing countries, like India. However, AbhayRIG 300IU Injection may cause anaphylaxis (a severe, potentially life-threatening allergic reaction), serum sickness and other allergic reactions and thus, physicians are hesitant to use it.

Q. How effective is AbhayRIG 300IU Injection?

Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of AbhayRIG 300IU Injection combined with anti-rabies vaccine (ARV) is almost invariably effective in preventing rabies, even after high-risk exposure.

Q. Is AbhayRIG 300IU Injection necessary?

AbhayRIG 300IU Injection is not required for patients who have previously received a complete vaccination series of rabies.

Q. How do you administer AbhayRIG 300IU Injection ?

AbhayRIG 300IU Injection should be administered into the muscle (the intramuscularly). If a large volume (> 2mL for children or > 5 mL for adults) is required, it is advised to divide the doses and for each dose a different site should be used. The immunoglobulin and the anti-rabies vaccine should be administered at two different sites of the body.

Q. Is AbhayRIG 300IU Injection painful?

Whether AbhayRIG 300IU Injection is painful or not depends on your pain tolerance. During your initial treatment, a healthcare professional will put AbhayRIG 300IU Injection in the area where you were bitten which can be painful. Therefore, you may need a relatively greater amount of AbhayRIG 300IU Injection may be required to be placed in and around the wound site to ease out your pain and treat infection.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chawan VS, Tripathi RK, Sankhe L, et al. Safety of equine rabies immunoglobulin in grade III bites. Indian J Community Med. 2007;32(1):73-74. [Accessed 04 Apr. 2019] (online) Available from:External Link
  2. Wilde H, Chutivongse S. Equine rabies immune globulin: a product with an undeserved poor reputation. Am J Trop Med Hyg. 1990;42(2):175-8. [Accessed 04 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Road No. 44, Jubilee Hills, Hyderabad – 500033, Telangana, India.
Country of Origin: India

Expires on or after: July, 2021

A licensed vendor partner from your nearest location will deliver AbhayRIG 300IU Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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5 ml in 1 vial
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